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Q6AD34

- Q6AD34_LEIXX

UniProt

Q6AD34 - Q6AD34_LEIXX

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Protein
Alanine racemase
Gene
alr, Lxx19950
Organism
Leifsonia xyli subsp. xyli (strain CTCB07)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei36 – 361Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei132 – 1321Substrate By similarityUniRule annotation
Active sitei262 – 2621Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei310 – 3101Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotations

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciLXYL281090:GH0X-1882-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
Ordered Locus Names:Lxx19950Imported
OrganismiLeifsonia xyli subsp. xyli (strain CTCB07)Imported
Taxonomic identifieri281090 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrobacteriaceaeLeifsonia
ProteomesiUP000001306: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei36 – 361N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi281090.Lxx19950.

Structurei

3D structure databases

ProteinModelPortaliQ6AD34.

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000031444.
KOiK01775.
OMAiKSNTIPW.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6AD34-1 [UniParc]FASTAAdd to Basket

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MSAPFRELVV DLDAVSANVV RLRERAGTPH LMAVVKADAY GHGAVESACA    50
ALAGGADWLG VADLSEASQL RAAGIEAPLL AWLHDPDEDF VAAIAAGVDI 100
GVSSLAHLEA AAAAGGGSPA FVQLKLETGL SRNGLPEEQW EAVFARAHEL 150
ERSGRIVVRG VFSHLSNASP AEDRAAIAAY ERGLARAEAA GLAPELRHIA 200
ASAAAISLPE ARFTLVRLGL AIYGLSPFGA ASATELGLRP ALTLRARVAA 250
VRRVPAGKGV SYDYTYRTER ETTLALVPVG YGDGLPRHAS NLGPVSIGGE 300
RFRVSGRIAM DQFVVDVGDA PVAVGDEVVL FGDPARGVPG ADDWAAAAET 350
INYEIVTRLG GRLRRTFRGG PA 372
Length:372
Mass (Da):38,661
Last modified:September 13, 2004 - v1
Checksum:iC8BB640AA257008F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016822 Genomic DNA. Translation: AAT89710.1.
RefSeqiYP_062815.1. NC_006087.1.

Genome annotation databases

EnsemblBacteriaiAAT89710; AAT89710; Lxx19950.
GeneIDi2940269.
KEGGilxx:Lxx19950.
PATRICi22337666. VBILeiXyl11655_2070.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016822 Genomic DNA. Translation: AAT89710.1 .
RefSeqi YP_062815.1. NC_006087.1.

3D structure databases

ProteinModelPortali Q6AD34.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 281090.Lxx19950.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAT89710 ; AAT89710 ; Lxx19950 .
GeneIDi 2940269.
KEGGi lxx:Lxx19950.
PATRICi 22337666. VBILeiXyl11655_2070.

Phylogenomic databases

HOGENOMi HOG000031444.
KOi K01775.
OMAi KSNTIPW.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci LXYL281090:GH0X-1882-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CTCB07Imported.

Entry informationi

Entry nameiQ6AD34_LEIXX
AccessioniPrimary (citable) accession number: Q6AD34
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2004
Last sequence update: September 13, 2004
Last modified: July 9, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi