Q6AH71 (Q6AH71_LEIXX) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Malto-oligosyltrehalose trehalohydrolase PIRNR PIRNR006337
Short name=MTHase PIRNR PIRNR006337
EC=3.2.1.141 PIRNR PIRNR006337

Alternative name(s):
4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehalohydrolase PIRNR PIRNR006337
Maltooligosyl trehalose trehalohydrolase PIRNR PIRNR006337

Gene names

Name:	treZ EMBL AAT88274.1
Ordered Locus Names:	Lxx02200

Organism

Leifsonia xyli subsp. xyli (strain CTCB07) [Complete proteome] [HAMAP]

Taxonomic identifier

281090 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Microbacteriaceae › Leifsonia

Protein attributes

Sequence length	560 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolysis of (1->4)-alpha-D-glucosidic linkage in 4-alpha-D-((1->4)-alpha-D-glucanosyl)(n) trehalose to yield trehalose and (1->4)-alpha-D-glucan. PIRNR PIRNR006337
Pathway	Glycan biosynthesis; trehalose biosynthesis. PIRNR PIRNR006337
Subcellular location	Cytoplasm By similarity PIRSR PIRSR006337-1.
Sequence similarities	Belongs to the glycosyl hydrolase 13 family. PIRNR PIRNR006337

Ontologies

Keywords
Molecular function	Glycosidase PIRNR PIRNR006337 Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	trehalose biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase activity Inferred from electronic annotation. Source: EC cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	245	1	Nucleophile By similarity PIRSR PIRSR006337-1
	Active site	282	1	Proton donor By similarity PIRSR PIRSR006337-1
	Site	377	1	Transition state stabilizer By similarity PIRSR PIRSR006337-3

Sequences

	Sequence		Length	Mass (Da)
	Q6AH71 [UniParc]. Last modified September 13, 2004. Version 1. Checksum: C62807B28DF63E6B	FASTA	560	61,258
	10 20 30 40 50 60 MSDRRFPVWA PRANDVAVVA PALGTFALTA APDGWWRLPE PLDAGPEPLD YGFVVDGGGP 70 80 90 100 110 120 YPDPRSRRQP NGVHALGREF DPDPVEPWPG RELTGAVLYE LHIGTFTPEG TLDAAAGRLG 130 140 150 160 170 180 HLVDLGVEAV ELLPVNAYNG PYGWGYDGVF WYAVHEPYGG PEAYQRFVAA CHRHRIAVIQ 190 200 210 220 230 240 DVVYNHLGPS GNCLPVFGPY LSEGRTAWGS SVNLDGALSD EVRRHILDNA AYWLRDLGAD 250 260 270 280 290 300 GLRLDAVHAF QDSRAEHILE ALARQTAELR EETGRPLTLI AESDLNDPRL IRSRARHGYG 310 320 330 340 350 360 LDAQWNDDAH HSVHANLTGE TSGYYVDFGE PDALVKVFEG GFFHDGTYSA FRERHHGRPL 370 380 390 400 410 420 DADQPHSQLV AFSQNHDQIG NRAAGDRLSA TLDDGRLAVA AALTLLGPFT PMLFMGEEWA 430 440 450 460 470 480 AGTPWPFFAS HPEPDLAEAT RSGRIAEFAR MGWDPTAVAD PMDPATFHAA MLDWSERDSE 490 500 510 520 530 540 RGALMLDWYR ALTRLRRAIP ADARARDVWF ADGAFSFVRD RTRVTASLSG GGLSHSDGTD 550 560 AVLASFGDAV LVTRTPAHPA

References

[1]

"The genome sequence of the Gram-positive sugarcane pathogen Leifsonia xyli subsp. xyli." Monteiro-Vitorello C.B., Camargo L.E.A., Van Sluys M.A., Kitajima J.P., Truffi D., do Amaral A.M., Harakava R., de Oliveira J.C.F., Wood D., de Oliveira M.C., Miyaki C.Y., Takita M.A., da Silva A.C.R., Furlan L.R., Carraro D.M., Camarotte G., Almeida N.F. Jr., Carrer H. , Coutinho L.L., El-Dorry H.A., Ferro M.I.T., Gagliardi P.R., Giglioti E., Goldman M.H.S., Goldman G.H., Kimura E.T., Ferro E.S., Kuramae E.E., Lemos E.G.M., Lemos M.V.F., Mauro S.M.Z., Machado M.A., Marino C.L., Menck C.F., Nunes L.R., Oliveira R.C., Pereira G.G., Siqueira W., de Souza A.A., Tsai S.M., Zanca A.S., Simpson A.J.G., Brumbley S.M., Setubal J.C. Mol. Plant Microbe Interact. 17:827-836(2004) [PubMed: 15305603] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CTCB07.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016822 Genomic DNA. Translation: AAT88274.1.
RefSeq	YP_061379.1. NC_006087.1.
3D structure databases
ProteinModelPortal	Q6AH71.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2939156.
GenomeReviews	Gene locus Lxx02200 in contig AE016822_GR.
KEGG	lxx:Lxx02200.
NMPDR	fig|281090.3.peg.1301.
PATRIC	22333894. VBILeiXyl11655_0218.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG367595.
OMA	EGFVYQG.
Family and domain databases
InterPro	IPR015902. Alpha_amylase. IPR006047. Glyco_hydro_13_cat_dom. IPR013781. Glyco_hydro_subgr_catalytic. IPR017853. Glycoside_hydrolase_SF. IPR013783. Ig-like_fold. IPR014756. Ig_E-set. IPR012768. Trehalose_TreZ. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 2 hits. G3DSA:2.60.40.10. Ig-like_fold. 1 hit.
PANTHER	PTHR10357. Alpha_amylase. 1 hit. PTHR10357:SF21. PTHR10357:SF21. 1 hit.
Pfam	PF00128. Alpha-amylase. 2 hits. [Graphical view]
PIRSF	PIRSF006337. Trehalose_TreZ. 1 hit.
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit. SSF81296. Ig_E-set. 1 hit.
TIGRFAMs	TIGR02402. Trehalose_TreZ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q6AH71_LEIXX

Accession

Primary (citable) accession number: Q6AH71

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2004
Last sequence update:	September 13, 2004
Last modified:	December 14, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)