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Q69XQ6 (KPRS2_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribose-phosphate pyrophosphokinase 2, chloroplastic
EC=2.7.6.1
Alternative name(s):
Phosphoribosyl pyrophosphate synthase 2
Gene names
Ordered Locus Names:Os06g0617800, LOC_Os06g41360
ORF Names:P0012B02.3-1, P0012B02.3-2
OrganismOryza sativa subsp. japonica (Rice)
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate.

Cofactor

Binds 1 magnesium ion per subunit By similarity.

Subcellular location

Plastid › chloroplast Potential.

Sequence similarities

Belongs to the ribose-phosphate pyrophosphokinase family.

Sequence caution

The sequence BAD35420.1 differs from that shown. Reason: Erroneous gene model prediction.

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 2 (identifier: Q69XQ6-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Note: May be due to an intron retention. No experimental confirmation available.
Isoform 1 (identifier: Q69XQ6-2)

The sequence of this isoform differs from the canonical sequence as follows:
     340-399: SPPAIERLSG...RDGSVSSIFQ → RFGSWFIVTS...DQYKNDRVEQ

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 3232Chloroplast Potential
Chain33 – 399367Ribose-phosphate pyrophosphokinase 2, chloroplastic
PRO_0000141098

Regions

Region299 – 31416Binding of phosphoribosylpyrophosphate Potential

Sites

Metal binding2141Magnesium By similarity
Metal binding2161Magnesium By similarity
Metal binding2251Magnesium By similarity
Metal binding2291Magnesium By similarity

Natural variations

Alternative sequence340 – 39960SPPAI…SSIFQ → RFGSWFIVTSMIHVIVLIHW LVAKEPCYGMIRQIGFMFDQ YKNDRVEQ in isoform 1.
VSP_013704

Sequences

Sequence LengthMass (Da)Tools
Isoform 2 [UniParc].

Last modified May 10, 2005. Version 2.
Checksum: 275952D85DB19C06

FASTA39943,086
        10         20         30         40         50         60 
MAAKAAALSS SPFVSSRRLS SPAASLRART PRCVMGSEQV RVVVEEEGKT KKRMGVAEPR 

        70         80         90        100        110        120 
SAPPAVWTPR APAQEARLAA LRTDGRDSRL KIFSGTANRP LAQEIASYLG VDLGKVLIKR 

       130        140        150        160        170        180 
FADGEIYVQL QESVRGCDVF LVQPTCSPVN ENLMELFVMI DACRRASARS ITVVIPYFGY 

       190        200        210        220        230        240 
ARADRKAQGR EAITAKLSAN LLTEAGSDRV IVCDIHSTQA LGYFDIPVDH IHGQPVILDY 

       250        260        270        280        290        300 
LASKTISKDL VVVSPDVGGV VRARAFAKKL SDAPLAIVDK RRQGHNMSEV MHLIGDVKGK 

       310        320        330        340        350        360 
VAIMVDDMID TAGTITSAAA LLKQEGAEAV YACSTHAVFS PPAIERLSGG IFEEVIVTNS 

       370        380        390 
ILLPEHKCFP QLTVLSMANL VAETIWHVHR DGSVSSIFQ

« Hide

Isoform 1 [UniParc].

Checksum: BD10C47B2E27B288
Show »

FASTA38742,274

References

[1]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed: 16100779] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed: 12869764] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
Strain: cv. Nipponbare.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP003609 Genomic DNA. Translation: BAD35420.1. Sequence problems.
AP003609 Genomic DNA. Translation: BAD35421.1.
AK065878 mRNA. No translation available.
AK067505 mRNA. No translation available.
AK068485 mRNA. No translation available.
RefSeqNP_001058081.1. NM_001064616.1.
UniGeneOs.91644.

3D structure databases

ProteinModelPortalQ69XQ6.
SMRQ69XQ6. Positions 90-399.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ69XQ6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsLOC_Os06g41360.1; LOC_Os06g41360.1; LOC_Os06g41360.
LOC_Os06g41360.2; LOC_Os06g41360.2; LOC_Os06g41360.
GeneID4341535.
KEGGosa:4341535.

Organism-specific databases

GrameneQ69XQ6.

Phylogenomic databases

GeneTreeEPGT00070000029078.
OMANIILFGM.
ProtClustDBPLN02369.

Family and domain databases

InterProIPR000842. PRib_PP_synth_CS.
IPR000836. PRibTrfase.
IPR005946. Rib-P_diPkinase.
[Graphical view]
KOK00948.
PfamPF00156. Pribosyltran. 1 hit.
[Graphical view]
TIGRFAMsTIGR01251. RibP_PPkin. 1 hit.
PROSITEPS00114. PRPP_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKPRS2_ORYSJ
AccessionPrimary (citable) accession number: Q69XQ6
Secondary accession number(s): Q69XQ7
Entry history
Integrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: May 10, 2005
Last modified: November 16, 2011
This is version 52 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

SIMILARITY comments

Index of protein domains and families

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