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Protein
Submitted name:

MKIAA1144 protein

Gene

Kcns2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel, Potassium channelSAAS annotation, Voltage-gated channelSAAS annotation
Biological processIon transport, Potassium transport, Transport
LigandPotassium

Names & Taxonomyi

Protein namesi
Submitted name:
MKIAA1144 proteinImported
Gene namesi
Name:Kcns2Imported
Synonyms:mKIAA1144Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1197011 Kcns2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei223 – 244HelicalSequence analysisAdd BLAST22
Transmembranei295 – 316HelicalSequence analysisAdd BLAST22
Transmembranei367 – 385HelicalSequence analysisAdd BLAST19
Transmembranei392 – 412HelicalSequence analysisAdd BLAST21
Transmembranei424 – 445HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

GenevisibleiQ69ZQ8 MM

Structurei

3D structure databases

ProteinModelPortaliQ69ZQ8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini52 – 161BTBInterPro annotationAdd BLAST110

Sequence similaritiesi

Belongs to the potassium channel family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3713 Eukaryota
COG1226 LUCA
HOGENOMiHOG000231016
HOVERGENiHBG052230

Family and domain databases

Gene3Di1.20.120.3501 hit
InterProiView protein in InterPro
IPR000210 BTB/POZ_dom
IPR005821 Ion_trans_dom
IPR003968 K_chnl_volt-dep_Kv
IPR003971 K_chnl_volt-dep_Kv9
IPR011333 SKP1/BTB/POZ_sf
IPR003131 T1-type_BTB
IPR028325 VG_K_chnl
IPR027359 Volt_channel_dom_sf
PANTHERiPTHR11537 PTHR11537, 1 hit
PfamiView protein in Pfam
PF02214 BTB_2, 1 hit
PF00520 Ion_trans, 1 hit
PRINTSiPR00169 KCHANNEL
PR01494 KV9CHANNEL
PR01491 KVCHANNEL
SMARTiView protein in SMART
SM00225 BTB, 1 hit
SUPFAMiSSF54695 SSF54695, 1 hit

Sequencei

Sequence statusi: Fragment.

Q69ZQ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
CLPAGRGSFP PASAAGSRAP RCSAPARRGR LGISSMTRQS LWDVSDTDVE
60 70 80 90 100
DGEIRINVGG FKRRLRSHTL LRFPETRLGR LLLCHSREAI LELCDDYDDV
110 120 130 140 150
QREFYFDRNP ELFPYVLHFY HTGKLHVMAE LCVFSFSQEI EYWGINEFFI
160 170 180 190 200
DSCCSYSYHG RKVEPEQEKW DEQSDQESTT SSFDEILAFY NDASKFDGQP
210 220 230 240 250
LGNFRRQLWL ALDNPGYSVL SRVFSVLSIL VVLGSIITMC LNSLPDFQIP
260 270 280 290 300
DSQGNPGEDP RFEIVEHFGI AWFTFELVAR FAVAPDFLKF FKNALNLIDL
310 320 330 340 350
MSIVPFYITL VVNLVVESSP TLANLGRVAQ VLRLMRIFRI LKLARHSTGL
360 370 380 390 400
RSLGATLKYS YKEVGLLLLY LSVGISIFSV VAYTIEKEEN EGLATIPACW
410 420 430 440 450
WWATVSMTTV GYGDVVPGTT AGKLTASACI LAGILVVVLP ITLIFNKFSH
460 470 480 490 500
FYRRQKQLES AMRSCDFGDG MKEVPSVNLR DYYAHKVKSL MASLTNMSRS
510
SPSELSLDDS LH
Length:512
Mass (Da):57,710
Last modified:September 13, 2004 - v1
Checksum:i34B5298F4B02D0C8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK173110 mRNA Translation: BAD32388.1
RefSeqiNP_851834.1, NM_181317.4
UniGeneiMm.487585
Mm.71045

Genome annotation databases

GeneIDi16539

Similar proteinsi

Entry informationi

Entry nameiQ69ZQ8_MOUSE
AccessioniPrimary (citable) accession number: Q69ZQ8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2004
Last sequence update: September 13, 2004
Last modified: February 28, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)