Q6AGY2 (MQO_LEIXX) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	Lxx03470

Organism

Leifsonia xyli subsp. xyli (strain CTCB07) [Complete proteome] [HAMAP]

Taxonomic identifier

281090 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Microbacteriaceae › Leifsonia

Protein attributes

Sequence length	491 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 491	491	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_0000128720

Sequences

	Sequence		Length	Mass (Da)
	Q6AGY2 [UniParc]. Last modified September 13, 2004. Version 1. Checksum: B1ECEF0824945AFD	FASTA	491	53,621
	10 20 30 40 50 60 MSNDPIDVVL IGGGIMSATL GAMIQRVQPG WSIRIYESLG EVAQESSNPW NNAGTGHAAL 70 80 90 100 110 120 CELNYMPEAE DGTVDPAKAI SINEQFQLSR QFWASLVAAG DLPEPQTFIN STPHMTFVRG 130 140 150 160 170 180 RENVRYLRRR YEELKDQPLF AGMEYSEDAE TIAEWAPLLT KKRNRKQRIA ATRQLAGTDV 190 200 210 220 230 240 DFGALTRALV DDLVASGAEL ALNHRVCSLK RTKDGLWRIR ARHEVGRTPR EALARFVFVG 250 260 270 280 290 300 AGGGALHLLQ KSGISEIEGF GGFPISGQFL RTTNPAIVAQ HKAKVYGKAA VGAPPMSVPH 310 320 330 340 350 360 LDTRVVDGET SLLFGPYAGF SPKFLKTGTW WDLPGSIRLG NIGPMLAVAR DNFDLMKYLI 370 380 390 400 410 420 GELMAGREKK LAALREFMPT AKSEDWELIA AGQRVQVMKK DERKGGVLQF GTEVIAAADG 430 440 450 460 470 480 SIAGLLGASP GASTAVPIMV DLLKRCFPER FEGWLPVLRE LIPTVGTTLN DRPEEAEFVL 490 KRTAAVLKLA Q

References

[1]

"The genome sequence of the Gram-positive sugarcane pathogen Leifsonia xyli subsp. xyli." Monteiro-Vitorello C.B., Camargo L.E.A., Van Sluys M.A., Kitajima J.P., Truffi D., do Amaral A.M., Harakava R., de Oliveira J.C.F., Wood D., de Oliveira M.C., Miyaki C.Y., Takita M.A., da Silva A.C.R., Furlan L.R., Carraro D.M., Camarotte G., Almeida N.F. Jr., Carrer H. , Coutinho L.L., El-Dorry H.A., Ferro M.I.T., Gagliardi P.R., Giglioti E., Goldman M.H.S., Goldman G.H., Kimura E.T., Ferro E.S., Kuramae E.E., Lemos E.G.M., Lemos M.V.F., Mauro S.M.Z., Machado M.A., Marino C.L., Menck C.F., Nunes L.R., Oliveira R.C., Pereira G.G., Siqueira W., de Souza A.A., Tsai S.M., Zanca A.S., Simpson A.J.G., Brumbley S.M., Setubal J.C. Mol. Plant Microbe Interact. 17:827-836(2004) [PubMed: 15305603] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CTCB07.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016822 Genomic DNA. Translation: AAT88363.1.
RefSeq	YP_061468.1. NC_006087.1.
3D structure databases
ProteinModelPortal	Q6AGY2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2939437.
GenomeReviews	Gene locus Lxx03470 in contig AE016822_GR.
KEGG	lxx:Lxx03470.
NMPDR	fig|281090.3.peg.1390.
PATRIC	22334144. VBILeiXyl11655_0339.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG289663.
OMA	NTQFEVS.
ProtClustDB	PRK05257.
Enzyme and pathway databases
BioCyc	LXYL281090:LXX03470-MONOMER.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_LEIXX

Accession

Primary (citable) accession number: Q6AGY2

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 2, 2005
Last sequence update:	September 13, 2004
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program