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Q69VD9 (P2C57_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable protein phosphatase 2C 57

Short name=OsPP2C57
EC=3.1.3.16
Gene names
Ordered Locus Names:Os06g0597200, LOC_Os06g39600
ORF Names:P0417D05.18-1, P0417D05.18-2
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length367 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity.

Sequence similarities

Belongs to the PP2C family.

Contains 1 PP2C-like domain.

Ontologies

Keywords
   Coding sequence diversityAlternative splicing
   LigandMagnesium
Manganese
Metal-binding
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processprotein dephosphorylation

Inferred from electronic annotation. Source: InterPro

regulation of defense response to virus

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Cellular_componentcytosol

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

nucleus

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

protein serine/threonine phosphatase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q69VD9-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q69VD9-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-56: Missing.
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 367367Probable protein phosphatase 2C 57
PRO_0000363304

Regions

Domain66 – 324259PP2C-like
Compositional bias7 – 1711Poly-Gly

Sites

Metal binding1111Manganese 1 By similarity
Metal binding1111Manganese 2 By similarity
Metal binding1121Manganese 1; via carbonyl oxygen By similarity
Metal binding2791Manganese 2 By similarity
Metal binding3221Manganese 2 By similarity

Natural variations

Alternative sequence1 – 5656Missing in isoform 2.
VSP_036275

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified September 13, 2004. Version 1.
Checksum: 0E0BDB6EDA142887

FASTA36739,440
        10         20         30         40         50         60 
MEEHRLGGGG GGGGGGGRPP IPGAAGRKLP GLSRHASFVR SPANSTKSGT EKTFENMDAV 

        70         80         90        100        110        120 
AYMPVVRSGG WADIGSRHTM EDVFICSDNL MKEFGVESFE DGPSAFYGVF DGHGGKHAAD 

       130        140        150        160        170        180 
FVCSNLARFI VEDEDFPREI EKALSSAFLQ TDAAFADACS VNSSLASGTT ALAALVVGRS 

       190        200        210        220        230        240 
LLVANAGDCR AVLCCRGKAI EMSRDHKPSC NREKVRIEAS GGYVYDGYLN GQLNVARAIG 

       250        260        270        280        290        300 
DWHMEGMKAC DGLGPLSAEP EVMIRNLTEE DEFLIIGCDG IWDVFRSQNA VDFARRKLQE 

       310        320        330        340        350        360 
HNDPVTCCKE LVDEAIKRKS GDNLSVVVIC FNSRPPPVLT TPRPRVQRSI SAEGLRELQS 


FLDSLAD 

« Hide

Isoform 2 [UniParc].

Checksum: 496C47C4D630A387
Show »

FASTA31133,914

References

« Hide 'large scale' references
[1]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[3]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
Strain: cv. Nipponbare.
[4]"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP004236 Genomic DNA. Translation: BAD33042.1.
AP004236 Genomic DNA. Translation: BAD33043.1.
AP008212 Genomic DNA. Translation: BAF19901.1.
AK068472 mRNA. No translation available.
AK070996 mRNA. Translation: BAG92252.1.
RefSeqNP_001057987.1. NM_001064522.1.
UniGeneOs.99809.

3D structure databases

ProteinModelPortalQ69VD9.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PaxDbQ69VD9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS06T0597200-01; OS06T0597200-01; OS06G0597200. [Q69VD9-1]
GeneID4341433.
KEGGosa:4341433.

Organism-specific databases

GrameneQ69VD9.

Phylogenomic databases

eggNOGCOG0631.
HOGENOMHOG000233896.
KOK14803.
OMAHAADFVC.
ProtClustDBPLN03145.

Family and domain databases

Gene3D3.60.40.10. 1 hit.
InterProIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERPTHR13832. PTHR13832. 1 hit.
PfamPF00481. PP2C. 1 hit.
[Graphical view]
SMARTSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. SSF81606. 1 hit.
PROSITEPS01032. PP2C. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameP2C57_ORYSJ
AccessionPrimary (citable) accession number: Q69VD9
Secondary accession number(s): Q69VD8
Entry history
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: September 13, 2004
Last modified: April 16, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations