Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable cellulose synthase A catalytic subunit 3 [UDP-forming]

Gene

CESA3

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Probable catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation.By similarity

Catalytic activityi

UDP-glucose + (1,4-beta-D-glucosyl)(n) = UDP + (1,4-beta-D-glucosyl)(n+1).

Cofactori

Zn2+By similarityNote: Binds 2 Zn2+ ions per subunit.By similarity

Pathwayi: plant cellulose biosynthesis

This protein is involved in the pathway plant cellulose biosynthesis, which is part of Glycan metabolism.
View all proteins of this organism that are known to be involved in the pathway plant cellulose biosynthesis and in Glycan metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi39Zinc 1By similarity1
Metal bindingi42Zinc 1By similarity1
Metal bindingi58Zinc 2By similarity1
Metal bindingi61Zinc 2By similarity1
Metal bindingi66Zinc 1By similarity1
Metal bindingi69Zinc 1By similarity1
Metal bindingi81Zinc 2By similarity1
Metal bindingi84Zinc 2By similarity1
Active sitei399Sequence analysis1
Binding sitei565SubstrateSequence analysis1
Binding sitei567SubstrateSequence analysis1
Active sitei793Sequence analysis1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri39 – 85RING-type; degeneratePROSITE-ProRule annotationAdd BLAST47

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processCell wall biogenesis/degradation, Cellulose biosynthesis
LigandMetal-binding, Zinc

Enzyme and pathway databases

UniPathwayiUPA00695.

Protein family/group databases

CAZyiGT2. Glycosyltransferase Family 2.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cellulose synthase A catalytic subunit 3 [UDP-forming] (EC:2.4.1.12)
Alternative name(s):
OsCesA3
Gene namesi
Name:CESA3
Ordered Locus Names:Os07g0424400, LOC_Os07g24190
ORF Names:P0409D09.11
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 280CytoplasmicSequence analysisAdd BLAST280
Transmembranei281 – 301HelicalSequence analysisAdd BLAST21
Topological domaini302 – 303ExtracellularSequence analysis2
Transmembranei304 – 324HelicalSequence analysisAdd BLAST21
Topological domaini325 – 869CytoplasmicSequence analysisAdd BLAST545
Transmembranei870 – 890HelicalSequence analysisAdd BLAST21
Topological domaini891 – 902ExtracellularSequence analysisAdd BLAST12
Transmembranei903 – 923HelicalSequence analysisAdd BLAST21
Topological domaini924 – 939CytoplasmicSequence analysisAdd BLAST16
Transmembranei940 – 960HelicalSequence analysisAdd BLAST21
Topological domaini961 – 988ExtracellularSequence analysisAdd BLAST28
Transmembranei989 – 1009HelicalSequence analysisAdd BLAST21
Topological domaini1010 – 1020CytoplasmicSequence analysisAdd BLAST11
Transmembranei1021 – 1041HelicalSequence analysisAdd BLAST21
Topological domaini1042 – 1050ExtracellularSequence analysis9
Transmembranei1051 – 1071HelicalSequence analysisAdd BLAST21
Topological domaini1072 – 1093CytoplasmicSequence analysisAdd BLAST22

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003193611 – 1093Probable cellulose synthase A catalytic subunit 3 [UDP-forming]Add BLAST1093

Proteomic databases

PaxDbiQ69V23.

Expressioni

Gene expression databases

ExpressionAtlasiQ69V23. baseline and differential.
GenevisibleiQ69V23. OS.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os07g24190.1.

Structurei

3D structure databases

ProteinModelPortaliQ69V23.
SMRiQ69V23.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili453 – 480Sequence analysisAdd BLAST28

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri39 – 85RING-type; degeneratePROSITE-ProRule annotationAdd BLAST47

