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Protein

Pyruvate kinase

Gene

DP3116

Organism
Desulfotalea psychrophila (strain LSv54 / DSM 12343)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + pyruvate = ADP + phosphoenolpyruvate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 5 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. Phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (DP2472)
  4. Enolase (eno)
  5. Pyruvate kinase (DP3116)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

GO - Molecular functioni

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processGlycolysisUniRule annotation
LigandMagnesiumUniRule annotation, PyruvateImported

Enzyme and pathway databases

BioCyciDPSY177439:GJW5-3200-MONOMER.
UniPathwayiUPA00109; UER00188.

Names & Taxonomyi

Protein namesi
Recommended name:
Pyruvate kinaseUniRule annotation (EC:2.7.1.40UniRule annotation)
Gene namesi
Ordered Locus Names:DP3116Imported
OrganismiDesulfotalea psychrophila (strain LSv54 / DSM 12343)Imported
Taxonomic identifieri177439 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfobacteralesDesulfobulbaceaeDesulfotalea
Proteomesi
  • UP000000602 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi177439.DP3116.

Structurei

3D structure databases

ProteinModelPortaliQ6AII5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 338PKInterPro annotationAdd BLAST337
Domaini354 – 467PK_CInterPro annotationAdd BLAST114
Domaini500 – 571PEP-utilizersInterPro annotationAdd BLAST72

Sequence similaritiesi

Belongs to the pyruvate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CA9. Bacteria.
COG0469. LUCA.
COG3848. LUCA.
HOGENOMiHOG000021559.
KOiK00873.
OMAiGSYEDHA.
OrthoDBiPOG091H02AT.

Family and domain databases

Gene3Di3.40.1380.20. 1 hit.
InterProiView protein in InterPro
IPR008279. PEP-util_enz_mobile_dom.
IPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
IPR011037. Pyrv_Knase-like_insert_dom.
IPR015793. Pyrv_Knase_brl.
IPR015795. Pyrv_Knase_C.
IPR036918. Pyrv_Knase_C_sf.
PANTHERiPTHR11817. PTHR11817. 1 hit.
PfamiView protein in Pfam
PF00391. PEP-utilizers. 1 hit.
PF00224. PK. 1 hit.
PF02887. PK_C. 1 hit.
PRINTSiPR01050. PYRUVTKNASE.
SUPFAMiSSF50800. SSF50800. 1 hit.
SSF51621. SSF51621. 2 hits.
SSF52935. SSF52935. 1 hit.
TIGRFAMsiTIGR01064. pyruv_kin. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6AII5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKTKIIATL GPQSQSVEEI YSLIQAGMNV ARINLSHGDA ESYKHLISNV
60 70 80 90 100
KEARKLAEKD TAILLDNRGP EIRVSEMEED IHLVDGEELV ITNRAETVSP
110 120 130 140 150
SRITTNYPQL AGDVQVGSRI LLDDGKLALE VLAIEDEEVI TKVIAGGILS
160 170 180 190 200
SRKRVALPDN EVNLPSLSEK DKEDIAFGVE QDVDFIAASF VRQAGDVWAV
210 220 230 240 250
RKIIEDNGGD QEIIAKIENR QGVNNLDEIL QAANGIMVAR GDLGVEVPAE
260 270 280 290 300
EVPIIQKSII KAANRLGKPV ITATQMLESM ITCPTPTRAE ANDVTNAIFD
310 320 330 340 350
GTDAVMLSGE TAIGKYPVQA VAFLVRCATI AENALDYDHI LANGLQNRRP
360 370 380 390 400
TITDSISYAS CATAADLKAT AIITATSSGS TARMVARYRP KAPVIAVSPS
410 420 430 440 450
PSTIRHLQLI RGVTPLLCNF GSSMDEQLDR VIHAATLAEL IHNGDLVIIT
460 470 480 490 500
AGMPLGPTGT TNMLKVHTVA DICVTGQGIG VKHAQGAVRI IQAEDDWQDL
510 520 530 540 550
PEHTIAVVSS TNESMLKHLG KVRGIIAEAP GLTSHAAIVG RELGIPVICN
560 570 580
VTNALMLFEN DQVITIDGTT GHICYGSTQN T
Length:581
Mass (Da):62,176
Last modified:September 13, 2004 - v1
Checksum:i6B599D7D1444EE3F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR522870 Genomic DNA. Translation: CAG37845.1.
RefSeqiWP_011190357.1. NC_006138.1.

Genome annotation databases

EnsemblBacteriaiCAG37845; CAG37845; DP3116.
KEGGidps:DP3116.

Similar proteinsi

Entry informationi

Entry nameiQ6AII5_DESPS
AccessioniPrimary (citable) accession number: Q6AII5
Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2004
Last sequence update: September 13, 2004
Last modified: October 25, 2017
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported