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Q69XJ4 (HMOX1_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Heme oxygenase 1, chloroplastic

EC=1.14.99.3
Alternative name(s):
Protein PHOTOPERIODIC SENSITIVITY 5
Gene names
Name:HO1
Synonyms:HY1, SE5
Ordered Locus Names:Os06g0603000, LOC_Os06g40080
ORF Names:OsJ_21897, P0486H12.31
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length289 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Catalyzes the opening of the heme ring to form the open-chain tetrapyrrole biliverdin IX with the release of iron and carbon monoxide (CO). Is a key enzyme in the synthesis of the chromophore of the phytochrome family of plant photoreceptors. Essential for photoperiod response and repression of flowering through cytochromes that inhibit flowering by affecting both HD1 and EHD1 flowering pathways. Ref.6 Ref.7

Catalytic activity

Protoheme + 3 AH2 + 3 O2 = biliverdin + Fe2+ + CO + 3 A + 3 H2O.

Subcellular location

Plastidchloroplast.

Disruption phenotype

Pale green and very early flowering phenotype and complete deficiency in photoperiodic response. Lack of photoreversible phytochromes and responses of coleoptile elongation by light pulses. Ref.6 Ref.7

Sequence similarities

Belongs to the heme oxygenase family.

Ontologies

Keywords
   Biological processPhotosynthesis
   Cellular componentChloroplast
Plastid
   DomainTransit peptide
   LigandHeme
Iron
Metal-binding
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcarotenoid biosynthetic process

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

cellular response to UV-C

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

chloroplast-nucleus signaling pathway

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

flavonoid biosynthetic process

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

heme oxidation

Inferred from sequence or structural similarity Ref.6. Source: Gramene

inflorescence development

Inferred from mutant phenotype Ref.6. Source: Gramene

photoperiodism

Inferred from mutant phenotype Ref.6. Source: Gramene

photoperiodism, flowering

Inferred from mutant phenotype Ref.7. Source: UniProtKB

photosynthesis

Inferred from electronic annotation. Source: UniProtKB-KW

phytochromobilin biosynthetic process

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

regulation of meristem growth

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Cellular_componentchloroplast

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionheme binding

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

heme oxygenase (decyclizing) activity

Inferred from sequence or structural similarity Ref.6. Source: Gramene

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 6464Chloroplast Potential
Chain65 – 289225Heme oxygenase 1, chloroplastic
PRO_0000412189

Sites

Metal binding961Iron (heme axial ligand) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q69XJ4 [UniParc].

Last modified September 13, 2004. Version 1.
Checksum: C03B0103AD2E6E91

FASTA28931,918
        10         20         30         40         50         60 
MAPAAASLTA PNALAATSLP FLHGRKSGGG GVSVHAGAPS PSRAVAVVAR RLWGSASSSR 

        70         80         90        100        110        120 
RMVVAAATAA EMAPAASGEE GKPFVEEMRA VAMRLHTKDQ AKEGEKEPQA PPVARWEPSV 

       130        140        150        160        170        180 
DGYLRFLVDS KLVFETLETI VDRAAVPWYA EFRNTGLERS EQLKKDLEWF KEQGHTIPEP 

       190        200        210        220        230        240 
SAPGTTYASY LEELAEKDSQ AFICHFYNVY FAHTAGGRMI GKKVSENILN KKELEFYKWE 

       250        260        270        280 
GNLSQLLQNV RNKLNEVASS WTREEKDHCL DETEKSFSYS GDLLRHIFT 

« Hide

References

« Hide 'large scale' references
[1]"Cloning and characterization of heme oxygenase-1 from Oryza sativa."
Xu S., Wu T.T., Lu H., Ling T.F., Xuan W., Sun Y.G., Cao Z., Shen W.B.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[3]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[4]"The genomes of Oryza sativa: a history of duplications."
Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. expand/collapse author list , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[5]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Nipponbare.
[6]"Phytochromes confer the photoperiodic control of flowering in rice (a short-day plant)."
Izawa T., Oikawa T., Tokutomi S., Okuno K., Shimamoto K.
Plant J. 22:391-399(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, DISRUPTION PHENOTYPE.
[7]"Analysis of PHOTOPERIOD SENSITIVITY5 sheds light on the role of phytochromes in photoperiodic flowering in rice."
Andres F., Galbraith D.W., Talon M., Domingo C.
Plant Physiol. 151:681-690(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, DISRUPTION PHENOTYPE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
EU781632 mRNA. Translation: ACE98543.1.
AP003615 Genomic DNA. Translation: BAD35463.1.
AP008212 Genomic DNA. Translation: BAF19925.1.
CM000143 Genomic DNA. Translation: EEE65978.1.
AK068856 mRNA. Translation: BAG91127.1.
AK104955 mRNA. Translation: BAG97040.1.
RefSeqNP_001058011.1. NM_001064546.1.
UniGeneOs.20352.

3D structure databases

ProteinModelPortalQ69XJ4.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ69XJ4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS06T0603000-01; OS06T0603000-01; OS06G0603000.
GeneID4341462.
KEGGosa:4341462.

Organism-specific databases

GrameneQ69XJ4.

Phylogenomic databases

eggNOGNOG308332.
HOGENOMHOG000265822.
KOK00510.
OMAGGRMIGR.
ProtClustDBCLSN2919695.

Family and domain databases

Gene3D1.20.910.10. 1 hit.
InterProIPR016053. Haem_Oase-like.
IPR016084. Haem_Oase-like_multi-hlx.
IPR016951. Haem_Oase_decyc_pln.
[Graphical view]
PfamPF01126. Heme_oxygenase. 1 hit.
[Graphical view]
PIRSFPIRSF030219. Heme_Oase_decyc_pln. 1 hit.
SUPFAMSSF48613. SSF48613. 1 hit.
ProtoNetSearch...

Entry information

Entry nameHMOX1_ORYSJ
AccessionPrimary (citable) accession number: Q69XJ4
Entry history
Integrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: September 13, 2004
Last modified: April 16, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations