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Q69ST6 (PID13_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein disulfide isomerase-like 1-3

Short name=OsPDIL1-3
EC=5.3.4.1
Gene names
Name:PDIL1-3
Ordered Locus Names:Os02g0554900, LOC_Os02g34940
ORF Names:P0470G10.25
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length545 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Acts as a protein-folding catalyst that interacts with nascent polypeptides to catalyze the formation, isomerization, and reduction or oxidation of disulfide bonds. May play a role in storage protein biogenesis By similarity.

Catalytic activity

Catalyzes the rearrangement of -S-S- bonds in proteins.

Subcellular location

Endoplasmic reticulum lumen Probable.

Sequence similarities

Belongs to the protein disulfide isomerase family.

Contains 2 thioredoxin domains.

Sequence caution

The sequence BAG93318.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – ?
Chain? – 545Protein disulfide isomerase-like 1-3PRO_0000400030

Regions

Domain55 – 189135Thioredoxin 1
Domain403 – 545143Thioredoxin 2
Motif542 – 5454Prevents secretion from ER By similarity

Sites

Active site1071Nucleophile By similarity
Active site1101Nucleophile By similarity
Active site4531Nucleophile By similarity
Active site4561Nucleophile By similarity
Site1081Contributes to redox potential value By similarity
Site1091Contributes to redox potential value By similarity
Site1751Lowers pKa of C-terminal Cys of first active site By similarity
Site4541Contributes to redox potential value By similarity
Site4551Contributes to redox potential value By similarity
Site5151Lowers pKa of C-terminal Cys of second active site By similarity

Amino acid modifications

Glycosylation871N-linked (GlcNAc...) Potential
Glycosylation3491N-linked (GlcNAc...) Potential
Disulfide bond107 ↔ 110Redox-active By similarity
Disulfide bond453 ↔ 456Redox-active By similarity

Sequences

Sequence LengthMass (Da)Tools
Q69ST6 [UniParc].

Last modified October 25, 2004. Version 1.
Checksum: 362611FD2AD09ED1

FASTA54559,075
        10         20         30         40         50         60 
MWPRAPATPP PPPWPSKPSA ASRSALRRLD LDDGRRQGTE GEENHAPLLC SPAMASSTAF 

        70         80         90        100        110        120 
AAAFALLLLA SSAAAEGEAV LTLDAGNFTE VVGAHDFIVV EFYAPWCGHC NQLAPEYEAA 

       130        140        150        160        170        180 
AAALRSHDPP VVLAKVDASA DLNRGLAGEH GVQGYPTIRI LRDRGARSHN YAGPRDAAGI 

       190        200        210        220        230        240 
VAYLKRQAGP ASVEIAASAS PPAADSIAND GVVVVGVFPE LSGSEFESFM AVAEKMRADY 

       250        260        270        280        290        300 
DFRHTTDAGV LPRGDRTVRG PLVRLFKPFD ELFVDSQDFD RDALEKFIES SGFPTVVTFD 

       310        320        330        340        350        360 
TSPANQKYLL KYFDNAGTKA MLFLSFSDDR AEEFRTQFHE AANQYSANNI SFLIGDVTAS 

       370        380        390        400        410        420 
QGAFQYFGLK ESEVPLVFIL ASKSKYIKPT VEPDQILPYL KEFTEGTLAP HVKSEPIPEV 

       430        440        450        460        470        480 
NDQPVKTVVA DNLREVVFNS GKNVLLEFYA PWCGHCQKLA PILEEVAVSL KDDEDVVIAK 

       490        500        510        520        530        540 
MDGTANDVPS DFAVEGYPSM YFYSSGGNLL PYDGRTAEEI IDFITKNKGS RPGEATTTES 


VKDEL 

« Hide

References

« Hide 'large scale' references
[1]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[3]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 27-545.
Strain: cv. Nipponbare.
[4]"Phylogenetic analyses identify 10 classes of the protein disulfide isomerase family in plants, including single-domain protein disulfide isomerase-related proteins."
Houston N.L., Fan C., Xiang J.Q., Schulze J.M., Jung R., Boston R.S.
Plant Physiol. 137:762-778(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
[5]"The protein disulfide isomerase gene family in bread wheat (T. aestivum L.)."
d'Aloisio E., Paolacci A.R., Dhanapal A.P., Tanzarella O.A., Porceddu E., Ciaffi M.
BMC Plant Biol. 10:101-101(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP004876 Genomic DNA. Translation: BAD33310.1.
AP008208 Genomic DNA. Translation: BAF09033.1.
AK073161 mRNA. Translation: BAG93318.1. Different initiation.
RefSeqNP_001047119.1. NM_001053654.1.
UniGeneOs.53357.

3D structure databases

ProteinModelPortalQ69ST6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING39947.LOC_Os02g34940.1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS02T0554900-01; OS02T0554900-01; OS02G0554900.
GeneID4329652.
KEGGosa:4329652.

Organism-specific databases

GrameneQ69ST6.

Phylogenomic databases

eggNOGCOG0526.
HOGENOMHOG000162459.
KOK09580.
OMAQYSANNI.

Family and domain databases

Gene3D3.40.30.10. 3 hits.
InterProIPR005792. Prot_disulphide_isomerase.
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
IPR013766. Thioredoxin_domain.
[Graphical view]
PfamPF00085. Thioredoxin. 2 hits.
[Graphical view]
SUPFAMSSF52833. SSF52833. 4 hits.
TIGRFAMsTIGR01130. ER_PDI_fam. 1 hit.
PROSITEPS00014. ER_TARGET. 1 hit.
PS00194. THIOREDOXIN_1. 2 hits.
PS51352. THIOREDOXIN_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePID13_ORYSJ
AccessionPrimary (citable) accession number: Q69ST6
Secondary accession number(s): B7ELS1
Entry history
Integrated into UniProtKB/Swiss-Prot: November 2, 2010
Last sequence update: October 25, 2004
Last modified: June 11, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations