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Q6AFE9

- Q6AFE9_LEIXX

UniProt

Q6AFE9 - Q6AFE9_LEIXX

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Protein
Alanine racemase
Gene
alr, Lxx10340
Organism
Leifsonia xyli subsp. xyli (strain CTCB07)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei42 – 421Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei138 – 1381Substrate By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotations

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciLXYL281090:GH0X-964-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
Ordered Locus Names:Lxx10340Imported
OrganismiLeifsonia xyli subsp. xyli (strain CTCB07)Imported
Taxonomic identifieri281090 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrobacteriaceaeLeifsonia
ProteomesiUP000001306: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei42 – 421N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi281090.Lxx10340.

Structurei

3D structure databases

ProteinModelPortaliQ6AFE9.

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000031444.
KOiK01775.
OMAiTIADEMV.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 2 hits.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6AFE9-1 [UniParc]FASTAAdd to Basket

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MTIVDAVAEP LPRAVVDLAA LRRNVATLTR LIAPAETMLA VKADAYGHGL    50
LPIAEAGVQA GATSLAVLEI SAGLVLRRAG VTVPLLAWLH GTGTDWRAGI 100
ENDIQLGISA RWQLEAIAAA AADRAAIVHL KVDTGLSRNG ATREEWPALV 150
DAALALQETG VVRLRAAWSH LADASIADDE AALAEFREAV AEAEARGARF 200
EMLHLAASSA GIRMPEARFA LVRFGIAAYG LSPFDDTTGA ELGLRPVMRL 250
EAPVIAVHVD GTTHVRLGIG FADGVPTLGL ARTSVLLGGR RCPVIAVEAD 300
AMLVDAGAQR VERGDTAVLF GPGDSGEATA EEYAEWAGTI ADEMVTGVAA 350
RVPRVYVGDD EGAGLTGTRG 370
Length:370
Mass (Da):38,420
Last modified:September 13, 2004 - v1
Checksum:iF8CE95A4718944CC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016822 Genomic DNA. Translation: AAT88896.1.
RefSeqiYP_062001.1. NC_006087.1.

Genome annotation databases

EnsemblBacteriaiAAT88896; AAT88896; Lxx10340.
GeneIDi2939106.
KEGGilxx:Lxx10340.
PATRICi22335626. VBILeiXyl11655_1067.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016822 Genomic DNA. Translation: AAT88896.1 .
RefSeqi YP_062001.1. NC_006087.1.

3D structure databases

ProteinModelPortali Q6AFE9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 281090.Lxx10340.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAT88896 ; AAT88896 ; Lxx10340 .
GeneIDi 2939106.
KEGGi lxx:Lxx10340.
PATRICi 22335626. VBILeiXyl11655_1067.

Phylogenomic databases

HOGENOMi HOG000031444.
KOi K01775.
OMAi TIADEMV.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci LXYL281090:GH0X-964-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 2 hits.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CTCB07Imported.

Entry informationi

Entry nameiQ6AFE9_LEIXX
AccessioniPrimary (citable) accession number: Q6AFE9
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2004
Last sequence update: September 13, 2004
Last modified: July 9, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi