SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q69ST6

- PID13_ORYSJ

UniProt

Q69ST6 - PID13_ORYSJ

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Protein disulfide isomerase-like 1-3

Gene
PDIL1-3, Os02g0554900, LOC_Os02g34940, P0470G10.25
Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Acts as a protein-folding catalyst that interacts with nascent polypeptides to catalyze the formation, isomerization, and reduction or oxidation of disulfide bonds. May play a role in storage protein biogenesis By similarity.

Catalytic activityi

Catalyzes the rearrangement of -S-S- bonds in proteins.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei107 – 1071Nucleophile By similarity
Sitei108 – 1081Contributes to redox potential value By similarity
Sitei109 – 1091Contributes to redox potential value By similarity
Active sitei110 – 1101Nucleophile By similarity
Sitei175 – 1751Lowers pKa of C-terminal Cys of first active site By similarity
Active sitei453 – 4531Nucleophile By similarity
Sitei454 – 4541Contributes to redox potential value By similarity
Sitei455 – 4551Contributes to redox potential value By similarity
Active sitei456 – 4561Nucleophile By similarity
Sitei515 – 5151Lowers pKa of C-terminal Cys of second active site By similarity

GO - Molecular functioni

  1. protein disulfide isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. cell redox homeostasis Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Names & Taxonomyi

Protein namesi
Recommended name:
Protein disulfide isomerase-like 1-3 (EC:5.3.4.1)
Short name:
OsPDIL1-3
Gene namesi
Name:PDIL1-3
Ordered Locus Names:Os02g0554900, LOC_Os02g34940
ORF Names:P0470G10.25
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 2

Organism-specific databases

GrameneiQ69ST6.

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum lumen Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini? – 545Protein disulfide isomerase-like 1-3PRO_0000400030
Signal peptidei1 – ?

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi87 – 871N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi107 ↔ 110Redox-active By similarity
Glycosylationi349 – 3491N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi453 ↔ 456Redox-active By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os02g34940.1.

Structurei

3D structure databases

ProteinModelPortaliQ69ST6.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini55 – 189135Thioredoxin 1Add
BLAST
Domaini403 – 545143Thioredoxin 2Add
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi542 – 5454Prevents secretion from ER By similarity

Sequence similaritiesi

Contains 2 thioredoxin domains.

Keywords - Domaini

Redox-active center, Repeat, Signal

Phylogenomic databases

eggNOGiCOG0526.
HOGENOMiHOG000162459.
KOiK09580.
OMAiQYSANNI.

Family and domain databases

Gene3Di3.40.30.10. 3 hits.
InterProiIPR005792. Prot_disulphide_isomerase.
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
IPR013766. Thioredoxin_domain.
[Graphical view]
PfamiPF00085. Thioredoxin. 2 hits.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 4 hits.
TIGRFAMsiTIGR01130. ER_PDI_fam. 1 hit.
PROSITEiPS00014. ER_TARGET. 1 hit.
PS00194. THIOREDOXIN_1. 2 hits.
PS51352. THIOREDOXIN_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q69ST6-1 [UniParc]FASTAAdd to Basket

« Hide

MWPRAPATPP PPPWPSKPSA ASRSALRRLD LDDGRRQGTE GEENHAPLLC    50
SPAMASSTAF AAAFALLLLA SSAAAEGEAV LTLDAGNFTE VVGAHDFIVV 100
EFYAPWCGHC NQLAPEYEAA AAALRSHDPP VVLAKVDASA DLNRGLAGEH 150
GVQGYPTIRI LRDRGARSHN YAGPRDAAGI VAYLKRQAGP ASVEIAASAS 200
PPAADSIAND GVVVVGVFPE LSGSEFESFM AVAEKMRADY DFRHTTDAGV 250
LPRGDRTVRG PLVRLFKPFD ELFVDSQDFD RDALEKFIES SGFPTVVTFD 300
TSPANQKYLL KYFDNAGTKA MLFLSFSDDR AEEFRTQFHE AANQYSANNI 350
SFLIGDVTAS QGAFQYFGLK ESEVPLVFIL ASKSKYIKPT VEPDQILPYL 400
KEFTEGTLAP HVKSEPIPEV NDQPVKTVVA DNLREVVFNS GKNVLLEFYA 450
PWCGHCQKLA PILEEVAVSL KDDEDVVIAK MDGTANDVPS DFAVEGYPSM 500
YFYSSGGNLL PYDGRTAEEI IDFITKNKGS RPGEATTTES VKDEL 545
Length:545
Mass (Da):59,075
Last modified:October 25, 2004 - v1
Checksum:i362611FD2AD09ED1
GO

Sequence cautioni

The sequence BAG93318.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP004876 Genomic DNA. Translation: BAD33310.1.
AP008208 Genomic DNA. Translation: BAF09033.1.
AK073161 mRNA. Translation: BAG93318.1. Different initiation.
RefSeqiNP_001047119.1. NM_001053654.1.
UniGeneiOs.53357.

Genome annotation databases

EnsemblPlantsiOS02T0554900-01; OS02T0554900-01; OS02G0554900.
GeneIDi4329652.
KEGGiosa:4329652.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP004876 Genomic DNA. Translation: BAD33310.1 .
AP008208 Genomic DNA. Translation: BAF09033.1 .
AK073161 mRNA. Translation: BAG93318.1 . Different initiation.
RefSeqi NP_001047119.1. NM_001053654.1.
UniGenei Os.53357.

3D structure databases

ProteinModelPortali Q69ST6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 39947.LOC_Os02g34940.1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS02T0554900-01 ; OS02T0554900-01 ; OS02G0554900 .
GeneIDi 4329652.
KEGGi osa:4329652.

Organism-specific databases

Gramenei Q69ST6.

Phylogenomic databases

eggNOGi COG0526.
HOGENOMi HOG000162459.
KOi K09580.
OMAi QYSANNI.

Family and domain databases

Gene3Di 3.40.30.10. 3 hits.
InterProi IPR005792. Prot_disulphide_isomerase.
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
IPR013766. Thioredoxin_domain.
[Graphical view ]
Pfami PF00085. Thioredoxin. 2 hits.
[Graphical view ]
SUPFAMi SSF52833. SSF52833. 4 hits.
TIGRFAMsi TIGR01130. ER_PDI_fam. 1 hit.
PROSITEi PS00014. ER_TARGET. 1 hit.
PS00194. THIOREDOXIN_1. 2 hits.
PS51352. THIOREDOXIN_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  3. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 27-545.
    Strain: cv. Nipponbare.
  4. "Phylogenetic analyses identify 10 classes of the protein disulfide isomerase family in plants, including single-domain protein disulfide isomerase-related proteins."
    Houston N.L., Fan C., Xiang J.Q., Schulze J.M., Jung R., Boston R.S.
    Plant Physiol. 137:762-778(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.
  5. "The protein disulfide isomerase gene family in bread wheat (T. aestivum L.)."
    d'Aloisio E., Paolacci A.R., Dhanapal A.P., Tanzarella O.A., Porceddu E., Ciaffi M.
    BMC Plant Biol. 10:101-101(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiPID13_ORYSJ
AccessioniPrimary (citable) accession number: Q69ST6
Secondary accession number(s): B7ELS1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 2, 2010
Last sequence update: October 25, 2004
Last modified: September 3, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi