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Protein

Probable JmjC domain-containing histone demethylation protein 2C

Gene

Jmjd1c

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity).By similarity

Cofactori

Fe2+By similarityNote: Binds 1 Fe2+ ion per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi2146 – 21461Iron; catalyticPROSITE-ProRule annotation
Metal bindingi2148 – 21481Iron; catalyticPROSITE-ProRule annotation
Metal bindingi2276 – 22761Iron; catalyticPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri1657 – 168226C6-typeSequence analysisAdd
BLAST

GO - Molecular functioni

GO - Biological processi

  • chromatin modification Source: UniProtKB-KW
  • epithelial cell morphogenesis Source: MGI
  • maintenance of cell number Source: MGI
  • male germ-line stem cell population maintenance Source: MGI
  • male gonad development Source: MGI
  • regulation of transcription, DNA-templated Source: UniProtKB-KW
  • reproductive senescence Source: MGI
  • seminiferous tubule development Source: MGI
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulator, Dioxygenase, Oxidoreductase

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

Iron, Metal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-MMU-983231. Factors involved in megakaryocyte development and platelet production.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable JmjC domain-containing histone demethylation protein 2C (EC:1.14.11.-)
Alternative name(s):
Jumonji domain-containing protein 1C
Gene namesi
Name:Jmjd1c
Synonyms:Jhdm2c, Kiaa1380
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1918614. Jmjd1c.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 23502350Probable JmjC domain-containing histone demethylation protein 2CPRO_0000234375Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei135 – 1351PhosphoserineCombined sources
Modified residuei138 – 1381PhosphoserineCombined sources
Modified residuei191 – 1911PhosphoserineBy similarity
Modified residuei194 – 1941PhosphoserineBy similarity
Modified residuei294 – 2941PhosphoserineCombined sources
Modified residuei436 – 4361PhosphoserineBy similarity
Modified residuei457 – 4571PhosphoserineBy similarity
Modified residuei460 – 4601PhosphoserineBy similarity
Modified residuei471 – 4711PhosphoserineCombined sources
Modified residuei1800 – 18001PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ69ZK6.
MaxQBiQ69ZK6.
PaxDbiQ69ZK6.
PRIDEiQ69ZK6.

PTM databases

iPTMnetiQ69ZK6.
PhosphoSiteiQ69ZK6.

Expressioni

Gene expression databases

BgeeiQ69ZK6.
CleanExiMM_JMJD1C.
ExpressionAtlasiQ69ZK6. baseline and differential.
GenevisibleiQ69ZK6. MM.

Interactioni

Protein-protein interaction databases

BioGridi224438. 3 interactions.
IntActiQ69ZK6. 1 interaction.
STRINGi10090.ENSMUSP00000056227.

Structurei

3D structure databases

ProteinModelPortaliQ69ZK6.
SMRiQ69ZK6. Positions 1967-2307.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2084 – 2308225JmjCPROSITE-ProRule annotationAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi1876 – 18805LXXLL motif

Domaini

Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.By similarity

Sequence similaritiesi

Belongs to the JHDM2 histone demethylase family.Curated
Contains 1 JmjC domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri1657 – 168226C6-typeSequence analysisAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG1356. Eukaryota.
ENOG410XTAA. LUCA.
GeneTreeiENSGT00530000063039.
HOGENOMiHOG000113130.
HOVERGENiHBG079631.
InParanoidiQ69ZK6.
KOiK11449.
TreeFamiTF324723.

