MORC family CW-type zinc finger protein 2A

Preferred order of sections

Names and origin

Protein names

Recommended name:
MORC family CW-type zinc finger protein 2A

Alternative name(s):
Zinc finger CW-type coiled-coil domain protein 1

Gene names

Name:	Morc2a
Synonyms:	Kiaa0852, Zcwcc1

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	1030 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities	Contains 1 CW-type zinc finger.
Sequence caution	The sequence BAD32320.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Domain	Coiled coil Zinc-finger
Ligand	Metal-binding Zinc
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 1030

1030

MORC family CW-type zinc finger protein 2A

PRO_0000248243

Regions

Zinc finger

490 – 544

55

CW-type

Coiled coil

285 – 362

78

Potential

Coiled coil

555 – 583

29

Potential

Coiled coil

738 – 775

38

Potential

Coiled coil

966 – 1011

46

Potential

Compositional bias

601 – 724

124

Pro-rich

Amino acid modifications

Modified residue

741

1

Phosphoserine Ref.4

Modified residue

854

1

Phosphoserine Ref.5

Sequences

Sequence

Length

Mass (Da)

Tools

Q69ZX6 [UniParc].

Last modified September 5, 2006. Version 2.
Checksum: 0EDD2D09F11C80A2
Show »

FASTA

1,030

117,330

        10         20         30         40         50         60 
MAFTNYSSLN RAQLTFEYLH TNSTTHEFLF GALAELVDNA RDADATRIDI YAERREDLRG 

        70         80         90        100        110        120 
GFMLCFLDDG AGMDPSDAAS VIQFGKSAKR TPESTQIGQY GNGLKSGSMR IGKDFILFTK 

       130        140        150        160        170        180 
KEDTMTCLFL SRTFHEEEGI DEVIVPLPTW NARTREPITD NVEKFAIETE LVYKYSPFHT 

       190        200        210        220        230        240 
EEQVMNQFMK IPGNSGTLVI IFNLKLMDNG EPELDIISNP KDIQMAETSP EGTKPERRSF 

       250        260        270        280        290        300 
RAYAAVLYID PRMRIFIHGH KVQTKRLSCC LYKPRMYKYT SSRFKTRAEQ EVKKAEHVAR 

       310        320        330        340        350        360 
IAEEKAREAE SKARTLEVRM GGDLTRDSRV MLRQVQNTAI TLRREADVKK RIKDAKQRAL 

       370        380        390        400        410        420 
KEPKELNFVF GVNIEHRDLD GMFIYNCSRL IKMYEKVGPQ LEGGMACGGV VGVVDVPYLV 

       430        440        450        460        470        480 
LEPTHNKQDF ADAKEYRHLL RAMGEHLAQY WKDIAIAQRG IIKFWDEFGY LSANWNQPPS 

       490        500        510        520        530        540 
SELRFKRRRA MEIPTTIQCD LCLKWRTLPF QLSSVETDYP DTWVCSMNPD PEQDRCEASE 

       550        560        570        580        590        600 
QKQKVPLGTL KKDPKTQEEK QKQLTEKIRQ QQEKLEALQK TTPIRSQADL KKLPLEVTTR 

       610        620        630        640        650        660 
PIEEPVRRPQ RPRSPPLPAV IKNAPSRPPS IQTPRPSTQL RKTSVISLPK PPTTAARGET 

       670        680        690        700        710        720 
STSRLLQPTE APRKPANPPI KTVPRPTPPV HTPPLSLIPS SKSLREVPAQ KAIKTPVVKK 

       730        740        750        760        770        780 
PEPPVKQSVA TSGRKRSLAV SDEEEAEEEA EKRRERCKRG KLAVKEEKKE ANELSDSAGE 

       790        800        810        820        830        840 
DHPAELRKAQ KDKGLHVEVR VNREWYTGRV TAVEVGKNAV RWKVKFDYVP TDTTPRDRWV 

       850        860        870        880        890        900 
EKGSEDVRLM KPPSPEHQSP DTQQEGGEEE EAMVARQAVA LPEPSTSDGL PIEPDTTATS 

       910        920        930        940        950        960 
PSHETIDLLV QILRNCLRYF LPPSFPISKK ELSVMNSEEL ISFPLKEYFK QYEVGLQNLC 

       970        980        990       1000       1010       1020 
HSYQSRADSR AKASEESLRT SEKKLRETEE KLQKLRTNIV ALLQKVQEDI DINTDDELDA 

      1030 
YIEDLITKGD

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References

[1]	"Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries." Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Seino S., Nishimura M., Kaisho T., Hoshino K., Kitamura H., Nagase T., Ohara O., Koga H. DNA Res. 11:205-218(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Embryonic intestine.
[2]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J.
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 337-1030. Strain: C57BL/6. Tissue: Brain.
[4]	"Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry." Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J., Faessler R., Mann M. J. Proteome Res. 7:5314-5326(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-741, MASS SPECTROMETRY. Tissue: Melanoma.
[5]	"Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry." Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J. Mol. Cell. Proteomics 8:904-912(2009) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-854, MASS SPECTROMETRY. Tissue: Embryonic fibroblast.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK173042 mRNA. Translation: BAD32320.1. Different initiation. AL691413 Genomic DNA. Translation: CAI25064.1. BC063082 mRNA. Translation: AAH63082.1.
IPI	IPI00623382.
RefSeq	NP_001152760.1. NM_001159288.1.
UniGene	Mm.139127.
3D structure databases
ProteinModelPortal	Q69ZX6.
SMR	Q69ZX6. Positions 27-124, 492-542.
ModBase	Search...
Protein-protein interaction databases
STRING	10090.ENSMUSP00000091087.
PTM databases
PhosphoSite	Q69ZX6.
Proteomic databases
PRIDE	Q69ZX6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000093389; ENSMUSP00000091087; ENSMUSG00000034543. ENSMUST00000096441; ENSMUSP00000094176; ENSMUSG00000034543.
GeneID	74522.
KEGG	mmu:74522.
UCSC	uc007htm.1. mouse.
Organism-specific databases
CTD	74522.
MGI	MGI:1921772. Morc2a.
Rouge	Search...
Phylogenomic databases
eggNOG	NOG314457.
GeneTree	ENSGT00530000062983.
HOGENOM	HOG000060084.
HOVERGEN	HBG056877.
InParanoid	Q69ZX6.
OMA	RNCLRYF.
OrthoDB	EOG473PQP.
Gene expression databases
ArrayExpress	Q69ZX6.
Bgee	Q69ZX6.
CleanEx	MM_MORC2A.
Genevestigator	Q69ZX6.
GermOnline	ENSMUSG00000034543. Mus musculus.
Family and domain databases
Gene3D	3.30.565.10. 2 hits.
InterPro	IPR003594. HATPase_ATP-bd. IPR011124. Znf_CW. [Graphical view]
Pfam	PF07496. zf-CW. 1 hit. [Graphical view]
SMART	SM00387. HATPase_c. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit.
PROSITE	PS51050. ZF_CW. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	341012.
SOURCE	Search...

Entry information

Entry name

MOR2A_MOUSE

Accession

Primary (citable) accession number: Q69ZX6
Secondary accession number(s): Q5QNQ7, Q6P547

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 5, 2006
Last sequence update:	September 5, 2006
Last modified:	May 1, 2013
This is version 67 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Amino acid modifications

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Other

Entry information

Relevant documents