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Q69YG0

- TMM42_HUMAN

UniProt

Q69YG0 - TMM42_HUMAN

Protein

Transmembrane protein 42

Gene

TMEM42

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
  1. Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transmembrane protein 42
    Gene namesi
    Name:TMEM42
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 3

    Organism-specific databases

    HGNCiHGNC:28444. TMEM42.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134914008.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 159159Transmembrane protein 42PRO_0000284495Add
    BLAST

    Proteomic databases

    PaxDbiQ69YG0.
    PRIDEiQ69YG0.

    PTM databases

    PhosphoSiteiQ69YG0.

    Expressioni

    Gene expression databases

    BgeeiQ69YG0.
    GenevestigatoriQ69YG0.

    Organism-specific databases

    HPAiHPA052569.

    Structurei

    3D structure databases

    ProteinModelPortaliQ69YG0.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei37 – 5721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei59 – 7921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei100 – 12021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei124 – 14421HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG16283.
    HOGENOMiHOG000154645.
    HOVERGENiHBG098258.
    OMAiFGSEVNM.
    OrthoDBiEOG78WKW2.
    PhylomeDBiQ69YG0.
    TreeFamiTF336306.

    Sequencei

    Sequence statusi: Complete.

    Q69YG0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAERPGPPGG AVSATAYPDT PAEFPPHLQA GAMRRRFWGV FNCLCAGAFG    50
    ALAAASAKLA FGSEVSMGLC VLGIIVMAST NSLMWTFFSR GLSFSMSSAI 100
    ASVTVTFSNI LSSAFLGYVL YGECQEVLWW GGVFLILCGL TLIHRKLPPT 150
    WKPLPHKQQ 159
    Length:159
    Mass (Da):16,991
    Last modified:April 17, 2007 - v2
    Checksum:iA8572BF4BC9CF44E
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti65 – 651V → VV in CAH10689. (PubMed:17974005)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL834253 mRNA. Translation: CAH10689.1.
    BC019851 mRNA. Translation: AAH19851.1.
    CCDSiCCDS2722.1.
    RefSeqiNP_653239.1. NM_144638.1.
    UniGeneiHs.646856.

    Genome annotation databases

    EnsembliENST00000302392; ENSP00000306564; ENSG00000169964.
    GeneIDi131616.
    KEGGihsa:131616.
    UCSCiuc003cnz.3. human.

    Polymorphism databases

    DMDMi145572734.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL834253 mRNA. Translation: CAH10689.1 .
    BC019851 mRNA. Translation: AAH19851.1 .
    CCDSi CCDS2722.1.
    RefSeqi NP_653239.1. NM_144638.1.
    UniGenei Hs.646856.

    3D structure databases

    ProteinModelPortali Q69YG0.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q69YG0.

    Polymorphism databases

    DMDMi 145572734.

    Proteomic databases

    PaxDbi Q69YG0.
    PRIDEi Q69YG0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000302392 ; ENSP00000306564 ; ENSG00000169964 .
    GeneIDi 131616.
    KEGGi hsa:131616.
    UCSCi uc003cnz.3. human.

    Organism-specific databases

    CTDi 131616.
    GeneCardsi GC03P044907.
    H-InvDB HIX0200526.
    HGNCi HGNC:28444. TMEM42.
    HPAi HPA052569.
    neXtProti NX_Q69YG0.
    PharmGKBi PA134914008.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG16283.
    HOGENOMi HOG000154645.
    HOVERGENi HBG098258.
    OMAi FGSEVNM.
    OrthoDBi EOG78WKW2.
    PhylomeDBi Q69YG0.
    TreeFami TF336306.

    Miscellaneous databases

    GenomeRNAii 131616.
    NextBioi 82954.
    PROi Q69YG0.

    Gene expression databases

    Bgeei Q69YG0.
    Genevestigatori Q69YG0.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Testis.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Cervix.

    Entry informationi

    Entry nameiTMM42_HUMAN
    AccessioniPrimary (citable) accession number: Q69YG0
    Secondary accession number(s): Q8WUQ6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 17, 2007
    Last sequence update: April 17, 2007
    Last modified: October 1, 2014
    This is version 65 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 3
      Human chromosome 3: entries, gene names and cross-references to MIM

    External Data

    Dasty 3