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix, Zinc-finger

Phylogenomic databases

eggNOGiENOG410IER8. Eukaryota.
COG1215. LUCA.
HOGENOMiHOG000241942.
InParanoidiQ69V23.
KOiK10999.
OMAiSHPQCRI.
OrthoDBiEOG093600TW.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
3.90.550.10. 1 hit.
InterProiView protein in InterPro
IPR005150. Cellulose_synth.
IPR027934. CES_Znf_RING.
IPR029044. Nucleotide-diphossugar_trans.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
PfamiView protein in Pfam
PF03552. Cellulose_synt. 1 hit.
PF14569. zf-UDP. 1 hit.
SUPFAMiSSF53448. SSF53448. 3 hits.
PROSITEiView protein in PROSITE
PS50089. ZF_RING_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q69V23-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEASAGLVAG SHNRNELVVI RRDGDPGPKP LRQQNGQVCQ ICGDDVGLNP
60 70 80 90 100
DGEPFVACNE CAFPVCRDCY EYERREGTQN CPQCKTRFKR LRGCARVPGD
110 120 130 140 150
EEEDGVDDLE NEFNWRDRND SQYVAESMLH AHMSYGRGGV DVNGVPQPFQ
160 170 180 190 200
PNPNVPLLTD GQMVDDIPPE QHALVPSFMG GGGKRIHPLP YADPNLPVQP
210 220 230 240 250
RSMDPSKDLA AYGYGSVAWK ERMESWKQKQ ERLHQMRNDG GGKDWDGDGD
260 270 280 290 300
DGDLPLMDEA RQPLSRKVPI PSSQINPYRM VIIIRLVVLG FFFHYRVMHP
310 320 330 340 350
VPDAFALWLI SVICEIWFAM SWILDQFPKW FPIERETYLD RLTLRFDKEG
360 370 380 390 400
QTSQLAPIDF FVSTVDPLKE PPLVTANTVL SILAVDYPVD KVSCYVSDDG
410 420 430 440 450
AAMLTFEALS ETSEFAKKWV PFCKKYSIEP RAPEWYFQQK IDYLKDKVAP
460 470 480 490 500
YFVRERRAMK REYEEFKVRI NALVAKAQKV PEEGWTMQDG TPWPGNNVRD
510 520 530 540 550
HPGMIQVFLG QSGGHDIEGN ELPRLVYVSR EKRPGYNHHK KAGAMNALVR
560 570 580 590 600
VSAVLTNAPY MLNLDCDHYI NNSKAIKEAM CFMMDPLVGK KVCYVQFPQR
610 620 630 640 650
FDGIDRHDRY ANRNVVFFDI NMKGLDGIQG PIYVGTGCVF RRQALYGYDA
660 670 680 690 700
PKTKKPPSRT CNCWPKWCIC CCCFGDRKSK KKTTKPKTEK KKRSFFKRAE
710 720 730 740 750
NQSPAYALGE IEEGAPGAEN EKAGIVNQQK LEKKFGQSSV FVASTLLENG
760 770 780 790 800
GTLKSASPAS LLKEAIHVIS CGYEDKTDWG KEIGWIYGSV TEDILTGFKM
810 820 830 840 850
HCHGWRSIYC IPKLPAFKGS APLNLSDRLH QVLRWALGSV EIFFSNHCPL
860 870 880 890 900
WYGYGGGLKC LERFSYINSI VYPFTSIPLL AYCTLPAICL LTGKFITPEL
910 920 930 940 950
TNVASLWFMS LFICIFATGI LEMRWSGVGI DDWWRNEQFW VIGGVSSHLF
960 970 980 990 1000
ALFQGLLKVI AGIDTSFTVT SKGGDDEEFS ELYTFKWTTL LIPPTTLLLL
1010 1020 1030 1040 1050
NFIGVVAGVS NAINNGYESW GPLFGKLFFA FWVIVHLYPF LKGLVGRQNR
1060 1070 1080 1090
TPTIVIVWSI LLASIFSLLW VRIDPFLAKN DGPLLEECGL DCN
Length:1,093
Mass (Da):123,503
Last modified:September 13, 2004 - v1
Checksum:i33075A79C634AD31
GO

Sequence cautioni

Q69V23: The sequence AK073561 differs from that shown. Reason: Frameshift at position 499.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004298 Genomic DNA. Translation: BAD30574.1.
AP008213 Genomic DNA. Translation: BAF21401.1.
AP014963 Genomic DNA. Translation: BAT01208.1.
AK073561 mRNA. No translation available.
AK121193 mRNA. Translation: BAH00360.1.
RefSeqiXP_015646807.1. XM_015791321.1.
UniGeneiOs.10178.

Genome annotation databases

EnsemblPlantsiOS07T0424400-01; OS07T0424400-01; OS07G0424400.
OS07T0424400-06; OS07T0424400-06; OS07G0424400.
GeneIDi4343049.
GrameneiOS07T0424400-01; OS07T0424400-01; OS07G0424400.
OS07T0424400-06; OS07T0424400-06; OS07G0424400.
KEGGiosa:4343049.

Similar proteinsi

Entry informationi

Entry nameiCESA3_ORYSJ
AccessioniPrimary (citable) accession number: Q69V23
Secondary accession number(s): B7F6W2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: September 13, 2004
Last modified: August 30, 2017
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families