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Protein

Laccase-14

Gene

LAC14

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Cu cationBy similarityNote: Binds 4 Cu cations per monomer.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi88Copper 1By similarity1
Metal bindingi90Copper 2By similarity1
Metal bindingi137Copper 2By similarity1
Metal bindingi139Copper 3By similarity1
Metal bindingi482Copper 4By similarity1
Metal bindingi485Copper 1By similarity1
Metal bindingi487Copper 3By similarity1
Metal bindingi546Copper 3By similarity1
Metal bindingi547Copper 4By similarity1
Metal bindingi548Copper 2By similarity1
Metal bindingi552Copper 4By similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Lignin degradation

Keywords - Ligandi

Copper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-14 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 14
Diphenol oxidase 14
Urishiol oxidase 14
Gene namesi
Name:LAC14
Ordered Locus Names:Os07g0101000, LOC_Os07g01110
ORF Names:B1026C12.14, OsJ_021873
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 7

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30Sequence analysisAdd BLAST30
ChainiPRO_000029189831 – 583Laccase-14Add BLAST553

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi41N-linked (GlcNAc...)Sequence analysis1
Glycosylationi84N-linked (GlcNAc...)Sequence analysis1
Glycosylationi126N-linked (GlcNAc...)Sequence analysis1
Glycosylationi179N-linked (GlcNAc...)Sequence analysis1
Glycosylationi251N-linked (GlcNAc...)Sequence analysis1
Glycosylationi304N-linked (GlcNAc...)Sequence analysis1
Glycosylationi338N-linked (GlcNAc...)Sequence analysis1
Glycosylationi388N-linked (GlcNAc...)Sequence analysis1
Glycosylationi400N-linked (GlcNAc...)Sequence analysis1
Glycosylationi446N-linked (GlcNAc...)Sequence analysis1
Glycosylationi464N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ69L99.

Expressioni

Gene expression databases

GenevisibleiQ69L99. OS.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os07g01110.1.

Structurei

3D structure databases

ProteinModelPortaliQ69L99.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini38 – 158Plastocyanin-like 1Add BLAST121
Domaini168 – 320Plastocyanin-like 2Add BLAST153
Domaini426 – 567Plastocyanin-like 3Add BLAST142

Sequence similaritiesi

Belongs to the multicopper oxidase family.Curated
Contains 3 plastocyanin-like domains.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiKOG1263. Eukaryota.
COG2132. LUCA.
HOGENOMiHOG000241916.
InParanoidiQ69L99.
OMAiKTIIMSP.
OrthoDBiEOG093605LR.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 4 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q69L99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPSLGSGST RILLIVSLLL CLRQQAVVDA AIVEHTFHVG NLTVERLGQR
60 70 80 90 100
QVITAVNGQF PGPKVEARNG DTLLVRVVNN SPYNITIHWH GVLQRLSAWA
110 120 130 140 150
DGPAMVTQCP ILPGSGAGSS YTYRFNVTGQ EGTLWWHAHV SFLRATVYGA
160 170 180 190 200
LLIRPRPGVP YPFPAPHAEH TLLLGEWWNA SATLVDVERQ AFLTGGQPAN
210 220 230 240 250
SVALTINGMP GLSHAHKEMH HLRVARGNTY LLRLVNAALN YQLFFKVAAH
260 270 280 290 300
NFTVVAVDAC YTDPYHTDVI VIAPGQTVDA LMHAGAAPGR RYYVAAQVYQ
310 320 330 340 350
SIANATYSAT ARALLRYDDD AKDAAKTIIM SPRMPVLNDS ATAQRFYGSL
360 370 380 390 400
TGLLRDGKPT VPQRVDTRMV VTYGLAIAPC LPAQTLCNRT RGSLAASMNN
410 420 430 440 450
VSFQLPATMS LLEASRSRSS GVYTRDFPDR PPVMFDFTNA AAVNRNMSLM
460 470 480 490 500
VTSKGTRVKA LRYNETVEVV LQNTAVLGTE NHPLHLHGFN FYVLAQGTGN
510 520 530 540 550
YYYLIRKKKI RKNLVNPQQR NTIAVPPGGW AVIRFTADNP GVWLMHCHLE
560 570 580
AHLPFGLAMA FDVQDGPTPD AMLPPPPNDY PPC
Length:583
Mass (Da):63,802
Last modified:October 25, 2004 - v1
Checksum:i68AFA7E109F0A882
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP005869 Genomic DNA. Translation: BAD31823.1.
AP008213 Genomic DNA. Translation: BAH93742.1.
AP014963 Genomic DNA. Translation: BAS99676.1.
CM000144 Genomic DNA. No translation available.
RefSeqiXP_015647729.1. XM_015792243.1.

Genome annotation databases

EnsemblPlantsiOS07T0101000-00; OS07T0101000-00; OS07G0101000.
GeneIDi9272497.
GrameneiOS07T0101000-00; OS07T0101000-00; OS07G0101000.
KEGGiosa:9272497.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP005869 Genomic DNA. Translation: BAD31823.1.
AP008213 Genomic DNA. Translation: BAH93742.1.
AP014963 Genomic DNA. Translation: BAS99676.1.
CM000144 Genomic DNA. No translation available.
RefSeqiXP_015647729.1. XM_015792243.1.

3D structure databases

ProteinModelPortaliQ69L99.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os07g01110.1.

Proteomic databases

PaxDbiQ69L99.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS07T0101000-00; OS07T0101000-00; OS07G0101000.
GeneIDi9272497.
GrameneiOS07T0101000-00; OS07T0101000-00; OS07G0101000.
KEGGiosa:9272497.

Phylogenomic databases

eggNOGiKOG1263. Eukaryota.
COG2132. LUCA.
HOGENOMiHOG000241916.
InParanoidiQ69L99.
OMAiKTIIMSP.
OrthoDBiEOG093605LR.

Gene expression databases

GenevisibleiQ69L99. OS.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 4 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLAC14_ORYSJ
AccessioniPrimary (citable) accession number: Q69L99
Secondary accession number(s): C7J548
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: October 25, 2004
Last modified: November 30, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.