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Protein
Submitted name:

MKIAA0109 protein

Gene

Ap2m1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei342Phosphatidylinositol lipid headgroupUniRule annotation1
Binding sitei344Phosphatidylinositol lipid headgroupUniRule annotation1
Binding sitei346Phosphatidylinositol lipid headgroupUniRule annotation1
Binding sitei355Phosphatidylinositol lipid headgroupUniRule annotation1
Binding sitei357Phosphatidylinositol lipid headgroupUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transportSAAS annotation, Transport

Keywords - Ligandi

Lipid-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
MKIAA0109 proteinImported
Gene namesi
Name:Ap2m1Imported
Synonyms:mKIAA0109Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1298405. Ap2m1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ6A0C9.
PeptideAtlasiQ6A0C9.
PRIDEiQ6A0C9.

Expressioni

Gene expression databases

BgeeiENSMUSG00000022841.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000007216.

Structurei

3D structure databases

ProteinModelPortaliQ6A0C9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini171 – 435MHD (mu homology)InterPro annotationAdd BLAST265

Sequence similaritiesi

Belongs to the adaptor complexes medium subunit family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0937. Eukaryota.
ENOG410XPFS. LUCA.
HOGENOMiHOG000173246.
HOVERGENiHBG050516.

Family and domain databases

InterProiIPR022775. AP_mu_sigma_su.
IPR001392. Clathrin_mu.
IPR018240. Clathrin_mu_CS.
IPR011012. Longin-like_dom.
IPR028565. MHD.
[Graphical view]
PfamiPF00928. Adap_comp_sub. 1 hit.
PF01217. Clat_adaptor_s. 1 hit.
[Graphical view]
PIRSFiPIRSF005992. Clathrin_mu. 1 hit.
PRINTSiPR00314. CLATHRINADPT.
SUPFAMiSSF49447. SSF49447. 1 hit.
SSF64356. SSF64356. 1 hit.
PROSITEiPS00990. CLAT_ADAPTOR_M_1. 1 hit.
PS00991. CLAT_ADAPTOR_M_2. 1 hit.
PS51072. MHD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6A0C9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
AATMIGGLFI YNHKGEVLIS RVYRDDIGRN AVDAFRVNVI HARQQVRSPV
60 70 80 90 100
TNIARTSFFH VKRSNIWLAA VTKQNVNAAM VFEFLYKMCD VMAAYFGKIS
110 120 130 140 150
EENIKNNFVL IYELLDEILD FGYPQNSETG ALKTFITQQG IKSQTKEEQS
160 170 180 190 200
QITSQVTGQI GWRREGIKYR RNELFLDVLE SVNLLMSPQG QVLSAHVSGR
210 220 230 240 250
VVMKSYLSGM PECKFGMNDK IVIEKQGKGT ADETSKSGKQ SIAIDDCTFH
260 270 280 290 300
QCVRLSKFDS ERSISFIPPD GEFELMRYRT TKDIILPFRV IPLVREVGRT
310 320 330 340 350
KLEVKVVIKS NFKPSLLAQK IEVRIPTPLN TSGVQVICMK GKAKYKASEN
360 370 380 390 400
AIVWKIKRMA GMKESQISAE IELLPTNDKK KWARPPISMN FEVPFAPSGL
410 420 430
KVRYLKVFEP KLNYSDHDVI KWVRYIGRSG IYETRC
Length:436
Mass (Da):49,633
Last modified:September 13, 2004 - v1
Checksum:i391F4E5B6252D976
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK172889 mRNA. Translation: BAD32167.1.
RefSeqiNP_001289899.1. NM_001302970.1.
UniGeneiMm.18946.

Genome annotation databases

GeneIDi11773.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK172889 mRNA. Translation: BAD32167.1.
RefSeqiNP_001289899.1. NM_001302970.1.
UniGeneiMm.18946.

3D structure databases

ProteinModelPortaliQ6A0C9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000007216.

Proteomic databases

PaxDbiQ6A0C9.
PeptideAtlasiQ6A0C9.
PRIDEiQ6A0C9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi11773.

Organism-specific databases

CTDi1173.
MGIiMGI:1298405. Ap2m1.

Phylogenomic databases

eggNOGiKOG0937. Eukaryota.
ENOG410XPFS. LUCA.
HOGENOMiHOG000173246.
HOVERGENiHBG050516.

Miscellaneous databases

ChiTaRSiAp2m1. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000022841.

Family and domain databases

InterProiIPR022775. AP_mu_sigma_su.
IPR001392. Clathrin_mu.
IPR018240. Clathrin_mu_CS.
IPR011012. Longin-like_dom.
IPR028565. MHD.
[Graphical view]
PfamiPF00928. Adap_comp_sub. 1 hit.
PF01217. Clat_adaptor_s. 1 hit.
[Graphical view]
PIRSFiPIRSF005992. Clathrin_mu. 1 hit.
PRINTSiPR00314. CLATHRINADPT.
SUPFAMiSSF49447. SSF49447. 1 hit.
SSF64356. SSF64356. 1 hit.
PROSITEiPS00990. CLAT_ADAPTOR_M_1. 1 hit.
PS00991. CLAT_ADAPTOR_M_2. 1 hit.
PS51072. MHD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6A0C9_MOUSE
AccessioniPrimary (citable) accession number: Q6A0C9
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2004
Last sequence update: September 13, 2004
Last modified: November 30, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.