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Q69ZX6 (MOR2A_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
MORC family CW-type zinc finger protein 2A
Alternative name(s):
Zinc finger CW-type coiled-coil domain protein 1
Gene names
Name:Morc2a
Synonyms:Kiaa0852, Zcwcc1
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length1030 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 CW-type zinc finger.

Sequence caution

The sequence BAD32320.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 10301029MORC family CW-type zinc finger protein 2A
PRO_0000248243

Regions

Zinc finger490 – 54455CW-type
Coiled coil285 – 36278 Potential
Coiled coil555 – 58329 Potential
Coiled coil738 – 77538 Potential
Coiled coil966 – 101146 Potential
Compositional bias601 – 724124Pro-rich

Amino acid modifications

Modified residue21N-acetylalanine By similarity
Modified residue6141Phosphoserine By similarity
Modified residue7031Phosphoserine By similarity
Modified residue7281Phosphoserine By similarity
Modified residue7311Phosphothreonine By similarity
Modified residue7371Phosphoserine By similarity
Modified residue7411Phosphoserine By similarity
Modified residue7751Phosphoserine By similarity
Modified residue7771Phosphoserine By similarity
Modified residue8541Phosphoserine Ref.4

Sequences

Sequence LengthMass (Da)Tools
Q69ZX6 [UniParc].

Last modified September 5, 2006. Version 2.
Checksum: 0EDD2D09F11C80A2

FASTA1,030117,330
        10         20         30         40         50         60 
MAFTNYSSLN RAQLTFEYLH TNSTTHEFLF GALAELVDNA RDADATRIDI YAERREDLRG 

        70         80         90        100        110        120 
GFMLCFLDDG AGMDPSDAAS VIQFGKSAKR TPESTQIGQY GNGLKSGSMR IGKDFILFTK 

       130        140        150        160        170        180 
KEDTMTCLFL SRTFHEEEGI DEVIVPLPTW NARTREPITD NVEKFAIETE LVYKYSPFHT 

       190        200        210        220        230        240 
EEQVMNQFMK IPGNSGTLVI IFNLKLMDNG EPELDIISNP KDIQMAETSP EGTKPERRSF 

       250        260        270        280        290        300 
RAYAAVLYID PRMRIFIHGH KVQTKRLSCC LYKPRMYKYT SSRFKTRAEQ EVKKAEHVAR 

       310        320        330        340        350        360 
IAEEKAREAE SKARTLEVRM GGDLTRDSRV MLRQVQNTAI TLRREADVKK RIKDAKQRAL 

       370        380        390        400        410        420 
KEPKELNFVF GVNIEHRDLD GMFIYNCSRL IKMYEKVGPQ LEGGMACGGV VGVVDVPYLV 

       430        440        450        460        470        480 
LEPTHNKQDF ADAKEYRHLL RAMGEHLAQY WKDIAIAQRG IIKFWDEFGY LSANWNQPPS 

       490        500        510        520        530        540 
SELRFKRRRA MEIPTTIQCD LCLKWRTLPF QLSSVETDYP DTWVCSMNPD PEQDRCEASE 

       550        560        570        580        590        600 
QKQKVPLGTL KKDPKTQEEK QKQLTEKIRQ QQEKLEALQK TTPIRSQADL KKLPLEVTTR 

       610        620        630        640        650        660 
PIEEPVRRPQ RPRSPPLPAV IKNAPSRPPS IQTPRPSTQL RKTSVISLPK PPTTAARGET 

       670        680        690        700        710        720 
STSRLLQPTE APRKPANPPI KTVPRPTPPV HTPPLSLIPS SKSLREVPAQ KAIKTPVVKK 

       730        740        750        760        770        780 
PEPPVKQSVA TSGRKRSLAV SDEEEAEEEA EKRRERCKRG KLAVKEEKKE ANELSDSAGE 

       790        800        810        820        830        840 
DHPAELRKAQ KDKGLHVEVR VNREWYTGRV TAVEVGKNAV RWKVKFDYVP TDTTPRDRWV 

       850        860        870        880        890        900 
EKGSEDVRLM KPPSPEHQSP DTQQEGGEEE EAMVARQAVA LPEPSTSDGL PIEPDTTATS 

       910        920        930        940        950        960 
PSHETIDLLV QILRNCLRYF LPPSFPISKK ELSVMNSEEL ISFPLKEYFK QYEVGLQNLC 

       970        980        990       1000       1010       1020 
HSYQSRADSR AKASEESLRT SEKKLRETEE KLQKLRTNIV ALLQKVQEDI DINTDDELDA 

      1030 
YIEDLITKGD 

« Hide

References

[1]"Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Seino S., Nishimura M., Kaisho T., Hoshino K., Kitamura H., Nagase T., Ohara O., Koga H.
DNA Res. 11:205-218(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Embryonic intestine.
[2]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J.
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 337-1030.
Strain: C57BL/6.
Tissue: Brain.
[4]"Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.
Mol. Cell. Proteomics 8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-854, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Embryonic fibroblast.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK173042 mRNA. Translation: BAD32320.1. Different initiation.
AL691413 Genomic DNA. Translation: CAI25064.1.
BC063082 mRNA. Translation: AAH63082.1.
CCDSCCDS48741.1.
RefSeqNP_001152760.1. NM_001159288.1.
UniGeneMm.139127.

3D structure databases

ProteinModelPortalQ69ZX6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10090.ENSMUSP00000091087.

PTM databases

PhosphoSiteQ69ZX6.

Proteomic databases

PRIDEQ69ZX6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000093389; ENSMUSP00000091087; ENSMUSG00000034543.
ENSMUST00000096441; ENSMUSP00000094176; ENSMUSG00000034543.
GeneID74522.
KEGGmmu:74522.
UCSCuc007htm.1. mouse.

Organism-specific databases

CTD74522.
MGIMGI:1921772. Morc2a.
RougeSearch...

Phylogenomic databases

eggNOGNOG314457.
GeneTreeENSGT00530000062983.
HOGENOMHOG000060084.
HOVERGENHBG056877.
InParanoidQ69ZX6.
OMARNCLRYF.
OrthoDBEOG71ZP0X.
PhylomeDBQ69ZX6.
TreeFamTF329118.

Gene expression databases

ArrayExpressQ69ZX6.
BgeeQ69ZX6.
CleanExMM_MORC2A.
GenevestigatorQ69ZX6.

Family and domain databases

Gene3D3.30.565.10. 2 hits.
InterProIPR003594. HATPase_ATP-bd.
IPR011124. Znf_CW.
[Graphical view]
PfamPF07496. zf-CW. 1 hit.
[Graphical view]
SMARTSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMSSF55874. SSF55874. 2 hits.
PROSITEPS51050. ZF_CW. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio341012.
PROQ69ZX6.
SOURCESearch...

Entry information

Entry nameMOR2A_MOUSE
AccessionPrimary (citable) accession number: Q69ZX6
Secondary accession number(s): Q5QNQ7, Q6P547
Entry history
Integrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: September 5, 2006
Last modified: July 9, 2014
This is version 76 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot