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Protein

Putative fluoride ion transporter CrcB 1

Gene

crcB1

Organism
Propionibacterium acnes (strain KPA171202 / DSM 16379)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Important for reducing fluoride concentration in the cell, thus reducing its toxicity.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciPACN267747:GHO9-779-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative fluoride ion transporter CrcB 1UniRule annotation
Gene namesi
Name:crcB1UniRule annotation
Ordered Locus Names:PPA0770
OrganismiPropionibacterium acnes (strain KPA171202 / DSM 16379)
Taxonomic identifieri267747 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaPropionibacterialesPropionibacteriaceaePropionibacterium
Proteomesi
  • UP000000603 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei13 – 3321HelicalUniRule annotationAdd
BLAST
Transmembranei42 – 6221HelicalUniRule annotationAdd
BLAST
Transmembranei80 – 10021HelicalUniRule annotationAdd
BLAST
Transmembranei111 – 13121HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 143143Putative fluoride ion transporter CrcB 1PRO_0000110149Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi267747.PPA0770.

Family & Domainsi

Sequence similaritiesi

Belongs to the CrcB (TC 9.B.71) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG41085J0. Bacteria.
ENOG41128KT. LUCA.
HOGENOMiHOG000052573.
KOiK06199.
OMAiLINWIGC.

Family and domain databases

HAMAPiMF_00454. CrcB. 1 hit.
InterProiIPR003691. CrcB.
[Graphical view]
PfamiPF02537. CRCB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6A9P0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMRSGFLDR RPVLVGLVFL GGCLGTLIRS VIAHAWPSRA DGVPWGTLAI
60 70 80 90 100
NLVGAFVLAT LLELLVHAGP DRGVRRAVRL CIGTGLLGGF TTYSALTVEA
110 120 130 140
GQRVMSGQWL WGIAYLLTSV AAGALLAWVV IAAVRCVMGK RSS
Length:143
Mass (Da):15,060
Last modified:September 13, 2004 - v1
Checksum:i8E682FA74A94C848
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017283 Genomic DNA. Translation: AAT82526.1.
RefSeqiWP_002523752.1. NC_006085.1.

Genome annotation databases

EnsemblBacteriaiAAT82526; AAT82526; PPA0770.
GeneIDi2931298.
KEGGipac:PPA0770.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017283 Genomic DNA. Translation: AAT82526.1.
RefSeqiWP_002523752.1. NC_006085.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi267747.PPA0770.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT82526; AAT82526; PPA0770.
GeneIDi2931298.
KEGGipac:PPA0770.

Phylogenomic databases

eggNOGiENOG41085J0. Bacteria.
ENOG41128KT. LUCA.
HOGENOMiHOG000052573.
KOiK06199.
OMAiLINWIGC.

Enzyme and pathway databases

BioCyciPACN267747:GHO9-779-MONOMER.

Family and domain databases

HAMAPiMF_00454. CrcB. 1 hit.
InterProiIPR003691. CrcB.
[Graphical view]
PfamiPF02537. CRCB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCRCB1_PROAC
AccessioniPrimary (citable) accession number: Q6A9P0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: September 13, 2004
Last modified: September 7, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.