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Q69VD9

- P2C57_ORYSJ

UniProt

Q69VD9 - P2C57_ORYSJ

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Protein

Probable protein phosphatase 2C 57

Gene

Os06g0597200

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi111 – 1111Manganese 1By similarity
Metal bindingi111 – 1111Manganese 2By similarity
Metal bindingi112 – 1121Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi279 – 2791Manganese 2By similarity
Metal bindingi322 – 3221Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein serine/threonine phosphatase activity Source: EnsemblPlants/Gramene

GO - Biological processi

  1. protein dephosphorylation Source: EnsemblPlants/Gramene
  2. regulation of defense response to virus Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

ReactomeiREACT_225339. Regulation of AMPK activity via LKB1.
REACT_248492. ISG15 antiviral mechanism.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 57 (EC:3.1.3.16)
Short name:
OsPP2C57
Gene namesi
Ordered Locus Names:Os06g0597200, LOC_Os06g39600
ORF Names:P0417D05.18-1, P0417D05.18-2
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 6

Organism-specific databases

GrameneiQ69VD9.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: EnsemblPlants/Gramene
  2. nucleus Source: EnsemblPlants/Gramene
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 367367Probable protein phosphatase 2C 57PRO_0000363304Add
BLAST

Proteomic databases

PaxDbiQ69VD9.

Expressioni

Gene expression databases

ExpressionAtlasiQ69VD9. baseline.

Structurei

3D structure databases

ProteinModelPortaliQ69VD9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini66 – 324259PP2C-likeAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi7 – 1711Poly-GlyAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PP2C-like domain.Curated

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233896.
InParanoidiQ69VD9.
KOiK14803.
OMAiWADIGSR.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q69VD9-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MEEHRLGGGG GGGGGGGRPP IPGAAGRKLP GLSRHASFVR SPANSTKSGT
60 70 80 90 100
EKTFENMDAV AYMPVVRSGG WADIGSRHTM EDVFICSDNL MKEFGVESFE
110 120 130 140 150
DGPSAFYGVF DGHGGKHAAD FVCSNLARFI VEDEDFPREI EKALSSAFLQ
160 170 180 190 200
TDAAFADACS VNSSLASGTT ALAALVVGRS LLVANAGDCR AVLCCRGKAI
210 220 230 240 250
EMSRDHKPSC NREKVRIEAS GGYVYDGYLN GQLNVARAIG DWHMEGMKAC
260 270 280 290 300
DGLGPLSAEP EVMIRNLTEE DEFLIIGCDG IWDVFRSQNA VDFARRKLQE
310 320 330 340 350
HNDPVTCCKE LVDEAIKRKS GDNLSVVVIC FNSRPPPVLT TPRPRVQRSI
360
SAEGLRELQS FLDSLAD
Length:367
Mass (Da):39,440
Last modified:September 13, 2004 - v1
Checksum:i0E0BDB6EDA142887
GO
Isoform 2 (identifier: Q69VD9-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-56: Missing.

Note: No experimental confirmation available.

Show »
Length:311
Mass (Da):33,914
Checksum:i496C47C4D630A387
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 5656Missing in isoform 2. 1 PublicationVSP_036275Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004236 Genomic DNA. Translation: BAD33042.1.
AP004236 Genomic DNA. Translation: BAD33043.1.
AP008212 Genomic DNA. Translation: BAF19901.1.
AK068472 mRNA. No translation available.
AK070996 mRNA. Translation: BAG92252.1.
RefSeqiNP_001057987.1. NM_001064522.1. [Q69VD9-1]
UniGeneiOs.99809.

Genome annotation databases

EnsemblPlantsiOS06T0597200-01; OS06T0597200-01; OS06G0597200. [Q69VD9-1]
GeneIDi4341433.
KEGGiosa:4341433.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004236 Genomic DNA. Translation: BAD33042.1 .
AP004236 Genomic DNA. Translation: BAD33043.1 .
AP008212 Genomic DNA. Translation: BAF19901.1 .
AK068472 mRNA. No translation available.
AK070996 mRNA. Translation: BAG92252.1 .
RefSeqi NP_001057987.1. NM_001064522.1. [Q69VD9-1 ]
UniGenei Os.99809.

3D structure databases

ProteinModelPortali Q69VD9.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PaxDbi Q69VD9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS06T0597200-01 ; OS06T0597200-01 ; OS06G0597200 . [Q69VD9-1 ]
GeneIDi 4341433.
KEGGi osa:4341433.

Organism-specific databases

Gramenei Q69VD9.

Phylogenomic databases

eggNOGi COG0631.
HOGENOMi HOG000233896.
InParanoidi Q69VD9.
KOi K14803.
OMAi WADIGSR.

Enzyme and pathway databases

Reactomei REACT_225339. Regulation of AMPK activity via LKB1.
REACT_248492. ISG15 antiviral mechanism.

Gene expression databases

ExpressionAtlasi Q69VD9. baseline.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 1 hit.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 1 hit.
PROSITEi PS01032. PP2C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  3. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    Strain: cv. Nipponbare.
  4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C57_ORYSJ
AccessioniPrimary (citable) accession number: Q69VD9
Secondary accession number(s): Q69VD8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: September 13, 2004
Last modified: November 26, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3