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Q6AF44

- PGK_LEIXX

UniProt

Q6AF44 - PGK_LEIXX

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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Leifsonia xyli subsp. xyli (strain CTCB07)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei37 – 371SubstrateUniRule annotation
Binding sitei119 – 1191SubstrateUniRule annotation
Binding sitei156 – 1561SubstrateUniRule annotation
Binding sitei206 – 2061ATPUniRule annotation
Binding sitei302 – 3021ATP; via carbonyl oxygenUniRule annotation
Binding sitei333 – 3331ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi359 – 3624ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciLXYL281090:GH0X-1081-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:Lxx11530
OrganismiLeifsonia xyli subsp. xyli (strain CTCB07)
Taxonomic identifieri281090 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrobacteriaceaeLeifsonia
ProteomesiUP000001306: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 403403Phosphoglycerate kinasePRO_0000145957Add
BLAST

Proteomic databases

PRIDEiQ6AF44.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi281090.Lxx11530.

Structurei

3D structure databases

ProteinModelPortaliQ6AF44.
SMRiQ6AF44. Positions 4-402.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni22 – 243Substrate bindingUniRule annotation
Regioni60 – 634Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiHASVYDI.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6AF44-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALRTLDSLG SLAGKRVVVR CDLNVPLKDG KITDDGRVRA SIPTLHALIA
60 70 80 90 100
QGAKVAIVSH LGRPEGAPDA QYSLAPVAQR LSELLGKPVT FASDTVGAGA
110 120 130 140 150
AEAVSGLEDG DVALLENLRF NPGETSKDEG EREAFAAELA AFGDAFVSDG
160 170 180 190 200
FGVVHRKQAS VYELAKALPS AAGALIATEL DVLDRLTENP ERPYTVLLGG
210 220 230 240 250
SKVSDKLGVI GHLLPRVDSL LIGGGMLFTF LAALGHRVGS SLLEADQIGT
260 270 280 290 300
VKGYLEQAKQ LGVEIVLPRD VVVASRFGVD AEHLVRPVDR IEDTGWGTSG
310 320 330 340 350
LGLDIGPETA EVFSERIRAA RTVFWNGPMG VFELAPFAAG TKAVAQALTE
360 370 380 390 400
VDGLGVVGGG DSAAAVHALG FSDDQFGHIS TGGGASLEFL EGKRLPGLEV

LGW
Length:403
Mass (Da):41,900
Last modified:September 13, 2004 - v1
Checksum:i3DCC1BF68C892355
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016822 Genomic DNA. Translation: AAT89001.1.
RefSeqiYP_062106.1. NC_006087.1.

Genome annotation databases

EnsemblBacteriaiAAT89001; AAT89001; Lxx11530.
GeneIDi2940304.
KEGGilxx:Lxx11530.
PATRICi22335884. VBILeiXyl11655_1191.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016822 Genomic DNA. Translation: AAT89001.1 .
RefSeqi YP_062106.1. NC_006087.1.

3D structure databases

ProteinModelPortali Q6AF44.
SMRi Q6AF44. Positions 4-402.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 281090.Lxx11530.

Proteomic databases

PRIDEi Q6AF44.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAT89001 ; AAT89001 ; Lxx11530 .
GeneIDi 2940304.
KEGGi lxx:Lxx11530.
PATRICi 22335884. VBILeiXyl11655_1191.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227107.
KOi K00927.
OMAi HASVYDI.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci LXYL281090:GH0X-1081-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CTCB07.

Entry informationi

Entry nameiPGK_LEIXX
AccessioniPrimary (citable) accession number: Q6AF44
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 2, 2005
Last sequence update: September 13, 2004
Last modified: October 29, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3