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Protein

Uronate isomerase

Gene

uxaC

Organism
Propionibacterium acnes (strain KPA171202 / DSM 16379)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciPACN267747:GHO9-2339-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:PPA2329
OrganismiPropionibacterium acnes (strain KPA171202 / DSM 16379)
Taxonomic identifieri267747 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaPropionibacterialesPropionibacteriaceaePropionibacterium
Proteomesi
  • UP000000603 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 470470Uronate isomerasePRO_0000172780Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi267747.PPA2329.

Structurei

3D structure databases

ProteinModelPortaliQ6A5D0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000238114.
KOiK01812.
OMAiREMTTET.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6A5D0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTPTLTLSE DRLLPRESSA LAAAREIYRS TKGLPIISPH GHVPVSWIAD
60 70 80 90 100
DMAFSDPTSL LITPDHYVNR LLHANGVDLE DLGVGRKTMS EEDNRRAFRI
110 120 130 140 150
LCEHWRDFAG TAMRYWLVDQ LIGIFGITER PSPENADRIY DTIAERIAQP
160 170 180 190 200
DFLPRALMDS FDIAFIATTD DPCDDLDGHA RLAADETFTR RVAPTFRPDK
210 220 230 240 250
YLEPAAGGWT GLLARLSEVS GCDATTLDGF TEAMEDRRAY FRQHGAVSSD
260 270 280 290 300
HSHRDLGTII LDHDRAASIF DASVAGRATV EEMALLRRHL FTDQARMASE
310 320 330 340 350
DGLTMTVHPA VHRNHDTAAF HRFGADIGSD VPVTLEVVDS LHPLLDKFGN
360 370 380 390 400
TDLKLVVFTI DETLYSREIA PLSGWYRSLY IGVPWWFIDA PESVMRFKHA
410 420 430 440 450
VTEMAGFSRV SGMIDDTRAF CSIPARHDMS RRLDAAHLAE LVVLGRLDLD
460 470
EAVEIAHRLV VEQPTQVFGL
Length:470
Mass (Da):52,493
Last modified:September 13, 2004 - v1
Checksum:i5115A1E18CA59D80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017283 Genomic DNA. Translation: AAT84033.1.
RefSeqiWP_002530879.1. NC_006085.1.

Genome annotation databases

EnsemblBacteriaiAAT84033; AAT84033; PPA2329.
GeneIDi2931777.
KEGGipac:PPA2329.
PATRICi23039531. VBIProAcn64440_2400.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017283 Genomic DNA. Translation: AAT84033.1.
RefSeqiWP_002530879.1. NC_006085.1.

3D structure databases

ProteinModelPortaliQ6A5D0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi267747.PPA2329.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT84033; AAT84033; PPA2329.
GeneIDi2931777.
KEGGipac:PPA2329.
PATRICi23039531. VBIProAcn64440_2400.

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000238114.
KOiK01812.
OMAiREMTTET.

Enzyme and pathway databases

UniPathwayiUPA00246.
BioCyciPACN267747:GHO9-2339-MONOMER.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_PROAC
AccessioniPrimary (citable) accession number: Q6A5D0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: September 13, 2004
Last modified: September 7, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.