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Q6A8Q7 (GLGB_PROAC) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
1,4-alpha-glucan branching enzyme GlgB

EC=2.4.1.18
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name=BE
Gene names
Name:glgB
Ordered Locus Names:PPA1111
OrganismPropionibacterium acnes (strain KPA171202 / DSM 16379) [Complete proteome] [HAMAP]
Taxonomic identifier267747 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesPropionibacterineaePropionibacteriaceaePropionibacterium

Protein attributes

Sequence length644 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity. HAMAP-Rule MF_00685

Catalytic activity

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain. HAMAP-Rule MF_00685

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00685

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00685

Sequence similarities

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 6446441,4-alpha-glucan branching enzyme GlgB HAMAP-Rule MF_00685
PRO_0000188726

Sites

Active site3091Nucleophile By similarity
Active site3621Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6A8Q7 [UniParc].

Last modified September 13, 2004. Version 1.
Checksum: 4DB81FCC695512AC

FASTA64473,563
        10         20         30         40         50         60 
MAHDEFGGLT GWDLEGFHSG GDTEVWKRLG SHVVTIDDDE RGPITGTRFA VWAPNAQAVE 

        70         80         90        100        110        120 
VISDFNWWTG DRMRLIPGSG VWGTFVEGVD EGTLYKFRIQ DQWGTWHEKV DPMARYSEQA 

       130        140        150        160        170        180 
PQNASIVTET HYEWNDDEWI ARREASRAHA EPMSVYEVHL GGWRHGLSYR ELADQLVSYV 

       190        200        210        220        230        240 
TWQGYTHVEF MPLAEHPFAP SWGYQVTGYF SPTSRYGSPD DLRYLIDKLH QAGIGVIMDW 

       250        260        270        280        290        300 
VPGHFPKDDW ALGRFDGTAL YEHADPRQGE HKDWGTYIFN YGRNEVKSFL VSSALYWISE 

       310        320        330        340        350        360 
FHADGLRVDA VASMLYLDYS REEGQWVPNK YGGRENLEAI DFLRYVNSHL YSRHPGILMI 

       370        380        390        400        410        420 
AEESTSFPGV TKPVDDGGLG FGFKWNMGWM NDSLRYLELN PFHRQYHHGE MTFAMVYQYS 

       430        440        450        460        470        480 
ENFILPISHD EVVHGKGSMI TKIPGDDWQQ FASLRAFYSY MWSFPGKQLV FMGQEFGQRH 

       490        500        510        520        530        540 
EFDESVSLEW FVADLWGHGG LKRLFRDLNK IYKENPALWQ LDSDPRGFEW INADDAGNNL 

       550        560        570        580        590        600 
FSWLRRSDDG STIACFTNFS PNPQTDYRID LPMEGVWTEI LNTDSLEYDG TGEFGNLGQI 

       610        620        630        640 
VAAPLPAPDR LRAVATVCVP PMGSVWLRHN PSATAALPGD PGVQ 

« Hide

References

[1]"The complete genome sequence of Propionibacterium acnes, a commensal of human skin."
Brueggemann H., Henne A., Hoster F., Liesegang H., Wiezer A., Strittmatter A., Hujer S., Duerre P., Gottschalk G.
Science 305:671-673(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KPA171202 / DSM 16379.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017283 Genomic DNA. Translation: AAT82859.1.
RefSeqYP_055817.1. NC_006085.1.

3D structure databases

ProteinModelPortalQ6A8Q7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING267747.PPA1111.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAT82859; AAT82859; PPA1111.
GeneID2930991.
KEGGpac:PPA1111.
PATRIC23036961. VBIProAcn64440_1149.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0296.
HOGENOMHOG000283037.
KOK00700.
OMAITASRYL.
OrthoDBEOG6JX7GT.

Enzyme and pathway databases

BioCycPACN267747:GHO9-1123-MONOMER.
UniPathwayUPA00164.

Family and domain databases

Gene3D2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPMF_00685. GlgB.
InterProIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERPTHR10357. PTHR10357. 1 hit.
PfamPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFPIRSF000463. GlgB. 1 hit.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 1 hit.
TIGRFAMsTIGR01515. branching_enzym. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGB_PROAC
AccessionPrimary (citable) accession number: Q6A8Q7
Entry history
Integrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: September 13, 2004
Last modified: June 11, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries