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Q69ZX6

- MOR2A_MOUSE

UniProt

Q69ZX6 - MOR2A_MOUSE

Protein

MORC family CW-type zinc finger protein 2A

Gene

Morc2a

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 2 (05 Sep 2006)
      Previous versions | rss
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    Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri490 – 54455CW-typePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. zinc ion binding Source: InterPro

    Keywords - Ligandi

    Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    MORC family CW-type zinc finger protein 2A
    Alternative name(s):
    Zinc finger CW-type coiled-coil domain protein 1
    Gene namesi
    Name:Morc2aImported
    Synonyms:Kiaa0852Imported, Zcwcc1Imported
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 11

    Organism-specific databases

    MGIiMGI:1921772. Morc2a.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedBy similarity
    Chaini2 – 10301029MORC family CW-type zinc finger protein 2APRO_0000248243Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylalanineBy similarity
    Modified residuei614 – 6141PhosphoserineBy similarity
    Modified residuei703 – 7031PhosphoserineBy similarity
    Modified residuei728 – 7281PhosphoserineBy similarity
    Modified residuei731 – 7311PhosphothreonineBy similarity
    Modified residuei737 – 7371PhosphoserineBy similarity
    Modified residuei741 – 7411PhosphoserineBy similarity
    Modified residuei775 – 7751PhosphoserineBy similarity
    Modified residuei777 – 7771PhosphoserineBy similarity
    Modified residuei854 – 8541Phosphoserine1 Publication

    Keywords - PTMi

    Acetylation, Phosphoprotein

    Proteomic databases

    PRIDEiQ69ZX6.

    PTM databases

    PhosphoSiteiQ69ZX6.

    Expressioni

    Gene expression databases

    ArrayExpressiQ69ZX6.
    BgeeiQ69ZX6.
    CleanExiMM_MORC2A.
    GenevestigatoriQ69ZX6.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000091087.

    Structurei

    3D structure databases

    ProteinModelPortaliQ69ZX6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili285 – 36278Sequence AnalysisAdd
    BLAST
    Coiled coili555 – 58329Sequence AnalysisAdd
    BLAST
    Coiled coili738 – 77538Sequence AnalysisAdd
    BLAST
    Coiled coili966 – 101146Sequence AnalysisAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi601 – 724124Pro-richSequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Contains 1 CW-type zinc finger.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri490 – 54455CW-typePROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Coiled coil, Zinc-finger

    Phylogenomic databases

    eggNOGiNOG314457.
    GeneTreeiENSGT00530000062983.
    HOGENOMiHOG000060084.
    HOVERGENiHBG056877.
    InParanoidiQ69ZX6.
    OMAiRNCLRYF.
    OrthoDBiEOG71ZP0X.
    PhylomeDBiQ69ZX6.
    TreeFamiTF329118.

    Family and domain databases

    Gene3Di3.30.565.10. 2 hits.
    InterProiIPR003594. HATPase_ATP-bd.
    IPR011124. Znf_CW.
    [Graphical view]
    PfamiPF07496. zf-CW. 1 hit.
    [Graphical view]
    SMARTiSM00387. HATPase_c. 1 hit.
    [Graphical view]
    SUPFAMiSSF55874. SSF55874. 2 hits.
    PROSITEiPS51050. ZF_CW. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q69ZX6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAFTNYSSLN RAQLTFEYLH TNSTTHEFLF GALAELVDNA RDADATRIDI     50
    YAERREDLRG GFMLCFLDDG AGMDPSDAAS VIQFGKSAKR TPESTQIGQY 100
    GNGLKSGSMR IGKDFILFTK KEDTMTCLFL SRTFHEEEGI DEVIVPLPTW 150
    NARTREPITD NVEKFAIETE LVYKYSPFHT EEQVMNQFMK IPGNSGTLVI 200
    IFNLKLMDNG EPELDIISNP KDIQMAETSP EGTKPERRSF RAYAAVLYID 250
    PRMRIFIHGH KVQTKRLSCC LYKPRMYKYT SSRFKTRAEQ EVKKAEHVAR 300
    IAEEKAREAE SKARTLEVRM GGDLTRDSRV MLRQVQNTAI TLRREADVKK 350
    RIKDAKQRAL KEPKELNFVF GVNIEHRDLD GMFIYNCSRL IKMYEKVGPQ 400
    LEGGMACGGV VGVVDVPYLV LEPTHNKQDF ADAKEYRHLL RAMGEHLAQY 450
    WKDIAIAQRG IIKFWDEFGY LSANWNQPPS SELRFKRRRA MEIPTTIQCD 500
    LCLKWRTLPF QLSSVETDYP DTWVCSMNPD PEQDRCEASE QKQKVPLGTL 550
    KKDPKTQEEK QKQLTEKIRQ QQEKLEALQK TTPIRSQADL KKLPLEVTTR 600
    PIEEPVRRPQ RPRSPPLPAV IKNAPSRPPS IQTPRPSTQL RKTSVISLPK 650
    PPTTAARGET STSRLLQPTE APRKPANPPI KTVPRPTPPV HTPPLSLIPS 700
    SKSLREVPAQ KAIKTPVVKK PEPPVKQSVA TSGRKRSLAV SDEEEAEEEA 750
    EKRRERCKRG KLAVKEEKKE ANELSDSAGE DHPAELRKAQ KDKGLHVEVR 800
    VNREWYTGRV TAVEVGKNAV RWKVKFDYVP TDTTPRDRWV EKGSEDVRLM 850
    KPPSPEHQSP DTQQEGGEEE EAMVARQAVA LPEPSTSDGL PIEPDTTATS 900
    PSHETIDLLV QILRNCLRYF LPPSFPISKK ELSVMNSEEL ISFPLKEYFK 950
    QYEVGLQNLC HSYQSRADSR AKASEESLRT SEKKLRETEE KLQKLRTNIV 1000
    ALLQKVQEDI DINTDDELDA YIEDLITKGD 1030
    Length:1,030
    Mass (Da):117,330
    Last modified:September 5, 2006 - v2
    Checksum:i0EDD2D09F11C80A2
    GO

