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Q69ZX6

- MOR2A_MOUSE

UniProt

Q69ZX6 - MOR2A_MOUSE

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Protein

MORC family CW-type zinc finger protein 2A

Gene
Morc2a, Kiaa0852, Zcwcc1
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri490 – 54455CW-typeAdd
BLAST

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
MORC family CW-type zinc finger protein 2A
Alternative name(s):
Zinc finger CW-type coiled-coil domain protein 1
Gene namesi
Name:Morc2a
Synonyms:Kiaa0852, Zcwcc1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 11

Organism-specific databases

MGIiMGI:1921772. Morc2a.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed By similarity
Chaini2 – 10301029MORC family CW-type zinc finger protein 2APRO_0000248243Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanine By similarity
Modified residuei614 – 6141Phosphoserine By similarity
Modified residuei703 – 7031Phosphoserine By similarity
Modified residuei728 – 7281Phosphoserine By similarity
Modified residuei731 – 7311Phosphothreonine By similarity
Modified residuei737 – 7371Phosphoserine By similarity
Modified residuei741 – 7411Phosphoserine By similarity
Modified residuei775 – 7751Phosphoserine By similarity
Modified residuei777 – 7771Phosphoserine By similarity
Modified residuei854 – 8541Phosphoserine1 Publication

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PRIDEiQ69ZX6.

PTM databases

PhosphoSiteiQ69ZX6.

Expressioni

Gene expression databases

ArrayExpressiQ69ZX6.
BgeeiQ69ZX6.
CleanExiMM_MORC2A.
GenevestigatoriQ69ZX6.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000091087.

Structurei

3D structure databases

ProteinModelPortaliQ69ZX6.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili285 – 36278 Reviewed predictionAdd
BLAST
Coiled coili555 – 58329 Reviewed predictionAdd
BLAST
Coiled coili738 – 77538 Reviewed predictionAdd
BLAST
Coiled coili966 – 101146 Reviewed predictionAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi601 – 724124Pro-richAdd
BLAST

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri490 – 54455CW-typeAdd
BLAST

Keywords - Domaini

Coiled coil, Zinc-finger

Phylogenomic databases

eggNOGiNOG314457.
GeneTreeiENSGT00530000062983.
HOGENOMiHOG000060084.
HOVERGENiHBG056877.
InParanoidiQ69ZX6.
OMAiRNCLRYF.
OrthoDBiEOG71ZP0X.
PhylomeDBiQ69ZX6.
TreeFamiTF329118.

Family and domain databases

Gene3Di3.30.565.10. 2 hits.
InterProiIPR003594. HATPase_ATP-bd.
IPR011124. Znf_CW.
[Graphical view]
PfamiPF07496. zf-CW. 1 hit.
[Graphical view]
SMARTiSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMiSSF55874. SSF55874. 2 hits.
PROSITEiPS51050. ZF_CW. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q69ZX6-1 [UniParc]FASTAAdd to Basket

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MAFTNYSSLN RAQLTFEYLH TNSTTHEFLF GALAELVDNA RDADATRIDI     50
YAERREDLRG GFMLCFLDDG AGMDPSDAAS VIQFGKSAKR TPESTQIGQY 100
GNGLKSGSMR IGKDFILFTK KEDTMTCLFL SRTFHEEEGI DEVIVPLPTW 150
NARTREPITD NVEKFAIETE LVYKYSPFHT EEQVMNQFMK IPGNSGTLVI 200
IFNLKLMDNG EPELDIISNP KDIQMAETSP EGTKPERRSF RAYAAVLYID 250
PRMRIFIHGH KVQTKRLSCC LYKPRMYKYT SSRFKTRAEQ EVKKAEHVAR 300
IAEEKAREAE SKARTLEVRM GGDLTRDSRV MLRQVQNTAI TLRREADVKK 350
RIKDAKQRAL KEPKELNFVF GVNIEHRDLD GMFIYNCSRL IKMYEKVGPQ 400
LEGGMACGGV VGVVDVPYLV LEPTHNKQDF ADAKEYRHLL RAMGEHLAQY 450
WKDIAIAQRG IIKFWDEFGY LSANWNQPPS SELRFKRRRA MEIPTTIQCD 500
LCLKWRTLPF QLSSVETDYP DTWVCSMNPD PEQDRCEASE QKQKVPLGTL 550
KKDPKTQEEK QKQLTEKIRQ QQEKLEALQK TTPIRSQADL KKLPLEVTTR 600
PIEEPVRRPQ RPRSPPLPAV IKNAPSRPPS IQTPRPSTQL RKTSVISLPK 650
PPTTAARGET STSRLLQPTE APRKPANPPI KTVPRPTPPV HTPPLSLIPS 700
SKSLREVPAQ KAIKTPVVKK PEPPVKQSVA TSGRKRSLAV SDEEEAEEEA 750
EKRRERCKRG KLAVKEEKKE ANELSDSAGE DHPAELRKAQ KDKGLHVEVR 800
VNREWYTGRV TAVEVGKNAV RWKVKFDYVP TDTTPRDRWV EKGSEDVRLM 850
KPPSPEHQSP DTQQEGGEEE EAMVARQAVA LPEPSTSDGL PIEPDTTATS 900
PSHETIDLLV QILRNCLRYF LPPSFPISKK ELSVMNSEEL ISFPLKEYFK 950
QYEVGLQNLC HSYQSRADSR AKASEESLRT SEKKLRETEE KLQKLRTNIV 1000
ALLQKVQEDI DINTDDELDA YIEDLITKGD 1030
Length:1,030
Mass (Da):117,330
Last modified:September 5, 2006 - v2
Checksum:i0EDD2D09F11C80A2
GO

