Reviewed, UniProtKB/Swiss-Prot Q69RG7 (4CLL7_ORYSJ)

Names and origin

Protein names

Recommended name:
    4-coumarate--CoA ligase-like 7
    EC=6.2.1.-

Gene names

Name:	4CLL7
Ordered Locus Names:	Os07g0280200, LOC_Os07g17970
ORF Names:	P0474B11.33

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	558 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Domain	Both substrate-binding domains (SBD1 and SBD2) are involved in the substrate recognition, and are sufficient to confer the substrate specificity.
Sequence similarities	Belongs to the ATP-dependent AMP-binding enzyme family.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Ligase
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ligase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 558	558	4-coumarate--CoA ligase-like 7		PRO_0000351633
Regions
	Nucleotide binding	212 – 220	9	ATP By similarity
	Nucleotide binding	350 – 355	6	ATP By similarity
	Region	284 – 349	66	SBD1
	Region	350 – 413	64	SBD2
	Compositional bias	55 – 62	8	Poly-Ser
Sites
	Binding site	434	1	ATP By similarity
	Binding site	449	1	ATP By similarity
	Binding site	540	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q69RG7-1 [UniParc]. Last modified September 13, 2004. Version 1. Checksum: B2D55391D2FFC50D	FASTA	558	59,318
	10 20 30 40 50 60 MAAPTSMANA DGESTRTGYC AATKSFRSLR PPVPLPPPDV PLSFPEFAFS LLPRSSSSSS 70 80 90 100 110 120 SSLLPANPAL VDAATGEAVS FQAFLSRVRA LAGALRSRVG LRGGDVAFVL APAGLDVPVL 130 140 150 160 170 180 YFALLSIGAV VSPANPALTP AEVSRLVSLS GASVAFAVSS TATKLPAGLT TVVLLDSPHF 190 200 210 220 230 240 RSLLMDCGQA QGQEPLPVVV VRQSETAAIQ YSSGTTGRVK AAALPHRSFI AMVAGFHALR 250 260 270 280 290 300 AKAREVRTLL GAPMFHSMGF LFVLQGVALG ATTVVVTDAV ARAGIRGLVE AAERWAVMDM 310 320 330 340 350 360 TASPPVVLGM TKQRCRLPAL ERITCGGAPL PAPAIERFRR RFPHVDLCMG YGSTEAGGIS 370 380 390 400 410 420 RMISQEECNH IGSAGRVTEN VEVKIVDHVT GKPLPAGQQG ELWVRGPAVM TGYVGDNEAN 430 440 450 460 470 480 ATTFNSEGWL KTGDLCYIDQ DGFLFVVDRL KELIKYKAYQ VPPAELELVL HSLPQIVDAA 490 500 510 520 530 540 VMPYPHEEAG QIPVALVVKQ PGSKLTEAEV MYNVAKQVAP YKKIRKVLFV DSIPKSPSGK 550 ILRRELVNHL RLCELSRL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed: 16100779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"Curated genome annotation of Oryza sativa ssp. japonica and comparative genome analysis with Arabidopsis thaliana." The rice annotation project (RAP) Genome Res. 17:175-183(2007) [PubMed: 17210932] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[3]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed: 12869764] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.
[4]	"Genome-wide analysis of a land plant-specific acyl:coenzyme A synthetase (ACS) gene family in Arabidopsis, poplar, rice and Physcomitrella." de Azevedo Souza C., Barbazuk B., Ralph S.G., Bohlmann J., Hamberger B., Douglas C.J. New Phytol. 179:987-1003(2008) [PubMed: 18627494] [Abstract] Cited for: GENE FAMILY.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP005189 Genomic DNA. Translation: BAD31128.1. AP008213 Genomic DNA. Translation: BAF21287.1. AK108656 mRNA. No translation available.
RefSeq	NP_001059373.1.
UniGene	Os.15398
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4342925.
KEGG	osa:4342925.
Organism-specific databases
Gramene	Q69RG7.
Family and domain databases
InterPro	IPR000873. AMP-dep_Synth/Lig. [Graphical view]
Pfam	PF00501. AMP-binding. 1 hit. [Graphical view]
PROSITE	PS00455. AMP_BINDING. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

4CLL7_ORYSJ

Accession

Primary (citable) accession number: Q69RG7

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 14, 2008
Last sequence update:	September 13, 2004
Last modified:	March 24, 2009
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)