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Q6A5X5

- G6PI_PROAC

UniProt

Q6A5X5 - G6PI_PROAC

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Propionibacterium acnes (strain KPA171202 / DSM 16379)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei369 – 3691Proton donorUniRule annotation
Active sitei400 – 4001UniRule annotation
Active sitei524 – 5241UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciPACN267747:GHO9-2137-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:PPA2131
OrganismiPropionibacterium acnes (strain KPA171202 / DSM 16379)
Taxonomic identifieri267747 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesPropionibacterineaePropionibacteriaceaePropionibacterium
ProteomesiUP000000603: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 560560Glucose-6-phosphate isomerasePRO_0000180707Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi267747.PPA2131.

Structurei

3D structure databases

ProteinModelPortaliQ6A5X5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiMIALTHY.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6A5X5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPTLIDATST PAWGTLSGLK SRFADGPHKL RRLFDADPHR AERYTLDVAD
60 70 80 90 100
LHVDLSKNLL TDEIRDALLE LAAQMRVTER RDAMYAGEHI NVTEDRAVLH
110 120 130 140 150
TALRRSRTDE LHVDGQDAVA DVHEVLDKIY AFADKVRSGE WKGVTGKPIR
160 170 180 190 200
TVINVGIGGS DLGPVMAYEA LKPYVKDGLE CRFISNIDPT DAAVKTADLD
210 220 230 240 250
PETTLVIIAS KTFTTLETLT NARCVRAWLL DGLVAAGAIS DTEQARRDAV
260 270 280 290 300
AKHFVAVSTA LDKVEEFGID PVNAFGFWSW VGGRYSVDSA VGTSLAVAIG
310 320 330 340 350
PKGFEDFLAG FHAVDEHFAT AEPERNVPLF MGLLNIWYTN FWDAHSHAVL
360 370 380 390 400
PYSQYLHRFP AYLQQLTMES NGKSVRWDGS AVTTDTGEIF WGEPGTNGQH
410 420 430 440 450
AFYQLIHQGT RVIPADFIAV ANPVHPTKDG GTDVHELFLS NFFAQTAALA
460 470 480 490 500
FGKTADEVRA EGTDEAIVPA RVFAGDRPTT SIMADELSPK VLGELIALYE
510 520 530 540 550
HITFVQGVVW GIDSFDQWGV ELGKKLALQI APAVSGNDEA LATQDPSTQG
560
LVTWYREHRR
Length:560
Mass (Da):61,457
Last modified:September 13, 2004 - v1
Checksum:i7DB374E911211615
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017283 Genomic DNA. Translation: AAT83838.1.
RefSeqiYP_056796.1. NC_006085.1.

Genome annotation databases

EnsemblBacteriaiAAT83838; AAT83838; PPA2131.
GeneIDi2932472.
KEGGipac:PPA2131.
PATRICi23039089. VBIProAcn64440_2185.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017283 Genomic DNA. Translation: AAT83838.1 .
RefSeqi YP_056796.1. NC_006085.1.

3D structure databases

ProteinModelPortali Q6A5X5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 267747.PPA2131.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAT83838 ; AAT83838 ; PPA2131 .
GeneIDi 2932472.
KEGGi pac:PPA2131.
PATRICi 23039089. VBIProAcn64440_2185.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OMAi MIALTHY.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci PACN267747:GHO9-2137-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete genome sequence of Propionibacterium acnes, a commensal of human skin."
    Brueggemann H., Henne A., Hoster F., Liesegang H., Wiezer A., Strittmatter A., Hujer S., Duerre P., Gottschalk G.
    Science 305:671-673(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KPA171202 / DSM 16379.

Entry informationi

Entry nameiG6PI_PROAC
AccessioniPrimary (citable) accession number: Q6A5X5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: September 13, 2004
Last modified: October 29, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3