Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Inorganic pyrophosphatase

Gene

ppa

Organism
Leifsonia xyli subsp. xyli (strain CTCB07)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.UniRule annotation

Catalytic activityi

Diphosphate + H2O = 2 phosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi9Magnesium 2UniRule annotation1
Binding sitei17SubstrateUniRule annotation1
Binding sitei31SubstrateUniRule annotation1
Binding sitei43SubstrateUniRule annotation1
Metal bindingi53Magnesium 1UniRule annotation1
Metal bindingi58Magnesium 1UniRule annotation1
Metal bindingi58Magnesium 2UniRule annotation1
Metal bindingi85Magnesium 3UniRule annotation1
Active sitei90Proton acceptorUniRule annotation1
Metal bindingi90Magnesium 1UniRule annotation1
Metal bindingi90Magnesium 3UniRule annotation1
Binding sitei127SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandMagnesium, Metal-binding

Enzyme and pathway databases

BioCyciLXYL281090:G1G06-2174-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Inorganic pyrophosphataseUniRule annotation (EC:3.6.1.1UniRule annotation)
Alternative name(s):
Pyrophosphate phospho-hydrolaseUniRule annotation
Short name:
PPaseUniRule annotation
Gene namesi
Name:ppaUniRule annotation
Ordered Locus Names:Lxx21530
OrganismiLeifsonia xyli subsp. xyli (strain CTCB07)
Taxonomic identifieri281090 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesMicrobacteriaceaeLeifsonia
Proteomesi
  • UP000001306 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001375041 – 163Inorganic pyrophosphataseAdd BLAST163

Interactioni

Subunit structurei

Homohexamer.UniRule annotation

Protein-protein interaction databases

STRINGi281090.Lxx21530

Structurei

3D structure databases

ProteinModelPortaliQ6ACP7
SMRiQ6ACP7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PPase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105F0N Bacteria
COG0221 LUCA
HOGENOMiHOG000236473
KOiK01507
OMAiDEPTFPG
OrthoDBiPOG091H05Q5

Family and domain databases

CDDicd00412 pyrophosphatase, 1 hit
Gene3Di3.90.80.101 hit
HAMAPiMF_00209 Inorganic_PPase, 1 hit
InterProiView protein in InterPro
IPR008162 Pyrophosphatase
IPR036649 Pyrophosphatase_sf
PANTHERiPTHR10286 PTHR10286, 1 hit
PfamiView protein in Pfam
PF00719 Pyrophosphatase, 1 hit
SUPFAMiSSF50324 SSF50324, 1 hit
PROSITEiView protein in PROSITE
PS00387 PPASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q6ACP7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAYDVVIEI PKGSRNKYEV DHETGRVYLD RVLFTAFVYP ADYGFFENTL
60 70 80 90 100
GDDGDPLDVL VLLEYPVFPG VGIKVRPVGV LKMSDEAGGD AKIIAVQHKD
110 120 130 140 150
PRWQHIQDVN DIPEYTRKEI EHFFARYKDL EPGKFVTIEG WGDAAEAEKI
160
VQAGFANLEA QGH
Length:163
Mass (Da):18,358
Last modified:September 13, 2004 - v1
Checksum:i9091CA4515E821F1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016822 Genomic DNA Translation: AAT89846.1
RefSeqiWP_011186830.1, NC_006087.1

Genome annotation databases

EnsemblBacteriaiAAT89846; AAT89846; Lxx21530
KEGGilxx:Lxx21530

Similar proteinsi

Entry informationi

Entry nameiIPYR_LEIXX
AccessioniPrimary (citable) accession number: Q6ACP7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 2, 2005
Last sequence update: September 13, 2004
Last modified: February 28, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome