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Q69Z52

- Q69Z52_MOUSE

UniProt

Q69Z52 - Q69Z52_MOUSE

Protein
Submitted name:

MKIAA1973 protein

Gene

Grin3a

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 69 (01 Oct 2014)
      Sequence version 1 (13 Sep 2004)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. calcium channel activity Source: MGI
    2. extracellular-glutamate-gated ion channel activity Source: RefGenome
    3. N-methyl-D-aspartate selective glutamate receptor activity Source: MGI
    4. protein binding Source: MGI

    GO - Biological processi

    1. calcium ion transmembrane transport Source: GOC
    2. calcium ion transport Source: MGI
    3. dendrite development Source: MGI
    4. ionotropic glutamate receptor signaling pathway Source: GOC
    5. ion transmembrane transport Source: GOC
    6. prepulse inhibition Source: MGI
    7. synaptic transmission, glutamatergic Source: RefGenome

    Keywords - Molecular functioni

    Ion channel, Ligand-gated ion channelSAAS annotation, ReceptorSAAS annotation

    Keywords - Biological processi

    Ion transport, Transport

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    MKIAA1973 proteinImported
    Gene namesi
    Name:Grin3aImported
    Synonyms:mKIAA1973Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:1933206. Grin3a.

    Subcellular locationi

    GO - Cellular componenti

    1. cell junction Source: UniProtKB-KW
    2. dendrite Source: RefGenome
    3. neuronal cell body Source: MGI
    4. N-methyl-D-aspartate selective glutamate receptor complex Source: RefGenome
    5. postsynaptic membrane Source: MGI

    Keywords - Cellular componenti

    Cell junction, Cell membraneSAAS annotation, Membrane, Postsynaptic cell membraneSAAS annotation, Synapse

    PTM / Processingi

    PTM databases

    PhosphoSiteiQ69Z52.

    Expressioni

    Gene expression databases

    ArrayExpressiQ69Z52.
    BgeeiQ69Z52.
    GenevestigatoriQ69Z52.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000091381.

    Structurei

    3D structure databases

    ProteinModelPortaliQ69Z52.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    HOVERGENiHBG052634.
    InParanoidiQ69Z52.

    Family and domain databases

    InterProiIPR019594. Glu_rcpt_Glu/Gly-bd.
    IPR001320. Iontro_glu_rcpt.
    IPR001508. NMDA_rcpt.
    IPR028082. Peripla_BP_I.
    IPR001638. SBP_bac_3.
    [Graphical view]
    PfamiPF00060. Lig_chan. 1 hit.
    PF00497. SBP_bac_3. 1 hit.
    [Graphical view]
    PRINTSiPR00177. NMDARECEPTOR.
    SMARTiSM00918. Lig_chan-Glu_bd. 1 hit.
    SM00079. PBPe. 1 hit.
    [Graphical view]
    SUPFAMiSSF53822. SSF53822. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    Q69Z52-1 [UniParc]FASTAAdd to Basket

    « Hide

    RGPPGSRKLG EGAGTETLWP RDALLFAVEN LNRVEGLLPY NLSLEVVMAI     50
    EAGLGDLPLM PFSSPSSPWS SDPFSFLQSV CHTVVVQGVS ALLAFPQSQG 100
    EMMELDLVSS VLHIPVLSIV RHEFPRESQN PLHLQLSLEN SLSSDADVTV 150
    SILTMNNWYN FSLLLCQEDW NITDFLLLTE NNSKFHLESI INITANLSST 200
    KDLLSFLQVQ LENIRNSTPT MVMFGCDMGS IRQIFEMSTQ FGLSPPDLHW 250
    VLGDSQNVEE LRTEGLPLGL IAHGKTTQSV FEYYVQDAME LVARAVATAT 300
    MIQPELALLP STMNCMDVKT TNLTSGQYLS RFLANTTFRG LSGSIKVKGS 350
    TIVSSENNFF IWNLQYDPMG KPMWTRLGSW QGGRIVMDSG IWPEQAQRHK 400
    THFHHPNKLH LRVVTLIEHP FVFTREVDDE GLCPAGQLCL DPMTNDSSIL 450
    DSLFSSLHSS NDTVPIKFKK CCYGYCIDLL EQLAEDMNFD FDLYIVGDGK 500
    YGAWKNGHWT GLVGDLLSGT ANMAVTSFSI NTARSQVIDF TSPFFSTSLG 550
    ILVRTRDTAA PIGAFMWPLH WTMWLGIFVA LHITAIFLTL YEWKSPFGMT 600
    PKGRNRNKVF SFSSALNVCY ALLFGRTAAI KPPKCWTGRF LMNLWAIFCM 650
    FCLSTYTANL AAVMVGEKIY EELSGIHDPK LHHPSQGFRF GTVRESSAED 700
    YVRQSFPEMH EYMRRYNVPA TPDGVQYLKN DPEKLDAFIM DKALLDYEVS 750
    IDADCKLLTV GKPFAIEGYG IGLPPNSPLT SNISELISQY KSHGFMDVLH 800
    DKWYKVVPCG KRSFAVTETL QMGIKHFSGL FVLLCIGFGL SILTTIGEHI 850
    VYRLLLPRIK NKSKLQYWLH TSQRFHRALN TSFVEEKQPC SKTKRVEKSR 900
    WRRWTCKTEG DSELSLFPRS NMGPQQLMVW NTSNLSHDNQ RKYIFNDEEG 950
    QNQLGTQTHQ DIPLPPRRRE LPASLTTNGK ADSLNVARNS VMQELSELEK 1000
    QIQVIRQELQ LAVSRKTELE EYQRTNRTCE S 1031
    Length:1,031
    Mass (Da):116,392
    Last modified:September 13, 2004 - v1
    Checksum:i81767ACCAAEDA79F
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK173314 mRNA. Translation: BAD32592.1.
    UniGeneiMm.440095.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK173314 mRNA. Translation: BAD32592.1 .
    UniGenei Mm.440095.

    3D structure databases

    ProteinModelPortali Q69Z52.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000091381.

    Chemistry

    BindingDBi Q69Z52.

    PTM databases

    PhosphoSitei Q69Z52.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:1933206. Grin3a.

    Phylogenomic databases

    HOVERGENi HBG052634.
    InParanoidi Q69Z52.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q69Z52.
    Bgeei Q69Z52.
    Genevestigatori Q69Z52.

    Family and domain databases

    InterProi IPR019594. Glu_rcpt_Glu/Gly-bd.
    IPR001320. Iontro_glu_rcpt.
    IPR001508. NMDA_rcpt.
    IPR028082. Peripla_BP_I.
    IPR001638. SBP_bac_3.
    [Graphical view ]
    Pfami PF00060. Lig_chan. 1 hit.
    PF00497. SBP_bac_3. 1 hit.
    [Graphical view ]
    PRINTSi PR00177. NMDARECEPTOR.
    SMARTi SM00918. Lig_chan-Glu_bd. 1 hit.
    SM00079. PBPe. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53822. SSF53822. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Seino S., Nishimura M., Kaisho T., Hoshino K., Kitamura H., Nagase T., Ohara O., Koga H.
      DNA Res. 11:205-218(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Fetal brainImported.

    Entry informationi

    Entry nameiQ69Z52_MOUSE
    AccessioniPrimary (citable) accession number: Q69Z52
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 13, 2004
    Last sequence update: September 13, 2004
    Last modified: October 1, 2014
    This is version 69 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)