Family and domain databases

InterProiIPR003347. JmjC_dom.
[Graphical view]
PfamiPF02373. JmjC. 1 hit.
[Graphical view]
SMARTiSM00558. JmjC. 1 hit.
[Graphical view]
PROSITEiPS51184. JMJC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q69ZK6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQGPYSLNGY RVRVYRQDSA TQWFTGIITH HDLFTRTMIV MNDQVLEPQN
60 70 80 90 100
VDPSMVQMTF LDDVVHSLLK GENIGITSRR RSRASQNIST VHGHYTRAQA
110 120 130 140 150
NSPRPAMNSQ AAVPKQNTHQ QQQQRSIRPN KRKGSDSSIP DEEKMKEDKY
160 170 180 190 200
DCVSRGENPK GKNKHVVTKR RKPEEAEKRL SMKRLRTDNA SDASESSDAE
210 220 230 240 250
SSSKRVTETS SSEPMPEYEP KNKVTSKVNG EEGQSQAAEE AGEETLIDTR
260 270 280 290 300
PPWDQMQEDK NHNEGEKPKS TDSHLQDKMT LRSSEQATVA DHNSNDSVLQ
310 320 330 340 350
ECNVENQRTV ELLPKDRLVS RTPTPKCVTD IKNDTHSERA AQENLNTFGL
360 370 380 390 400
QTPENMDPNV SDSKHSNAKY LETAKQDCDQ SWVSDVVKVD LTQSSVTNAP
410 420 430 440 450
SGSDKRDTEK ERNHYVSYMS SLSAVSVTED QLHKRSPPPE TIKAKLTTSV
460 470 480 490 500
DTQKAKSSSS PEVVKPKITH SPDSVKSKAA YGNSQAVGER RLANKIEHEL
510 520 530 540 550
SRGSFHPVPT RGSALETTKS PLIIDKNEHF TVYRDPALIG SETGANHISP
560 570 580 590 600
FLSQHPFSLH SSSHRTCLNP GTHHPALTPG PHLLAGSTSQ TPLPTINTHP
610 620 630 640 650
LTSGPHHPVH HPHLLPTVLP GVPTASLLGG HPRLESAHAS SLSHLALAHQ
660 670 680 690 700
QQQQLLQHQS PHLLGQAHPS ASYNQLGLYP IIWQYPNGTH AYSGLGLPSS
710 720 730 740 750
KWVHPENAVN AEASLRRNSP SPWLHQPTPV TSADGIGLLS HIPVRPSSAE
760 770 780 790 800
PHRPHKITVH SSPPLTKTLA DHHKEELERK AFMEPLRSNA STSVKGDLDL
810 820 830 840 850
NRSQAGKDCH LHRHFVGPRP PQETGERLNK YKEEHRRILQ ESIDVAPFTT
860 870 880 890 900
KIKGHEVERE NYSRVVPSSS SPKSHAIKQD KDVDRSVSEI YKMKHSVPQS
910 920 930 940 950
LPQSNYFTTL SNSVVNEPPR SYPSKEVSNI YTEKQNNNLS ATANPQTHSF
960 970 980 990 1000
ISSLSKPPPL IKHQPESESL VGKIPDHLPH QSASHSVTTF RSDCRSPTHL
1010 1020 1030 1040 1050
TVSSTNALRS MPALHRAPVF HPPIHHSLER KESSYSSLSP PTLTPVMPVN
1060 1070 1080 1090 1100
AGGKVQESQK PPTLIPEPKD SQSNFKNSSD QSLTEMWRSN NNLNREKAEW
1110 1120 1130 1140 1150
PVEKSSGKSQ AAVASVIVRP PSSTKVDSVP SVPLASKDRV CERSSSGANK
1160 1170 1180 1190 1200
TDYLKPEAGE TGRIILPNVN LESAHVKSEK NFEAVSQGNV PVSVMSAVNV
1210 1220 1230 1240 1250
VSTTKADVFT SAATTTSVSS LSSAETSYSL SNTISASTPF ECTSSKSVVS
1260 1270 1280 1290 1300
QAVAQAKDCT VSTAVPGTLA CSKTGSAVQP GSGFSGTTDF IHLKKHKAAL
1310 1320 1330 1340 1350
AAAQFKNSSV SEAELNTVRN QTVAASLPLD STMTCTASNK AISVGNGPAA
1360 1370 1380 1390 1400
QSSQPNYHTK LKKAWLTRHS EEDKNTNKME NSGNSVSEII KPCSVNLIAS
1410 1420 1430 1440 1450
TSNDIENRAD GRVAVDKYGR DEKVSRRKAK RTYESGSESG DSDESESKSE
1460 1470 1480 1490 1500
QRTKRQPKPT YKKKQNDLQK RKGEVEEDSK PNGVLSRSAK DKSKLKLQNS
1510 1520 1530 1540 1550
NSAGVPRSVL KDWRKVKKLK QTGESFLQDD SCCEIGPNLQ KCRECRLIRS
1560 1570 1580 1590 1600
KKGEESTHSP VFCRFYYFRR LSFSKNGVVR IDGFSSPDQY DDEAMSLWTH
1610 1620 1630 1640 1650
ENYEDDEVDV ETSKYILDII GDKFCQLVTS EKTALSWVKK DAKIAWKRAV
1660 1670 1680 1690 1700
RGVREMCDAC EATLFNVHWV CRKCGFVACL DCYKAKERKS SRDKELYAWM
1710 1720 1730 1740 1750
KCVKGQPHDH KHLMLTQIIP GSVLTDLLDA MHILREKYGI KSHCHCTNRQ
1760 1770 1780 1790 1800
NLQGGNVPTM NGVSQVLQNV LHHSNKTSVS LPESQQQNSP QKSQTNGNSS
1810 1820 1830 1840 1850
PGSASTDSRL TPPESQSPLH WLADLAEQKS REEKQENKEF TLEREIKEDG
1860 1870 1880 1890 1900
DQDASDSPNG STSPPASQSN EQGSTLRDLL TTTAGKLRVG STDAGIAFAP
1910 1920 1930 1940 1950
VYSMGTSSGK GGRTMPNILD DIIASVVENK IPPNKTSKIN IKSEPNEEPK
1960 1970 1980 1990 2000
ESSLPATDES NKSYRDIPHS WICDQHILWL KDYKNSNNWK LFKECWKQGQ
2010 2020 2030 2040 2050
PAVVSGVHKK MNISLWKAES ISLDFGDHQA DLLNCKDSIV SNANVKEFWD
2060 2070 2080 2090 2100
GFEEVSKRQK NKGGETVVLK LKDCPSGEDF KAMMPTRYED FLRCLPLPEY
2110 2120 2130 2140 2150
CNPEGKFNLA SHLPGFFVRP DLGPRLCSAY GVAAAKDHDI GTTNLHIEAS
2160 2170 2180 2190 2200
DVVNVLVYVG IAKGNGVLSK AGILKKFEEE ELDDVLRKRL KDSSEIPGAL
2210 2220 2230 2240 2250
WHIYAGKDVD KIREFLQKIS KEQGLEVLPE HDPIRDQSWY VNRKLRQRLL
2260 2270 2280 2290 2300
EEYGVRACTL IQFLGDAIVL PAGTLHQVQN FHSCVQVTED FVSPEHLVQS
2310 2320 2330 2340 2350
FHLTQELRLL KEEINYDDKL QVKNILYHAV KEMVRALKMH EDEVEDMEDT
Length:2,350
Mass (Da):260,639
Last modified:July 27, 2011 - v3
Checksum:iB17F6FAEB48FBE73
GO

