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Q6AFE9 (Q6AFE9_LEIXX) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP-Rule MF_01201
EC=5.1.1.1 HAMAP-Rule MF_01201
Gene names
Name:alr EMBL AAT88896.1
Ordered Locus Names:Lxx10340 EMBL AAT88896.1
OrganismLeifsonia xyli subsp. xyli (strain CTCB07) [Complete proteome] [HAMAP] EMBL AAT88896.1
Taxonomic identifier281090 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Microbacteriaceae › Leifsonia ›

Protein attributes

Sequence length370 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. SAAS SAAS020622 HAMAP-Rule MF_01201

Cofactor

Pyridoxal phosphate By similarity. SAAS SAAS020622 HAMAP-Rule MF_01201

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622 HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201

Ontologies

Keywords
   LigandPyridoxal phosphate SAAS SAAS020622 HAMAP-Rule MF_01201
   Molecular functionIsomerase SAAS SAAS020622 HAMAP-Rule MF_01201
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-alanine biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionalanine racemase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site421Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Binding site1381Substrate By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue421N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
Q6AFE9 [UniParc].

Last modified September 13, 2004. Version 1.
Checksum: F8CE95A4718944CC

FASTA37038,420
        10         20         30         40         50         60 
MTIVDAVAEP LPRAVVDLAA LRRNVATLTR LIAPAETMLA VKADAYGHGL LPIAEAGVQA 

        70         80         90        100        110        120 
GATSLAVLEI SAGLVLRRAG VTVPLLAWLH GTGTDWRAGI ENDIQLGISA RWQLEAIAAA 

       130        140        150        160        170        180 
AADRAAIVHL KVDTGLSRNG ATREEWPALV DAALALQETG VVRLRAAWSH LADASIADDE 

       190        200        210        220        230        240 
AALAEFREAV AEAEARGARF EMLHLAASSA GIRMPEARFA LVRFGIAAYG LSPFDDTTGA 

       250        260        270        280        290        300 
ELGLRPVMRL EAPVIAVHVD GTTHVRLGIG FADGVPTLGL ARTSVLLGGR RCPVIAVEAD 

       310        320        330        340        350        360 
AMLVDAGAQR VERGDTAVLF GPGDSGEATA EEYAEWAGTI ADEMVTGVAA RVPRVYVGDD 

       370 
EGAGLTGTRG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE016822 Genomic DNA. Translation: AAT88896.1.
RefSeqYP_062001.1. NC_006087.1.

3D structure databases

ProteinModelPortalQ6AFE9.
ModBaseSearch...

Protein-protein interaction databases

STRING281090.Lxx10340.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAT88896; AAT88896; Lxx10340.
GeneID2939106.
KEGGlxx:Lxx10340.
PATRIC22335626. VBILeiXyl11655_1067.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000031444.
KOK01775.
OMADHEWIAT.

Enzyme and pathway databases

BioCycLXYL281090:GH0X-964-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 2 hits.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ6AFE9_LEIXX
AccessionPrimary (citable) accession number: Q6AFE9
Entry history
Integrated into UniProtKB/TrEMBL: September 13, 2004
Last sequence update: September 13, 2004
Last modified: May 29, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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