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Protein

Uronate isomerase

Gene

uxaC

Organism
Cutibacterium acnes (strain DSM 16379 / KPA171202) (Propionibacterium acnes)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase

Enzyme and pathway databases

BioCyciPACN267747:G1G0Y-2535-MONOMER
UniPathwayiUPA00246

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:PPA2329
OrganismiCutibacterium acnes (strain DSM 16379 / KPA171202) (Propionibacterium acnes)
Taxonomic identifieri267747 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaPropionibacterialesPropionibacteriaceaeCutibacterium
Proteomesi
  • UP000000603 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001727801 – 470Uronate isomeraseAdd BLAST470

Interactioni

Protein-protein interaction databases

STRINGi267747.PPA2329

Structurei

3D structure databases

ProteinModelPortaliQ6A5D0
SMRiQ6A5D0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2H Bacteria
COG1904 LUCA
HOGENOMiHOG000238114
KOiK01812
OMAiFREMTTE

Family and domain databases

HAMAPiMF_00675 UxaC, 1 hit
InterProiView protein in InterPro
IPR032466 Metal_Hydrolase
IPR003766 Uronate_isomerase
PfamiView protein in Pfam
PF02614 UxaC, 1 hit
SUPFAMiSSF51556 SSF51556, 1 hit

Sequencei

Sequence statusi: Complete.

Q6A5D0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTPTLTLSE DRLLPRESSA LAAAREIYRS TKGLPIISPH GHVPVSWIAD
60 70 80 90 100
DMAFSDPTSL LITPDHYVNR LLHANGVDLE DLGVGRKTMS EEDNRRAFRI
110 120 130 140 150
LCEHWRDFAG TAMRYWLVDQ LIGIFGITER PSPENADRIY DTIAERIAQP
160 170 180 190 200
DFLPRALMDS FDIAFIATTD DPCDDLDGHA RLAADETFTR RVAPTFRPDK
210 220 230 240 250
YLEPAAGGWT GLLARLSEVS GCDATTLDGF TEAMEDRRAY FRQHGAVSSD
260 270 280 290 300
HSHRDLGTII LDHDRAASIF DASVAGRATV EEMALLRRHL FTDQARMASE
310 320 330 340 350
DGLTMTVHPA VHRNHDTAAF HRFGADIGSD VPVTLEVVDS LHPLLDKFGN
360 370 380 390 400
TDLKLVVFTI DETLYSREIA PLSGWYRSLY IGVPWWFIDA PESVMRFKHA
410 420 430 440 450
VTEMAGFSRV SGMIDDTRAF CSIPARHDMS RRLDAAHLAE LVVLGRLDLD
460 470
EAVEIAHRLV VEQPTQVFGL
Length:470
Mass (Da):52,493
Last modified:September 13, 2004 - v1
Checksum:i5115A1E18CA59D80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017283 Genomic DNA Translation: AAT84033.1
RefSeqiWP_002530879.1, NC_006085.1

Genome annotation databases

EnsemblBacteriaiAAT84033; AAT84033; PPA2329
GeneIDi2931777
KEGGipac:PPA2329
PATRICifig|267747.3.peg.2400

Similar proteinsi

Entry informationi

Entry nameiUXAC_CUTAK
AccessioniPrimary (citable) accession number: Q6A5D0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: September 13, 2004
Last modified: March 28, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health