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Protein
Submitted name:

MKIAA1144 protein

Gene

Kcns2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. delayed rectifier potassium channel activity Source: GO_Central

GO - Biological processi

  1. potassium ion transmembrane transport Source: GO_Central
  2. protein homooligomerization Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Potassium channelSAAS annotation, Voltage-gated channelSAAS annotation

Keywords - Biological processi

Ion transport, Potassium transport, Transport

Keywords - Ligandi

Potassium

Names & Taxonomyi

Protein namesi
Submitted name:
MKIAA1144 proteinImported
Gene namesi
Name:Kcns2Imported
Synonyms:mKIAA1144Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1197011. Kcns2.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: GO_Central
  2. voltage-gated potassium channel complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiQ69ZQ8.

Expressioni

Gene expression databases

BgeeiQ69ZQ8.
ExpressionAtlasiQ69ZQ8. baseline and differential.
GenevestigatoriQ69ZQ8.

Structurei

3D structure databases

ProteinModelPortaliQ69ZQ8.
SMRiQ69ZQ8. Positions 48-455.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

HOGENOMiHOG000231016.
HOVERGENiHBG052230.
KOiK04932.

Family and domain databases

Gene3Di1.20.120.350. 1 hit.
InterProiIPR000210. BTB/POZ-like.
IPR011333. BTB/POZ_fold.
IPR027359. Channel_four-helix_dom.
IPR005821. Ion_trans_dom.
IPR003091. K_chnl.
IPR003968. K_chnl_volt-dep_Kv.
IPR003971. K_chnl_volt-dep_Kv9.
IPR003131. T1-type_BTB.
IPR028325. VG_K_chnl.
[Graphical view]
PANTHERiPTHR11537. PTHR11537. 1 hit.
PfamiPF02214. BTB_2. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR00169. KCHANNEL.
PR01494. KV9CHANNEL.
PR01491. KVCHANNEL.
SMARTiSM00225. BTB. 1 hit.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q69ZQ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
CLPAGRGSFP PASAAGSRAP RCSAPARRGR LGISSMTRQS LWDVSDTDVE
60 70 80 90 100
DGEIRINVGG FKRRLRSHTL LRFPETRLGR LLLCHSREAI LELCDDYDDV
110 120 130 140 150
QREFYFDRNP ELFPYVLHFY HTGKLHVMAE LCVFSFSQEI EYWGINEFFI
160 170 180 190 200
DSCCSYSYHG RKVEPEQEKW DEQSDQESTT SSFDEILAFY NDASKFDGQP
210 220 230 240 250
LGNFRRQLWL ALDNPGYSVL SRVFSVLSIL VVLGSIITMC LNSLPDFQIP
260 270 280 290 300
DSQGNPGEDP RFEIVEHFGI AWFTFELVAR FAVAPDFLKF FKNALNLIDL
310 320 330 340 350
MSIVPFYITL VVNLVVESSP TLANLGRVAQ VLRLMRIFRI LKLARHSTGL
360 370 380 390 400
RSLGATLKYS YKEVGLLLLY LSVGISIFSV VAYTIEKEEN EGLATIPACW
410 420 430 440 450
WWATVSMTTV GYGDVVPGTT AGKLTASACI LAGILVVVLP ITLIFNKFSH
460 470 480 490 500
FYRRQKQLES AMRSCDFGDG MKEVPSVNLR DYYAHKVKSL MASLTNMSRS
510
SPSELSLDDS LH
Length:512
Mass (Da):57,710
Last modified:September 13, 2004 - v1
Checksum:i34B5298F4B02D0C8
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK173110 mRNA. Translation: BAD32388.1.
RefSeqiNP_851834.1. NM_181317.4.
UniGeneiMm.487585.
Mm.71045.

Genome annotation databases

GeneIDi16539.
KEGGimmu:16539.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK173110 mRNA. Translation: BAD32388.1.
RefSeqiNP_851834.1. NM_181317.4.
UniGeneiMm.487585.
Mm.71045.

3D structure databases

ProteinModelPortaliQ69ZQ8.
SMRiQ69ZQ8. Positions 48-455.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ69ZQ8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi16539.
KEGGimmu:16539.

Organism-specific databases

CTDi3788.
MGIiMGI:1197011. Kcns2.

Phylogenomic databases

HOGENOMiHOG000231016.
HOVERGENiHBG052230.
KOiK04932.

Miscellaneous databases

ChiTaRSiKcns2. mouse.
NextBioi289995.
SOURCEiSearch...

Gene expression databases

BgeeiQ69ZQ8.
ExpressionAtlasiQ69ZQ8. baseline and differential.
GenevestigatoriQ69ZQ8.

Family and domain databases

Gene3Di1.20.120.350. 1 hit.
InterProiIPR000210. BTB/POZ-like.
IPR011333. BTB/POZ_fold.
IPR027359. Channel_four-helix_dom.
IPR005821. Ion_trans_dom.
IPR003091. K_chnl.
IPR003968. K_chnl_volt-dep_Kv.
IPR003971. K_chnl_volt-dep_Kv9.
IPR003131. T1-type_BTB.
IPR028325. VG_K_chnl.
[Graphical view]
PANTHERiPTHR11537. PTHR11537. 1 hit.
PfamiPF02214. BTB_2. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR00169. KCHANNEL.
PR01494. KV9CHANNEL.
PR01491. KVCHANNEL.
SMARTiSM00225. BTB. 1 hit.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
    Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Seino S., Nishimura M., Kaisho T., Hoshino K., Kitamura H., Nagase T., Ohara O., Koga H.
    DNA Res. 11:205-218(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Fetal brainImported.

Entry informationi

Entry nameiQ69ZQ8_MOUSE
AccessioniPrimary (citable) accession number: Q69ZQ8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2004
Last sequence update: September 13, 2004
Last modified: March 4, 2015
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.