Sequence cautioni

The sequence AAH68318.1 differs from that shown.Aberrant splicing.Curated
The sequence AAH68318.1 differs from that shown. Reason: Frameshift at position 1075. Curated
The sequence BAC36783.1 differs from that shown. Reason: Erroneous termination at position 2326. Translated as Leu.Curated
The sequence BAC38410.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAD32440.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti1506 – 15061P → S in AAH68318 (PubMed:15489334).Curated
Sequence conflicti1715 – 17151L → P in BAD32440 (PubMed:15368895).Curated
Sequence conflicti2189 – 21891R → I in BAD32440 (PubMed:15368895).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK173162 mRNA. Translation: BAD32440.1. Different initiation.
AC155712 Genomic DNA. No translation available.
AC156272 Genomic DNA. No translation available.
AK077400 mRNA. Translation: BAC36783.1. Sequence problems.
AK082106 mRNA. Translation: BAC38410.1. Different initiation.
AK085500 mRNA. Translation: BAC39458.1.
BC068318 mRNA. Translation: AAH68318.1. Sequence problems.
CCDSiCCDS56708.1.
RefSeqiNP_001229325.1. NM_001242396.1.
XP_006513104.1. XM_006513041.1.
XP_006513105.1. XM_006513042.2.
UniGeneiMm.23846.

