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Q6AJJ9 (SYR_DESPS) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:DP2752
OrganismDesulfotalea psychrophila (strain LSv54 / DSM 12343) [Complete proteome] [HAMAP]
Taxonomic identifier177439 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaDesulfobacteralesDesulfobulbaceaeDesulfotalea

Protein attributes

Sequence length552 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 552552Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242014

Regions

Motif130 – 14011"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q6AJJ9 [UniParc].

Last modified September 13, 2004. Version 1.
Checksum: ABBB9C03AAE7895C

FASTA55261,696
        10         20         30         40         50         60 
MIRSQLKELL DRCFQEGVDN GSWSDRGAGK YTVELPKHEG QGDFSTNIAL VLAGIEKRNP 

        70         80         90        100        110        120 
RELAGIVAEK LGLETAIVAG VEIAGPGFVN ITIQPAVWHG VLAEVFSAGE NFGRSQVGAG 

       130        140        150        160        170        180 
RKVMVEFVSA NPTGPLSIGH GRQAILGDSI ARLLEATNHD VFREYYYNNA GRQMRVLGES 

       190        200        210        220        230        240 
TRARYLELIG AEFSFPEDGY QGEYIIDIAQ SLVDEHGEKL KDEPDVEPFK DQAEKAIFKD 

       250        260        270        280        290        300 
ISGTLERMGI HFDNYYNERS LYENGHIDSV VQELRDKGLV YEKDDAVWFE TTKLGQEKDR 

       310        320        330        340        350        360 
VIIKSTGEPT YRLPDIAYHR EKFKRNFDWL IDIFGSDHIA TVPDVLSGVE ALGYDASKVT 

       370        380        390        400        410        420 
VLLHQFVTLT RDGKQVKMST RKANFVTVDE LIDVVGEDVL RFFYMLRKAD SQLEFDLDLA 

       430        440        450        460        470        480 
TSQSQDNPVY YVQYAHARLC SILAQSGERG IVPAEVGSSL LQRLQEPEEL ALLKTLSGFP 

       490        500        510        520        530        540 
AAIEGSALDL APHKFIHYLM EFAGQFHSYY NKHKVITEDL ELSQARLCLI QALQLTLQNG 

       550 
LHIIGLTAPK SM 

« Hide

References

[1]"The genome of Desulfotalea psychrophila, a sulfate-reducing bacterium from permanently cold Arctic sediments."
Rabus R., Ruepp A., Frickey T., Rattei T., Fartmann B., Stark M., Bauer M., Zibat A., Lombardot T., Becker I., Amann J., Gellner K., Teeling H., Leuschner W.D., Gloeckner F.-O., Lupas A.N., Amann R., Klenk H.-P.
Environ. Microbiol. 6:887-902(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: LSv54 / DSM 12343.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR522870 Genomic DNA. Translation: CAG37481.1.
RefSeqYP_066488.1. NC_006138.1.

3D structure databases

ProteinModelPortalQ6AJJ9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING177439.DP2752.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAG37481; CAG37481; DP2752.
GeneID2946398.
KEGGdps:DP2752.
PATRIC21715630. VBIDesPsy67261_2989.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMAPRVKGAI.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycDPSY177439:GJW5-2835-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSYR_DESPS
AccessionPrimary (citable) accession number: Q6AJJ9
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: September 13, 2004
Last modified: May 14, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries