Q6A6V2 (GCP_PROAC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	PPA1782

Organism

Propionibacterium acnes (strain KPA171202 / DSM 16379) [Complete proteome] [HAMAP]

Taxonomic identifier

267747 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Propionibacterineae › Propionibacteriaceae › Propionibacterium

Protein attributes

Sequence length	347 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 347	347	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303487

Sequences

	Sequence		Length	Mass (Da)
	Q6A6V2 [UniParc]. Last modified September 13, 2004. Version 1. Checksum: 90E29D626371006F	FASTA	347	35,996
	10 20 30 40 50 60 MSEPLILGIE SSCDETGVGI VRGNDLLANE VASSMEQHVR FGGVVPEVAS RAHLEAIVPV 70 80 90 100 110 120 LDKAASTAGV DLSELDGIAV TAGPGLAGAL VVGLSAAKAL ASWLNKPLYG VNHLAGHVAV 130 140 150 160 170 180 DLLEHGELPM PCGALLVSGG HTSLLWVNDI ATDIIEVGST IDDAAGEAYD KVARVLGLPY 190 200 210 220 230 240 PGGPVIDKAA AEGDPTAIRF PRGLTARHDM VKHRFDYSFS GLKTAVSRWV ETQQRDGVEF 250 260 270 280 290 300 RIADVAASFQ EAVADVLTAK AVDMCQEYGL THFLIGGGVA ANSRLRTLLA ERMADAGVEL 310 320 330 340 RRPRPGLCTD NGAMIAALGV QVVKAGLPAS AMDISADSGL PIETVLV

References

[1]

"The complete genome sequence of Propionibacterium acnes, a commensal of human skin." Brueggemann H., Henne A., Hoster F., Liesegang H., Wiezer A., Strittmatter A., Hujer S., Duerre P., Gottschalk G. Science 305:671-673(2004) [PubMed: 15286373] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KPA171202 / DSM 16379.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017283 Genomic DNA. Translation: AAT83511.1.
RefSeq	YP_056469.1. NC_006085.1.
3D structure databases
ProteinModelPortal	Q6A6V2.
ModBase	Search...
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2932649.
GenomeReviews	Gene locus PPA1782 in contig AE017283_GR.
KEGG	pac:PPA1782.
NMPDR	fig|267747.1.peg.1746.
PATRIC	23038383. VBIProAcn64440_1841.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304663.
OMA	PLYGVNH.
PhylomeDB	Q6A6V2.
ProtClustDB	CLSK2764175.
Enzyme and pathway databases
BioCyc	PACN267747:PPA1782-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_PROAC

Accession

Primary (citable) accession number: Q6A6V2

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	September 13, 2004
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program