Sequence cautioni

The sequence BAD32320.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK173042 mRNA. Translation: BAD32320.1. Different initiation.
AL691413 Genomic DNA. Translation: CAI25064.1.
BC063082 mRNA. Translation: AAH63082.1.
CCDSiCCDS48741.1.
RefSeqiNP_001152760.1. NM_001159288.1.
UniGeneiMm.139127.

Genome annotation databases

EnsembliENSMUST00000093389; ENSMUSP00000091087; ENSMUSG00000034543.
ENSMUST00000096441; ENSMUSP00000094176; ENSMUSG00000034543.
GeneIDi74522.
KEGGimmu:74522.
UCSCiuc007htm.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK173042 mRNA. Translation: BAD32320.1 . Different initiation.
AL691413 Genomic DNA. Translation: CAI25064.1 .
BC063082 mRNA. Translation: AAH63082.1 .
CCDSi CCDS48741.1.
RefSeqi NP_001152760.1. NM_001159288.1.
UniGenei Mm.139127.

3D structure databases

ProteinModelPortali Q69ZX6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000091087.

PTM databases

PhosphoSitei Q69ZX6.

Proteomic databases

PRIDEi Q69ZX6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000093389 ; ENSMUSP00000091087 ; ENSMUSG00000034543 .
ENSMUST00000096441 ; ENSMUSP00000094176 ; ENSMUSG00000034543 .
GeneIDi 74522.
KEGGi mmu:74522.
UCSCi uc007htm.1. mouse.

Organism-specific databases

CTDi 74522.
MGIi MGI:1921772. Morc2a.
Rougei Search...

Phylogenomic databases

eggNOGi NOG314457.
GeneTreei ENSGT00530000062983.
HOGENOMi HOG000060084.
HOVERGENi HBG056877.
InParanoidi Q69ZX6.
OMAi RNCLRYF.
OrthoDBi EOG71ZP0X.
PhylomeDBi Q69ZX6.
TreeFami TF329118.

Miscellaneous databases

NextBioi 341012.
PROi Q69ZX6.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q69ZX6.
Bgeei Q69ZX6.
CleanExi MM_MORC2A.
Genevestigatori Q69ZX6.

Family and domain databases

Gene3Di 3.30.565.10. 2 hits.
InterProi IPR003594. HATPase_ATP-bd.
IPR011124. Znf_CW.
[Graphical view ]
Pfami PF07496. zf-CW. 1 hit.
[Graphical view ]
SMARTi SM00387. HATPase_c. 1 hit.
[Graphical view ]
SUPFAMi SSF55874. SSF55874. 2 hits.
PROSITEi PS51050. ZF_CW. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
    Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Seino S., Nishimura M., Kaisho T., Hoshino K., Kitamura H., Nagase T., Ohara O., Koga H.
    DNA Res. 11:205-218(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Embryonic intestine.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 337-1030.
    Strain: C57BL/6.
    Tissue: Brain.
  4. "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
    Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.
    Mol. Cell. Proteomics 8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-854, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic fibroblast.

Entry informationi

Entry nameiMOR2A_MOUSE
AccessioniPrimary (citable) accession number: Q69ZX6
Secondary accession number(s): Q5QNQ7, Q6P547
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: September 5, 2006
Last modified: July 9, 2014
This is version 76 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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