    Sequence cautioni

    The sequence BAD32320.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK173042 mRNA. Translation: BAD32320.1. Different initiation.
    AL691413 Genomic DNA. Translation: CAI25064.1.
    BC063082 mRNA. Translation: AAH63082.1.
    CCDSiCCDS48741.1.
    RefSeqiNP_001152760.1. NM_001159288.1.
    UniGeneiMm.139127.

    Genome annotation databases

    EnsembliENSMUST00000093389; ENSMUSP00000091087; ENSMUSG00000034543.
    ENSMUST00000096441; ENSMUSP00000094176; ENSMUSG00000034543.
    GeneIDi74522.
    KEGGimmu:74522.
    UCSCiuc007htm.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK173042 mRNA. Translation: BAD32320.1 . Different initiation.
    AL691413 Genomic DNA. Translation: CAI25064.1 .
    BC063082 mRNA. Translation: AAH63082.1 .
    CCDSi CCDS48741.1.
    RefSeqi NP_001152760.1. NM_001159288.1.
    UniGenei Mm.139127.

    3D structure databases

    ProteinModelPortali Q69ZX6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000091087.

    PTM databases

    PhosphoSitei Q69ZX6.

    Proteomic databases

    PRIDEi Q69ZX6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000093389 ; ENSMUSP00000091087 ; ENSMUSG00000034543 .
    ENSMUST00000096441 ; ENSMUSP00000094176 ; ENSMUSG00000034543 .
    GeneIDi 74522.
    KEGGi mmu:74522.
    UCSCi uc007htm.1. mouse.

    Organism-specific databases

    CTDi 74522.
    MGIi MGI:1921772. Morc2a.
    Rougei Search...

    Phylogenomic databases

    eggNOGi NOG314457.
    GeneTreei ENSGT00530000062983.
    HOGENOMi HOG000060084.
    HOVERGENi HBG056877.
    InParanoidi Q69ZX6.
    OMAi RNCLRYF.
    OrthoDBi EOG71ZP0X.
    PhylomeDBi Q69ZX6.
    TreeFami TF329118.

    Miscellaneous databases

    NextBioi 341012.
    PROi Q69ZX6.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q69ZX6.
    Bgeei Q69ZX6.
    CleanExi MM_MORC2A.
    Genevestigatori Q69ZX6.

    Family and domain databases

    Gene3Di 3.30.565.10. 2 hits.
    InterProi IPR003594. HATPase_ATP-bd.
    IPR011124. Znf_CW.
    [Graphical view ]
    Pfami PF07496. zf-CW. 1 hit.
    [Graphical view ]
    SMARTi SM00387. HATPase_c. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55874. SSF55874. 2 hits.
    PROSITEi PS51050. ZF_CW. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Seino S., Nishimura M., Kaisho T., Hoshino K., Kitamura H., Nagase T., Ohara O., Koga H.
      DNA Res. 11:205-218(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Embryonic intestineImported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6J.
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 337-1030.
      Strain: C57BL/6Imported.
      Tissue: BrainImported.
    4. "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
      Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.
      Mol. Cell. Proteomics 8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-854, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Embryonic fibroblast.

    Entry informationi

    Entry nameiMOR2A_MOUSE
    AccessioniPrimary (citable) accession number: Q69ZX6
    Secondary accession number(s): Q5QNQ7, Q6P547
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 5, 2006
    Last sequence update: September 5, 2006
    Last modified: October 1, 2014
    This is version 77 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3