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Protein

Transmembrane protein 42

Gene

TMEM42

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 42
Gene namesi
Name:TMEM42
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000169964.5
HGNCiHGNC:28444 TMEM42
neXtProtiNX_Q69YG0

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei37 – 57HelicalSequence analysisAdd BLAST21
Transmembranei59 – 79HelicalSequence analysisAdd BLAST21
Transmembranei100 – 120HelicalSequence analysisAdd BLAST21
Transmembranei124 – 144HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000169964
PharmGKBiPA134914008

Polymorphism and mutation databases

BioMutaiTMEM42
DMDMi145572734

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002844951 – 159Transmembrane protein 42Add BLAST159

Proteomic databases

PaxDbiQ69YG0
PeptideAtlasiQ69YG0
PRIDEiQ69YG0

PTM databases

iPTMnetiQ69YG0
PhosphoSitePlusiQ69YG0

Expressioni

Gene expression databases

BgeeiENSG00000169964
GenevisibleiQ69YG0 HS

Organism-specific databases

HPAiHPA052569

Interactioni

Protein-protein interaction databases

BioGridi126290, 1 interactor
IntActiQ69YG0, 10 interactors

Structurei

3D structure databases

ProteinModelPortaliQ69YG0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IWPB Eukaryota
ENOG410XXKU LUCA
GeneTreeiENSGT00390000012690
HOGENOMiHOG000154645
HOVERGENiHBG098258
InParanoidiQ69YG0
OMAiFGSEVNM
OrthoDBiEOG091G11KM
PhylomeDBiQ69YG0
TreeFamiTF336306

Sequencei

Sequence statusi: Complete.

Q69YG0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAERPGPPGG AVSATAYPDT PAEFPPHLQA GAMRRRFWGV FNCLCAGAFG
60 70 80 90 100
ALAAASAKLA FGSEVSMGLC VLGIIVMAST NSLMWTFFSR GLSFSMSSAI
110 120 130 140 150
ASVTVTFSNI LSSAFLGYVL YGECQEVLWW GGVFLILCGL TLIHRKLPPT

WKPLPHKQQ
Length:159
Mass (Da):16,991
Last modified:April 17, 2007 - v2
Checksum:iA8572BF4BC9CF44E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti65V → VV in CAH10689 (PubMed:17974005).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL834253 mRNA Translation: CAH10689.1
BC019851 mRNA Translation: AAH19851.1
CCDSiCCDS2722.1
RefSeqiNP_653239.1, NM_144638.2
UniGeneiHs.646856

Genome annotation databases

EnsembliENST00000302392; ENSP00000306564; ENSG00000169964
ENST00000626748; ENSP00000486141; ENSG00000280516
GeneIDi131616
KEGGihsa:131616
UCSCiuc003cnz.4 human

Similar proteinsi

Entry informationi

Entry nameiTMM42_HUMAN
AccessioniPrimary (citable) accession number: Q69YG0
Secondary accession number(s): Q8WUQ6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: April 17, 2007
Last modified: April 25, 2018
This is version 92 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
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