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Q69Z52

- Q69Z52_MOUSE

UniProt

Q69Z52 - Q69Z52_MOUSE

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Protein
Submitted name: MKIAA1973 protein
Gene
Grin3a, mKIAA1973
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. N-methyl-D-aspartate selective glutamate receptor activity Source: MGI
  2. calcium channel activity Source: MGI
  3. extracellular-glutamate-gated ion channel activity Source: RefGenome
  4. protein binding Source: MGI

GO - Biological processi

  1. calcium ion transmembrane transport Source: GOC
  2. calcium ion transport Source: MGI
  3. dendrite development Source: MGI
  4. ion transmembrane transport Source: GOC
  5. ionotropic glutamate receptor signaling pathway Source: GOC
  6. prepulse inhibition Source: MGI
  7. synaptic transmission, glutamatergic Source: RefGenome
Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Ligand-gated ion channelSAAS annotations, ReceptorSAAS annotations

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
MKIAA1973 proteinImported
Gene namesi
Name:Grin3aImported
Synonyms:mKIAA1973Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1933206. Grin3a.

Subcellular locationi

GO - Cellular componenti

  1. N-methyl-D-aspartate selective glutamate receptor complex Source: RefGenome
  2. cell junction Source: UniProtKB-KW
  3. dendrite Source: RefGenome
  4. neuronal cell body Source: MGI
  5. postsynaptic membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotations, Membrane, Postsynaptic cell membraneSAAS annotations, Synapse

PTM / Processingi

PTM databases

PhosphoSiteiQ69Z52.

Expressioni

Gene expression databases

ArrayExpressiQ69Z52.
BgeeiQ69Z52.
GenevestigatoriQ69Z52.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000091381.

Structurei

3D structure databases

ProteinModelPortaliQ69Z52.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

HOVERGENiHBG052634.
InParanoidiQ69Z52.

Family and domain databases

InterProiIPR019594. Glu_rcpt_Glu/Gly-bd.
IPR001320. Iontro_glu_rcpt.
IPR001508. NMDA_rcpt.
IPR028082. Peripla_BP_I.
IPR001638. SBP_bac_3.
[Graphical view]
PfamiPF00060. Lig_chan. 1 hit.
PF00497. SBP_bac_3. 1 hit.
[Graphical view]
PRINTSiPR00177. NMDARECEPTOR.
SMARTiSM00918. Lig_chan-Glu_bd. 1 hit.
SM00079. PBPe. 1 hit.
[Graphical view]
SUPFAMiSSF53822. SSF53822. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q69Z52-1 [UniParc]FASTAAdd to Basket

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RGPPGSRKLG EGAGTETLWP RDALLFAVEN LNRVEGLLPY NLSLEVVMAI     50
EAGLGDLPLM PFSSPSSPWS SDPFSFLQSV CHTVVVQGVS ALLAFPQSQG 100
EMMELDLVSS VLHIPVLSIV RHEFPRESQN PLHLQLSLEN SLSSDADVTV 150
SILTMNNWYN FSLLLCQEDW NITDFLLLTE NNSKFHLESI INITANLSST 200
KDLLSFLQVQ LENIRNSTPT MVMFGCDMGS IRQIFEMSTQ FGLSPPDLHW 250
VLGDSQNVEE LRTEGLPLGL IAHGKTTQSV FEYYVQDAME LVARAVATAT 300
MIQPELALLP STMNCMDVKT TNLTSGQYLS RFLANTTFRG LSGSIKVKGS 350
TIVSSENNFF IWNLQYDPMG KPMWTRLGSW QGGRIVMDSG IWPEQAQRHK 400
THFHHPNKLH LRVVTLIEHP FVFTREVDDE GLCPAGQLCL DPMTNDSSIL 450
DSLFSSLHSS NDTVPIKFKK CCYGYCIDLL EQLAEDMNFD FDLYIVGDGK 500
YGAWKNGHWT GLVGDLLSGT ANMAVTSFSI NTARSQVIDF TSPFFSTSLG 550
ILVRTRDTAA PIGAFMWPLH WTMWLGIFVA LHITAIFLTL YEWKSPFGMT 600
PKGRNRNKVF SFSSALNVCY ALLFGRTAAI KPPKCWTGRF LMNLWAIFCM 650
FCLSTYTANL AAVMVGEKIY EELSGIHDPK LHHPSQGFRF GTVRESSAED 700
YVRQSFPEMH EYMRRYNVPA TPDGVQYLKN DPEKLDAFIM DKALLDYEVS 750
IDADCKLLTV GKPFAIEGYG IGLPPNSPLT SNISELISQY KSHGFMDVLH 800
DKWYKVVPCG KRSFAVTETL QMGIKHFSGL FVLLCIGFGL SILTTIGEHI 850
VYRLLLPRIK NKSKLQYWLH TSQRFHRALN TSFVEEKQPC SKTKRVEKSR 900
WRRWTCKTEG DSELSLFPRS NMGPQQLMVW NTSNLSHDNQ RKYIFNDEEG 950
QNQLGTQTHQ DIPLPPRRRE LPASLTTNGK ADSLNVARNS VMQELSELEK 1000
QIQVIRQELQ LAVSRKTELE EYQRTNRTCE S 1031
Length:1,031
Mass (Da):116,392
Last modified:September 13, 2004 - v1
Checksum:i81767ACCAAEDA79F
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK173314 mRNA. Translation: BAD32592.1.
UniGeneiMm.440095.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK173314 mRNA. Translation: BAD32592.1 .
UniGenei Mm.440095.

3D structure databases

ProteinModelPortali Q69Z52.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000091381.

Chemistry

BindingDBi Q69Z52.

PTM databases

PhosphoSitei Q69Z52.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:1933206. Grin3a.

Phylogenomic databases

HOVERGENi HBG052634.
InParanoidi Q69Z52.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

ArrayExpressi Q69Z52.
Bgeei Q69Z52.
Genevestigatori Q69Z52.

Family and domain databases

InterProi IPR019594. Glu_rcpt_Glu/Gly-bd.
IPR001320. Iontro_glu_rcpt.
IPR001508. NMDA_rcpt.
IPR028082. Peripla_BP_I.
IPR001638. SBP_bac_3.
[Graphical view ]
Pfami PF00060. Lig_chan. 1 hit.
PF00497. SBP_bac_3. 1 hit.
[Graphical view ]
PRINTSi PR00177. NMDARECEPTOR.
SMARTi SM00918. Lig_chan-Glu_bd. 1 hit.
SM00079. PBPe. 1 hit.
[Graphical view ]
SUPFAMi SSF53822. SSF53822. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
    Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Seino S., Nishimura M., Kaisho T., Hoshino K., Kitamura H., Nagase T., Ohara O., Koga H.
    DNA Res. 11:205-218(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Fetal brainImported.

Entry informationi

Entry nameiQ69Z52_MOUSE
AccessioniPrimary (citable) accession number: Q69Z52
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2004
Last sequence update: September 13, 2004
Last modified: June 11, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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