Reviewed, UniProtKB/Swiss-Prot Q69XK5 (CESAB_ORYSJ)

Names and origin

Protein names

Recommended name:
    Putative cellulose synthase A catalytic subunit 11 [UDP-forming]
    EC=2.4.1.12
Alternative name(s):
    OsCesA11

Gene names

Name:	CESA11
Ordered Locus Names:	LOC_Os06g39970
ORF Names:	P0486H12.12, P0457B11.25

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	860 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation By similarity.
Catalytic activity	UDP-glucose + (1,4-beta-D-glucosyl)(n) = UDP + (1,4-beta-D-glucosyl)(n+1).
Cofactor	Binds 2 zinc ions per subunit By similarity.
Pathway	Glycan metabolism; plant cellulose biosynthesis.
Subcellular location	Cell membrane; Multi-pass membrane protein Probable.
Sequence similarities	Belongs to the glycosyltransferase 2 family. Plant cellulose synthase subfamily. Contains 1 RING-type zinc finger.
Caution	Lacks the conserved zinc finger domain, which is one of the features of the CESA family. Could be the product of a pseudogene.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation Cellulose biosynthesis
Cellular component	Cell membrane Membrane
Domain	Coiled coil Transmembrane
Molecular function	Glycosyltransferase Transferase
Gene Ontology (GO)
Biological process	cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW cellulose biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	cellulose synthase (UDP-forming) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 860	860	Putative cellulose synthase A catalytic subunit 11 [UDP-forming]		PRO_0000319371
Regions
	Topological domain	1 – 43	43	Cytoplasmic Potential
	Transmembrane	44 – 64	21	Potential
	Topological domain	65 – 72	8	Extracellular Potential
	Transmembrane	73 – 93	21	Potential
	Topological domain	94 – 626	533	Cytoplasmic Potential
	Transmembrane	627 – 647	21	Potential
	Topological domain	648 – 657	10	Extracellular Potential
	Transmembrane	658 – 678	21	Potential
	Topological domain	679 – 701	23	Cytoplasmic Potential
	Transmembrane	702 – 722	21	Potential
	Topological domain	723 – 757	35	Extracellular Potential
	Transmembrane	758 – 778	21	Potential
	Topological domain	779 – 789	11	Cytoplasmic Potential
	Transmembrane	790 – 810	21	Potential
	Topological domain	811 – 823	13	Extracellular Potential
	Transmembrane	824 – 844	21	Potential
	Topological domain	845 – 860	16	Cytoplasmic Potential
	Coiled coil	223 – 249	27	Potential
Sites
	Binding site	334	1	Substrate Potential
	Binding site	336	1	Substrate Potential

Sequences

	Sequence		Length	Mass (Da)
	Q69XK5-1 [UniParc]. Last modified September 13, 2004. Version 1. Checksum: 6DFE90A6619D0488	FASTA	860	93,472
	10 20 30 40 50 60 MDGESPEIMP VECPDPEPAS SESGDDHDIP EPLSSRLSVP SGELNLYRAA VALRLVLLAA 70 80 90 100 110 120 FFRYRVTRPV ADAHALWVTS VACELWLAAS WLIAQLPKLS PANRVTYLDR LASRYEKGGE 130 140 150 160 170 180 ASRLAGVDVF VAAADAAREP PLATANTVLS VLAADYPAGG VACYVHDDGA DMLVFESLFE 190 200 210 220 230 240 AAGFARRWIP FCRRHGVEPR APELYFARGV DYLRDRAAPS FVKDRRAMKR EYEEFKVRMN 250 260 270 280 290 300 HLAARARKVP EEGWIMSDGT PWPGNNSRDH PAMIQVLLGH PGDRDVDGGE LPRLFYVSRE 310 320 330 340 350 360 KRPGFRHHGK AGAMNALLRV SAVLTNGAYV LNLDCDHCVN NSSALREAMC FMMDPVAGNR 370 380 390 400 410 420 TCFVQFALRD SGGGDSVFFD IEMKCLDGIQ GPVYVGSGCC FSRKALYGFE PAAAADDGDD 430 440 450 460 470 480 MDTAADWRRM CCFGRGKRMN AMRRSMSAVP LLDSEDDSDE QEEEEAAGRR RRLRAYRAAL 490 500 510 520 530 540 ERHFGQSPAF IASAFEEQGR RRGGDGGSPD ATVAPARSLL KEAIHVVSCA FEERTRWGKE 550 560 570 580 590 600 IGWMYGGGVA TGFRMHARGW SSAYCSPARP AFRRYARASP ADVLAGASRR AVAAMGILLS 610 620 630 640 650 660 RRHSPVWAGR RLGLLQRLGY VARASYPLAS LPLTVYCALP AVCLLTGKST FPSDVSYYDG 670 680 690 700 710 720 VLLILLLFSV AASVALELRW SRVPLRAWWR DEKLWMVTAT SASLAAVFQG ILSACTGIDV 730 740 750 760 770 780 AFSTETAASP PKRPAAGNDD GEEEAALASE ITMRWTNLLV APTSVVVANL AGVVAAVAYG 790 800 810 820 830 840 VDHGYYQSWG ALGAKLALAG WVVAHLQGFL RGLLAPRDRA PPTIAVLWSV VFVSVASLLW 850 860 VHAASFSAPT AAPTTEQPIL

References

[1]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed: 16100779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP003612 Genomic DNA. Translation: BAD32845.1. AP003615 Genomic DNA. Translation: BAD35452.1.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GT2. Glycosyltransferase Family 2.
Organism-specific databases
Gramene	Q69XK5.
Family and domain databases
InterPro	IPR005150. Cellulose_synth. [Graphical view]
Pfam	PF03552. Cellulose_synt. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CESAB_ORYSJ

Accession

Primary (citable) accession number: Q69XK5

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	September 13, 2004
Last modified:	June 16, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)