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Protein

Alpha-(1,3)-fucosyltransferase 11

Gene

fut11

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Probable fucosyltransferase.By similarity

Pathwayi: protein glycosylation

This protein is involved in the pathway protein glycosylation, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein glycosylation and in Protein modification.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

UniPathwayiUPA00378.

Protein family/group databases

CAZyiGT10. Glycosyltransferase Family 10.

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-(1,3)-fucosyltransferase 11 (EC:2.4.1.-)
Alternative name(s):
Fucosyltransferase XI
Short name:
Fuc-TXI
Short name:
FucT-XI
Galactoside 3-L-fucosyltransferase 11
Short name:
Fucosyltransferase 11
Gene namesi
Name:fut11
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-5933996. fut11.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2020CytoplasmicSequence analysisAdd
BLAST
Transmembranei21 – 3717Helical; Signal-anchor for type II membrane proteinSequence analysisAdd
BLAST
Topological domaini38 – 533496LumenalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 533533Alpha-(1,3)-fucosyltransferase 11PRO_0000299016Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi138 ↔ 143By similarity
Glycosylationi148 – 1481N-linked (GlcNAc...)Sequence analysis
Glycosylationi206 – 2061N-linked (GlcNAc...)Sequence analysis
Glycosylationi358 – 3581N-linked (GlcNAc...)Sequence analysis
Disulfide bondi429 ↔ 432By similarity
Glycosylationi511 – 5111N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ6A1G2.

Expressioni

Gene expression databases

BgeeiENSXETG00000015541.
ExpressionAtlasiQ6A1G2. baseline.

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000033891.

Structurei

3D structure databases

ProteinModelPortaliQ6A1G2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 10 family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2619. Eukaryota.
ENOG410ZIMX. LUCA.
GeneTreeiENSGT00680000099679.
HOGENOMiHOG000006538.
HOVERGENiHBG055521.
InParanoidiQ6A1G2.
KOiK11257.
OMAiNAICADY.
OrthoDBiEOG091G064Z.
TreeFamiTF316348.

Family and domain databases

InterProiIPR017176. Alpha-1_3-FUT_met.
IPR031481. Glyco_tran_10_N.
IPR001503. Glyco_trans_10.
[Graphical view]
PANTHERiPTHR11929. PTHR11929. 1 hit.
PfamiPF17039. Glyco_tran_10_N. 1 hit.
PF00852. Glyco_transf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF037332. Alpha1_3FUT_met. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6A1G2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAGCTQLVW GGRLHWGASH LLSCLLALCA LWVLAAAEPT EGGSANVQGV
60 70 80 90 100
GEAALYQGRG QHRVPSEDNV AVLSDQWEPS SFQPSSAFSG TDLGTMVADS
110 120 130 140 150
YRGPGNSDRR SNKELPILLW WSENLFPHFP GDAERIDCPL SSCMVTKNKS
160 170 180 190 200
VKLHKRTKSI IFYGTDFRAY EAPLPRLPHQ TWALFHEESP MNNYVLSHLP
210 220 230 240 250
GIRLFNYTAT FSRESDYPLT LQWLPTIGYL HNPALSMAEK NRWRKNGYAP
260 270 280 290 300
VLYMQSHCDV PSDRDRYVKE LMKHLEIDSY GQCMKNREHP NKRLEDTSTA
310 320 330 340 350
TTEDPEFMAF TARYKFHLAM ENAICADYMT EKLWRPMHLG AIPIYRGSPS
360 370 380 390 400
VRDWMPNNHS IIMIDDFASP KELAEFIMTL DSDDEQYLKY LEYKKPGGTT
410 420 430 440 450
NTFLLSSMEK REWGVNDMTA PNYLNGFECF VCDKENSRIK AEKTYKKSQQ
460 470 480 490 500
GGAAPEPHIA DFNHMGCPMP TPGFGSAQEI PESDSWKQMW LQDYWQSFDQ
510 520 530
GEALTAMIQR NETNQDRFWD YMHETYIKRS MNH
Length:533
Mass (Da):61,023
Last modified:September 13, 2004 - v1
Checksum:iF1A9AD0761345701
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ784816 mRNA. Translation: CAH04945.1.
RefSeqiNP_001002904.1. NM_001002904.2.
UniGeneiStr.57173.

Genome annotation databases

EnsembliENSXETT00000033891; ENSXETP00000033891; ENSXETG00000015541.
GeneIDi444888.
KEGGixtr:444888.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ784816 mRNA. Translation: CAH04945.1.
RefSeqiNP_001002904.1. NM_001002904.2.
UniGeneiStr.57173.

3D structure databases

ProteinModelPortaliQ6A1G2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000033891.

Protein family/group databases

CAZyiGT10. Glycosyltransferase Family 10.

Proteomic databases

PaxDbiQ6A1G2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSXETT00000033891; ENSXETP00000033891; ENSXETG00000015541.
GeneIDi444888.
KEGGixtr:444888.

Organism-specific databases

CTDi170384.
XenbaseiXB-GENE-5933996. fut11.

Phylogenomic databases

eggNOGiKOG2619. Eukaryota.
ENOG410ZIMX. LUCA.
GeneTreeiENSGT00680000099679.
HOGENOMiHOG000006538.
HOVERGENiHBG055521.
InParanoidiQ6A1G2.
KOiK11257.
OMAiNAICADY.
OrthoDBiEOG091G064Z.
TreeFamiTF316348.

Enzyme and pathway databases

UniPathwayiUPA00378.

Gene expression databases

BgeeiENSXETG00000015541.
ExpressionAtlasiQ6A1G2. baseline.

Family and domain databases

InterProiIPR017176. Alpha-1_3-FUT_met.
IPR031481. Glyco_tran_10_N.
IPR001503. Glyco_trans_10.
[Graphical view]
PANTHERiPTHR11929. PTHR11929. 1 hit.
PfamiPF17039. Glyco_tran_10_N. 1 hit.
PF00852. Glyco_transf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF037332. Alpha1_3FUT_met. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiFUT11_XENTR
AccessioniPrimary (citable) accession number: Q6A1G2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: September 13, 2004
Last modified: September 7, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.