Reviewed,
UniProtKB/Swiss-Prot Q6A780 (DNAE2_PROAC)
Last modified
July 22, 2008.
Version 29.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Error-prone DNA polymerase EC=2.7.7.7 | ||||
| Gene names |
| ||||
| Organism | Propionibacterium acnes [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 1747 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Propionibacterineae › Propionibacteriaceae › Propionibacterium |
Protein attributes
| Sequence length | 1134 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. |
| Catalytic activity | Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). |
| Subcellular location | CytoplasmProbable. |
| Sequence similarities | Belongs to the DNA polymerase type-C family. DnaE2 subfamily. |
Ontologies
Keywords | |
|---|---|
| Biological process | DNA damage DNA repair DNA replication |
| Cellular component | Cytoplasm |
| Molecular function | DNA-directed DNA polymerase Nucleotidyltransferase Transferase |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Biological process | error-prone DNA repair Inferred from electronic annotation. Source: HAMAP |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: HAMAP |
| Molecular function | DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 1134 | 1134 | Error-prone DNA polymerase | PRO_0000103387 | |||
Sequences
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References
| [1] | "The complete genome sequence of Propionibacterium acnes, a commensal of human skin." Brueggemann H., Henne A., Hoster F., Liesegang H., Wiezer A., Strittmatter A., Hujer S., Duerre P., Gottschalk G. Science 305:671-673(2004) [PubMed: 15286373] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KPA171202 / DSM 16379. |
Cross-references
Sequence databases | |
|---|---|
| AE017283 Genomic DNA. Translation: AAT83385.1. | |
| RefSeq | YP_056343.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 2931181. |
| GenomeReviews | Gene locus PPA1650 in contig AE017283_GR. |
| KEGG | pac:PPA1650. |
| NMPDR | fig|267747.1.peg.1620. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q6A780. |
Enzyme and pathway databases | |
| BioCyc | PACN267747:PPA1650-MON. |
Family and domain databases | |
| HAMAP | MF_01902. [Tree] |
| InterPro | IPR011708. DNA_pol3_alpha. IPR004365. NA_bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. PHP_N. IPR004805. PolC_alpha. [Graphical view] |
| Pfam | PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view] |
| SMART | SM00481. POLIIIAc. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR00594. polc. 1 hit. |
| BLOCKS | Search... |
| ProtoNet | Search... |
Entry information
| Entry name | DNAE2_PROAC | ||||||||
| Accession | Primary (citable) accession number: Q6A780 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||

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