Q6A7J8 (EFTS_PROAC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Elongation factor Ts
Short name=EF-Ts

Gene names

Name:	tsf
Ordered Locus Names:	PPA1520

Organism

Propionibacterium acnes (strain KPA171202 / DSM 16379) [Complete proteome] [HAMAP]

Taxonomic identifier

267747 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Propionibacterineae › Propionibacteriaceae › Propionibacterium

Protein attributes

Sequence length	270 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. HAMAP MF_00050
Subcellular location	Cytoplasm HAMAP MF_00050.
Sequence similarities	Belongs to the EF-Ts family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Elongation factor
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	translation elongation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 270	270	Elongation factor Ts HAMAP MF_00050		PRO_0000161172
Regions
	Region	75 – 78	4	Involved in Mg(2+) ion dislocation from EF-Tu By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6A7J8 [UniParc]. Last modified September 13, 2004. Version 1. Checksum: C45B889F54716C62	FASTA	270	28,488
	10 20 30 40 50 60 MAITAAEVKK LRDATGAGMM DAKKALTEAD GDFDKAVDIL RVSGAAKAAK RSDREASNGL 70 80 90 100 110 120 VAAAGSSLVH IGSETDFVAK NEEFIAAAHE IAEAADKAGA DSKDAANAAA LADGTTVGDK 130 140 150 160 170 180 LGELAAKIGE KIELANAAHF DGNAHVYLHR RSQDLPPQVG VMVEYEGDNI EAVHGVCLQI 190 200 210 220 230 240 AAMSPRWLSR DEVPADVVEH ERTVAADIAR EEGKPEKIID RIVEGRLGGF FKENCLLDQP 250 260 270 AISDDKKTVA QTLEAAGVTL KRFVRFSAGE

References

[1]

"The complete genome sequence of Propionibacterium acnes, a commensal of human skin." Brueggemann H., Henne A., Hoster F., Liesegang H., Wiezer A., Strittmatter A., Hujer S., Duerre P., Gottschalk G. Science 305:671-673(2004) [PubMed: 15286373] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KPA171202 / DSM 16379.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017283 Genomic DNA. Translation: AAT83267.1.
RefSeq	YP_056225.1. NC_006085.1.
3D structure databases
ProteinModelPortal	Q6A7J8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2931532.
GenomeReviews	Gene locus PPA1520 in contig AE017283_GR.
KEGG	pac:PPA1520.
NMPDR	fig|267747.1.peg.1502.
PATRIC	23037813. VBIProAcn64440_1565.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG713289.
OMA	YLHGTRI.
PhylomeDB	Q6A7J8.
ProtClustDB	PRK09377.
Enzyme and pathway databases
BioCyc	PACN267747:PPA1520-MONOMER.
Family and domain databases
HAMAP	MF_00050. EF_Ts. [Tree]
InterPro	IPR001816. Transl_elong_EFTs/EF1B. IPR014039. Transl_elong_EFTs/EF1B_dimer. IPR018101. Transl_elong_Ts_CS. IPR009060. UBA-like. IPR000449. UBA/transl_elong_EF1B_N. [Graphical view]
Gene3D	G3DSA:3.30.479.20. Transl_elong_EFTs/EF1B_dimer. 3 hits.
KO	K02357.
PANTHER	PTHR11741. Transl_elong_EFTs/EF1B. 1 hit.
Pfam	PF00889. EF_TS. 1 hit. PF00627. UBA. 1 hit. [Graphical view]
SUPFAM	SSF54713. EF_TS. 1 hit. SSF46934. UBA_like. 1 hit.
TIGRFAMs	TIGR00116. Tsf. 1 hit.
PROSITE	PS01126. EF_TS_1. 1 hit. PS01127. EF_TS_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EFTS_PROAC

Accession

Primary (citable) accession number: Q6A7J8

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 2005
Last sequence update:	September 13, 2004
Last modified:	January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program