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Protein

GLTSCR1-like protein

Gene

GLTSCR1L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
GLTSCR1-like protein
Alternative name(s):
Glioma tumor suppressor candidate region gene 1 protein-like
Gene namesi
Name:GLTSCR1L
Synonyms:KIAA0240
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

HGNCiHGNC:21111. GLTSCR1L.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134964468.

Polymorphism and mutation databases

BioMutaiGLTSCR1L.
DMDMi114149731.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10791079GLTSCR1-like proteinPRO_0000248602Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei623 – 6231PhosphoserineCombined sources
Modified residuei980 – 9801PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ6AI39.
MaxQBiQ6AI39.
PaxDbiQ6AI39.
PeptideAtlasiQ6AI39.
PRIDEiQ6AI39.

PTM databases

iPTMnetiQ6AI39.
PhosphoSiteiQ6AI39.

Expressioni

Gene expression databases

BgeeiENSG00000112624.
CleanExiHS_KIAA0240.
GenevisibleiQ6AI39. HS.

Organism-specific databases

HPAiHPA029390.
HPA029391.

Interactioni

Protein-protein interaction databases

BioGridi117053. 9 interactions.
IntActiQ6AI39. 14 interactions.
STRINGi9606.ENSP00000313933.

Structurei

3D structure databases

ProteinModelPortaliQ6AI39.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IG5E. Eukaryota.
ENOG410ZQKZ. LUCA.
GeneTreeiENSGT00530000063935.
HOGENOMiHOG000220887.
HOVERGENiHBG079885.
InParanoidiQ6AI39.
OMAiHLEMTCN.
OrthoDBiEOG091G18DF.
PhylomeDBiQ6AI39.
TreeFamiTF335495.

Family and domain databases

InterProiIPR015671. GSCR1_dom.
[Graphical view]
PfamiPF15249. GLTSCR1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6AI39-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDDDDDSCLL DLIGDPQALN YFLHGPSNKS SNDDLTNAGY SAANSNSIFA
60 70 80 90 100
NSSNADPKSS LKGVSNQLGE GPSDGLPLSS SLQFLEDELE SSPLPDLTED
110 120 130 140 150
QPFDILQKSL QEANITEQTL AEEAYLDASI GSSQQFAQAQ LHPSSSASFT
160 170 180 190 200
QASNVSNYSG QTLQPIGVTH VPVGASFASN TVGVQHGFMQ HVGISVPSQH
210 220 230 240 250
LSNSSQISGS GQIQLIGSFG NHPSMMTINN LDGSQIILKG SGQQAPSNVS
260 270 280 290 300
GGLLVHRQTP NGNSLFGNSS SSPVAQPVTV PFNSTNFQTS LPVHNIIIQR
310 320 330 340 350
GLAPNSNKVP INIQPKPIQM GQQNTYNVNN LGIQQHHVQQ GISFASASSP
360 370 380 390 400
QGSVVGPHMS VNIVNQQNTR KPVTSQAVSS TGGSIVIHSP MGQPHAPQSQ
410 420 430 440 450
FLIPTSLSVS SNSVHHVQTI NGQLLQTQPS QLISGQVASE HVMLNRNSSN
460 470 480 490 500
MLRTNQPYTG PMLNNQNTAV HLVSGQTFAA SGSPVIANHA SPQLVGGQMP
510 520 530 540 550
LQQASPTVLH LSPGQSSVSQ GRPGFATMPS VTSMSGPSRF PAVSSASTAH
560 570 580 590 600
PSLGSAVQSG SSGSNFTGDQ LTQPNRTPVP VSVSHRLPVS SSKSTSTFSN
610 620 630 640 650
TPGTGTQQQF FCQAQKKCLN QTSPISAPKT TDGLRQAQIP GLLSTTLPGQ
660 670 680 690 700
DSGSKVISAS LGTAQPQQEK VVGSSPGHPA VQVESHSGGQ KRPAAKQLTK
710 720 730 740 750
GAFILQQLQR DQAHTVTPDK SHFRSLSDAV QRLLSYHVCQ GSMPTEEDLR
760 770 780 790 800
KVDNEFETVA TQLLKRTQAM LNKYRCLLLE DAMRINPSAE MVMIDRMFNQ
810 820 830 840 850
EERASLSRDK RLALVDPEGF QADFCCSFKL DKAAHETQFG RSDQHGSKAS
860 870 880 890 900
SSLQPPAKAQ GRDRAKTGVT EPMNHDQFHL VPNHIVVSAE GNISKKTECL
910 920 930 940 950
GRALKFDKVG LVQYQSTSEE KASRREPLKA SQCSPGPEGH RKTSSRSDHG
960 970 980 990 1000
TESKLSSILA DSHLEMTCNN SFQDKSLRNS PKNEVLHTDI MKGSGEPQPD
1010 1020 1030 1040 1050
LQLTKSLETT FKNILELKKA GRQPQSDPTV SGSVELDFPN FSPMASQENC
1060 1070
LEKFIPDHSE GVVETDSILE AAVNSILEC
Length:1,079
Mass (Da):115,084
Last modified:September 5, 2006 - v2
Checksum:i92357E9993343A76
GO

Sequence cautioni

The sequence BAA13246 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti446 – 4461R → G in CAH10475 (PubMed:17974005).Curated
Sequence conflicti794 – 7941I → V in CAH10475 (PubMed:17974005).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D87077 mRNA. Translation: BAA13246.2. Different initiation.
CR627378 mRNA. Translation: CAH10475.1.
AL035587, AL353716 Genomic DNA. Translation: CAI21488.2.
AL353716, AL035587 Genomic DNA. Translation: CAI14820.2.
CH471081 Genomic DNA. Translation: EAX04102.1.
BC130302 mRNA. Translation: AAI30303.1.
CCDSiCCDS34451.1.
RefSeqiNP_001305748.1. NM_001318819.1.
NP_056164.1. NM_015349.2.
UniGeneiHs.658033.
Hs.713817.

Genome annotation databases

EnsembliENST00000314073; ENSP00000313933; ENSG00000112624.
ENST00000394168; ENSP00000377723; ENSG00000112624.
ENST00000614467; ENSP00000482211; ENSG00000112624.
GeneIDi23506.
KEGGihsa:23506.
UCSCiuc003osn.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D87077 mRNA. Translation: BAA13246.2. Different initiation.
CR627378 mRNA. Translation: CAH10475.1.
AL035587, AL353716 Genomic DNA. Translation: CAI21488.2.
AL353716, AL035587 Genomic DNA. Translation: CAI14820.2.
CH471081 Genomic DNA. Translation: EAX04102.1.
BC130302 mRNA. Translation: AAI30303.1.
CCDSiCCDS34451.1.
RefSeqiNP_001305748.1. NM_001318819.1.
NP_056164.1. NM_015349.2.
UniGeneiHs.658033.
Hs.713817.

3D structure databases

ProteinModelPortaliQ6AI39.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi117053. 9 interactions.
IntActiQ6AI39. 14 interactions.
STRINGi9606.ENSP00000313933.

PTM databases

iPTMnetiQ6AI39.
PhosphoSiteiQ6AI39.

Polymorphism and mutation databases

BioMutaiGLTSCR1L.
DMDMi114149731.

Proteomic databases

EPDiQ6AI39.
MaxQBiQ6AI39.
PaxDbiQ6AI39.
PeptideAtlasiQ6AI39.
PRIDEiQ6AI39.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000314073; ENSP00000313933; ENSG00000112624.
ENST00000394168; ENSP00000377723; ENSG00000112624.
ENST00000614467; ENSP00000482211; ENSG00000112624.
GeneIDi23506.
KEGGihsa:23506.
UCSCiuc003osn.2. human.

Organism-specific databases

CTDi23506.
GeneCardsiGLTSCR1L.
HGNCiHGNC:21111. GLTSCR1L.
HPAiHPA029390.
HPA029391.
neXtProtiNX_Q6AI39.
PharmGKBiPA134964468.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IG5E. Eukaryota.
ENOG410ZQKZ. LUCA.
GeneTreeiENSGT00530000063935.
HOGENOMiHOG000220887.
HOVERGENiHBG079885.
InParanoidiQ6AI39.
OMAiHLEMTCN.
OrthoDBiEOG091G18DF.
PhylomeDBiQ6AI39.
TreeFamiTF335495.

Miscellaneous databases

GenomeRNAii23506.
PROiQ6AI39.

Gene expression databases

BgeeiENSG00000112624.
CleanExiHS_KIAA0240.
GenevisibleiQ6AI39. HS.

Family and domain databases

InterProiIPR015671. GSCR1_dom.
[Graphical view]
PfamiPF15249. GLTSCR1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGSC1L_HUMAN
AccessioniPrimary (citable) accession number: Q6AI39
Secondary accession number(s): A1L3W2, Q5TFZ3, Q92514
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: September 5, 2006
Last modified: September 7, 2016
This is version 94 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.