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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Leifsonia xyli subsp. xyli (strain CTCB07)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Tricarboxylic acid cycle

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

BioCyciLXYL281090:GH0X-321-MONOMER.
UniPathwayiUPA00223; UER01008.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:Lxx03470
OrganismiLeifsonia xyli subsp. xyli (strain CTCB07)
Taxonomic identifieri281090 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesMicrobacteriaceaeLeifsonia
Proteomesi
  • UP000001306 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 491491Probable malate:quinone oxidoreductasePRO_0000128720Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi281090.Lxx03470.

Structurei

3D structure databases

ProteinModelPortaliQ6AGY2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
KOiK00116.
OMAiEPIAATK.
OrthoDBiEOG6X6R8Z.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6AGY2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNDPIDVVL IGGGIMSATL GAMIQRVQPG WSIRIYESLG EVAQESSNPW
60 70 80 90 100
NNAGTGHAAL CELNYMPEAE DGTVDPAKAI SINEQFQLSR QFWASLVAAG
110 120 130 140 150
DLPEPQTFIN STPHMTFVRG RENVRYLRRR YEELKDQPLF AGMEYSEDAE
160 170 180 190 200
TIAEWAPLLT KKRNRKQRIA ATRQLAGTDV DFGALTRALV DDLVASGAEL
210 220 230 240 250
ALNHRVCSLK RTKDGLWRIR ARHEVGRTPR EALARFVFVG AGGGALHLLQ
260 270 280 290 300
KSGISEIEGF GGFPISGQFL RTTNPAIVAQ HKAKVYGKAA VGAPPMSVPH
310 320 330 340 350
LDTRVVDGET SLLFGPYAGF SPKFLKTGTW WDLPGSIRLG NIGPMLAVAR
360 370 380 390 400
DNFDLMKYLI GELMAGREKK LAALREFMPT AKSEDWELIA AGQRVQVMKK
410 420 430 440 450
DERKGGVLQF GTEVIAAADG SIAGLLGASP GASTAVPIMV DLLKRCFPER
460 470 480 490
FEGWLPVLRE LIPTVGTTLN DRPEEAEFVL KRTAAVLKLA Q
Length:491
Mass (Da):53,621
Last modified:September 13, 2004 - v1
Checksum:iB1ECEF0824945AFD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016822 Genomic DNA. Translation: AAT88363.1.

Genome annotation databases

EnsemblBacteriaiAAT88363; AAT88363; Lxx03470.
KEGGilxx:Lxx03470.
PATRICi22334144. VBILeiXyl11655_0339.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016822 Genomic DNA. Translation: AAT88363.1.

3D structure databases

ProteinModelPortaliQ6AGY2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi281090.Lxx03470.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT88363; AAT88363; Lxx03470.
KEGGilxx:Lxx03470.
PATRICi22334144. VBILeiXyl11655_0339.

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
KOiK00116.
OMAiEPIAATK.
OrthoDBiEOG6X6R8Z.

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.
BioCyciLXYL281090:GH0X-321-MONOMER.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CTCB07.

Entry informationi

Entry nameiMQO_LEIXX
AccessioniPrimary (citable) accession number: Q6AGY2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 2, 2005
Last sequence update: September 13, 2004
Last modified: November 11, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.