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Q69YG0 (TMM42_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Transmembrane protein 42
Gene names
Name:TMEM42
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length159 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 159159Transmembrane protein 42
PRO_0000284495

Regions

Transmembrane37 – 5721Helical; Potential
Transmembrane59 – 7921Helical; Potential
Transmembrane100 – 12021Helical; Potential
Transmembrane124 – 14421Helical; Potential

Experimental info

Sequence conflict651V → VV in CAH10689. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q69YG0 [UniParc].

Last modified April 17, 2007. Version 2.
Checksum: A8572BF4BC9CF44E

FASTA15916,991
        10         20         30         40         50         60 
MAERPGPPGG AVSATAYPDT PAEFPPHLQA GAMRRRFWGV FNCLCAGAFG ALAAASAKLA 

        70         80         90        100        110        120 
FGSEVSMGLC VLGIIVMAST NSLMWTFFSR GLSFSMSSAI ASVTVTFSNI LSSAFLGYVL 

       130        140        150 
YGECQEVLWW GGVFLILCGL TLIHRKLPPT WKPLPHKQQ 

« Hide

References

[1]"The full-ORF clone resource of the German cDNA consortium."
Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I.
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Testis.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Cervix.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL834253 mRNA. Translation: CAH10689.1.
BC019851 mRNA. Translation: AAH19851.1.
RefSeqNP_653239.1. NM_144638.1.
UniGeneHs.646856.

3D structure databases

ProteinModelPortalQ69YG0.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ69YG0.

Polymorphism databases

DMDM145572734.

Proteomic databases

PaxDbQ69YG0.
PRIDEQ69YG0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000302392; ENSP00000306564; ENSG00000169964.
GeneID131616.
KEGGhsa:131616.
UCSCuc003cnz.3. human.

Organism-specific databases

CTD131616.
GeneCardsGC03P044907.
H-InvDBHIX0200526.
HGNCHGNC:28444. TMEM42.
HPAHPA052569.
neXtProtNX_Q69YG0.
PharmGKBPA134914008.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG16283.
HOGENOMHOG000154645.
HOVERGENHBG098258.
OMAFGSEVNM.
OrthoDBEOG78WKW2.
PhylomeDBQ69YG0.
TreeFamTF336306.

Gene expression databases

BgeeQ69YG0.
GenevestigatorQ69YG0.

Family and domain databases

ProtoNetSearch...

Other

GenomeRNAi131616.
NextBio82954.
PROQ69YG0.

Entry information

Entry nameTMM42_HUMAN
AccessionPrimary (citable) accession number: Q69YG0
Secondary accession number(s): Q8WUQ6
Entry history
Integrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: April 17, 2007
Last modified: February 19, 2014
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 3

Human chromosome 3: entries, gene names and cross-references to MIM