Genome annotation databases

EnsembliENSMUST00000173689; ENSMUSP00000133700; ENSMUSG00000037876.
GeneIDi108829.
KEGGimmu:108829.
UCSCiuc007fls.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK173162 mRNA. Translation: BAD32440.1. Different initiation.
AC155712 Genomic DNA. No translation available.
AC156272 Genomic DNA. No translation available.
AK077400 mRNA. Translation: BAC36783.1. Sequence problems.
AK082106 mRNA. Translation: BAC38410.1. Different initiation.
AK085500 mRNA. Translation: BAC39458.1.
BC068318 mRNA. Translation: AAH68318.1. Sequence problems.
CCDSiCCDS56708.1.
RefSeqiNP_001229325.1. NM_001242396.1.
XP_006513104.1. XM_006513041.1.
XP_006513105.1. XM_006513042.2.
UniGeneiMm.23846.

3D structure databases

ProteinModelPortaliQ69ZK6.
SMRiQ69ZK6. Positions 1967-2307.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi224438. 3 interactions.
IntActiQ69ZK6. 1 interaction.
STRINGi10090.ENSMUSP00000056227.

PTM databases

iPTMnetiQ69ZK6.
PhosphoSiteiQ69ZK6.

Proteomic databases

EPDiQ69ZK6.
MaxQBiQ69ZK6.
PaxDbiQ69ZK6.
PRIDEiQ69ZK6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000173689; ENSMUSP00000133700; ENSMUSG00000037876.
GeneIDi108829.
KEGGimmu:108829.
UCSCiuc007fls.2. mouse.

Organism-specific databases

CTDi221037.
MGIiMGI:1918614. Jmjd1c.
RougeiSearch...

Phylogenomic databases

eggNOGiKOG1356. Eukaryota.
ENOG410XTAA. LUCA.
GeneTreeiENSGT00530000063039.
HOGENOMiHOG000113130.
HOVERGENiHBG079631.
InParanoidiQ69ZK6.
KOiK11449.
TreeFamiTF324723.

Enzyme and pathway databases

ReactomeiR-MMU-983231. Factors involved in megakaryocyte development and platelet production.

Miscellaneous databases

ChiTaRSiJmjd1c. mouse.
PROiQ69ZK6.
SOURCEiSearch...

Gene expression databases

BgeeiQ69ZK6.
CleanExiMM_JMJD1C.
ExpressionAtlasiQ69ZK6. baseline and differential.
GenevisibleiQ69ZK6. MM.

Family and domain databases

InterProiIPR003347. JmjC_dom.
[Graphical view]
PfamiPF02373. JmjC. 1 hit.
[Graphical view]
SMARTiSM00558. JmjC. 1 hit.
[Graphical view]
PROSITEiPS51184. JMJC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
    Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Seino S., Nishimura M., Kaisho T., Hoshino K., Kitamura H., Nagase T., Ohara O., Koga H.
    DNA Res. 11:205-218(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Embryonic intestine.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-141; 1112-1832 AND 1967-2350.
    Strain: C57BL/6J.
    Tissue: Cerebellum, Head and Kidney.
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 968-2350.
    Strain: C57BL/6J.
    Tissue: Embryonic germ cell.
  5. Lubec G., Sunyer B., Chen W.-Q.
    Submitted (JAN-2009) to UniProtKB
    Cited for: PROTEIN SEQUENCE OF 1032-1054, IDENTIFICATION BY MASS SPECTROMETRY.
    Strain: OF1.
    Tissue: Hippocampus.
  6. "The phagosomal proteome in interferon-gamma-activated macrophages."
    Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
    Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  7. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-135; SER-138; SER-294 AND SER-471, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Kidney, Spleen and Testis.

Entry informationi

Entry nameiJHD2C_MOUSE
AccessioniPrimary (citable) accession number: Q69ZK6
Secondary accession number(s): E9QMM8
, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: July 27, 2011
Last modified: June 8, 2016
This is version 96 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.