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Reviewed, UniProtKB/Swiss-Prot Q6AC27 (IOLG_LEIXX)

Last modified January 19, 2010. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Inositol 2-dehydrogenase
    EC=1.1.1.18
Alternative name(s):
    Myo-inositol 2-dehydrogenase
      Short name=MI 2-dehydrogenase
Gene names
Name: iolG
Ordered Locus Names: Lxx24320
OrganismLeifsonia xyli subsp. xyli [Complete proteome] [HAMAP]
Taxonomic identifier59736 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrobacteriaceaeLeifsonia

Protein attributes

Sequence length339 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose) By similarity. HAMAP MF_01671

Catalytic activity

Myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH. HAMAP MF_01671

Subunit structure

Homotetramer By similarity. HAMAP MF_01671

Sequence similarities

Belongs to the gfo/idh/mocA family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processinositol catabolic process

Inferred from electronic annotation. Source: HAMAP

oxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionbinding

Inferred from electronic annotation. Source: InterPro

inositol 2-dehydrogenase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 339339Inositol 2-dehydrogenase HAMAP MF_01671
PRO_0000352574

Sequences

Sequence LengthMass (Da)Tools
Q6AC27-1 [UniParc].

Last modified September 13, 2004. Version 1.
Checksum: B2C2B50874FB1C9C

FASTA33936,423
        10         20         30         40         50         60 
MTTTPDLRVG VGGAGQMGAD HIQRITRVIS GATVSAIVEP DAGRAAAAAA APGSRAFASL 

        70         80         90        100        110        120 
DDALDASALE AVVIATPGQF HELVLVPALA AGLPVLCEKP LTPDSAEALR VLELEQTLDR 

       130        140        150        160        170        180 
PHIQLGFMRR FDDEYRALRE LVVSGDAGEL LFLRGVHRNP SVPESYTQSM LITDSVVHEF 

       190        200        210        220        230        240 
DVMPWLAGSP VASVEVKYPR RNDRAPERLR EPILVLIELR NGVLVDVEMN VSVRFGYQVA 

       250        260        270        280        290        300 
TEAVFQTGTA RIGQPAGLQR WSDARFSIAE HTSFTTRFAR AYDAQVQAWV DAVRDGSLVA 

       310        320        330 
GPNAWDGYLV ALACEAGVRA LSEPGPIAFA PAERPAFYA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016822 Genomic DNA. Translation: AAT90065.1.
RefSeqYP_063170.1.

3D structure databases

SMRQ6AC27. Positions 8-328.
ModBaseSearch...

Genome annotation databases

GeneID2939273.
GenomeReviewsGene locus Lxx24320 in contig AE016822_GR.
KEGGlxx:Lxx24320.
NMPDRfig|281090.3.peg.1957.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG612336.
OMAFGYQVAT.

Enzyme and pathway databases

BioCycLXYL281090:LXX24320-MONOMER.

Family and domain databases

HAMAPMF_01671. IolG.
[Tree]
InterProIPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PfamPF01408. GFO_IDH_MocA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameIOLG_LEIXX
AccessionPrimary (citable) accession number: Q6AC27
Entry history
Integrated into UniProtKB/Swiss-Prot: October 14, 2008
Last sequence update: September 13, 2004
Last modified: January 19, 2010
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents