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Protein

Laccase-14

Gene

LAC14

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Cu cationBy similarityNote: Binds 4 Cu cations per monomer.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi88 – 881Copper 1By similarity
Metal bindingi90 – 901Copper 2By similarity
Metal bindingi137 – 1371Copper 2By similarity
Metal bindingi139 – 1391Copper 3By similarity
Metal bindingi482 – 4821Copper 4By similarity
Metal bindingi485 – 4851Copper 1By similarity
Metal bindingi487 – 4871Copper 3By similarity
Metal bindingi546 – 5461Copper 3By similarity
Metal bindingi547 – 5471Copper 4By similarity
Metal bindingi548 – 5481Copper 2By similarity
Metal bindingi552 – 5521Copper 4By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Lignin degradation

Keywords - Ligandi

Copper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-14 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 14
Diphenol oxidase 14
Urishiol oxidase 14
Gene namesi
Name:LAC14
Ordered Locus Names:Os07g0101000, LOC_Os07g01110
ORF Names:B1026C12.14, OsJ_021873
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
ProteomesiUP000000763 Componenti: Chromosome 7

Organism-specific databases

GrameneiQ69L99.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3030Sequence AnalysisAdd
BLAST
Chaini31 – 583553Laccase-14PRO_0000291898Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi41 – 411N-linked (GlcNAc...)Sequence Analysis
Glycosylationi84 – 841N-linked (GlcNAc...)Sequence Analysis
Glycosylationi126 – 1261N-linked (GlcNAc...)Sequence Analysis
Glycosylationi179 – 1791N-linked (GlcNAc...)Sequence Analysis
Glycosylationi251 – 2511N-linked (GlcNAc...)Sequence Analysis
Glycosylationi304 – 3041N-linked (GlcNAc...)Sequence Analysis
Glycosylationi338 – 3381N-linked (GlcNAc...)Sequence Analysis
Glycosylationi388 – 3881N-linked (GlcNAc...)Sequence Analysis
Glycosylationi400 – 4001N-linked (GlcNAc...)Sequence Analysis
Glycosylationi446 – 4461N-linked (GlcNAc...)Sequence Analysis
Glycosylationi464 – 4641N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Expressioni

Gene expression databases

ExpressionAtlasiQ69L99. baseline.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os07g01110.1.

Structurei

3D structure databases

ProteinModelPortaliQ69L99.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini38 – 158121Plastocyanin-like 1Add
BLAST
Domaini168 – 320153Plastocyanin-like 2Add
BLAST
Domaini426 – 567142Plastocyanin-like 3Add
BLAST

Sequence similaritiesi

Belongs to the multicopper oxidase family.Curated
Contains 3 plastocyanin-like domains.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiCOG2132.
HOGENOMiHOG000241916.
InParanoidiQ69L99.
OMAiPAQTLCN.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 4 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q69L99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPSLGSGST RILLIVSLLL CLRQQAVVDA AIVEHTFHVG NLTVERLGQR
60 70 80 90 100
QVITAVNGQF PGPKVEARNG DTLLVRVVNN SPYNITIHWH GVLQRLSAWA
110 120 130 140 150
DGPAMVTQCP ILPGSGAGSS YTYRFNVTGQ EGTLWWHAHV SFLRATVYGA
160 170 180 190 200
LLIRPRPGVP YPFPAPHAEH TLLLGEWWNA SATLVDVERQ AFLTGGQPAN
210 220 230 240 250
SVALTINGMP GLSHAHKEMH HLRVARGNTY LLRLVNAALN YQLFFKVAAH
260 270 280 290 300
NFTVVAVDAC YTDPYHTDVI VIAPGQTVDA LMHAGAAPGR RYYVAAQVYQ
310 320 330 340 350
SIANATYSAT ARALLRYDDD AKDAAKTIIM SPRMPVLNDS ATAQRFYGSL
360 370 380 390 400
TGLLRDGKPT VPQRVDTRMV VTYGLAIAPC LPAQTLCNRT RGSLAASMNN
410 420 430 440 450
VSFQLPATMS LLEASRSRSS GVYTRDFPDR PPVMFDFTNA AAVNRNMSLM
460 470 480 490 500
VTSKGTRVKA LRYNETVEVV LQNTAVLGTE NHPLHLHGFN FYVLAQGTGN
510 520 530 540 550
YYYLIRKKKI RKNLVNPQQR NTIAVPPGGW AVIRFTADNP GVWLMHCHLE
560 570 580
AHLPFGLAMA FDVQDGPTPD AMLPPPPNDY PPC
Length:583
Mass (Da):63,802
Last modified:October 25, 2004 - v1
Checksum:i68AFA7E109F0A882
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP005869 Genomic DNA. Translation: BAD31823.1.
CM000144 Genomic DNA. No translation available.
RefSeqiNP_001175014.1. NM_001188085.1.
UniGeneiOs.98837.

Genome annotation databases

EnsemblPlantsiOS07T0101000-00; OS07T0101000-00; OS07G0101000.
GeneIDi9272497.
KEGGiosa:9272497.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP005869 Genomic DNA. Translation: BAD31823.1.
CM000144 Genomic DNA. No translation available.
RefSeqiNP_001175014.1. NM_001188085.1.
UniGeneiOs.98837.

3D structure databases

ProteinModelPortaliQ69L99.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os07g01110.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS07T0101000-00; OS07T0101000-00; OS07G0101000.
GeneIDi9272497.
KEGGiosa:9272497.

Organism-specific databases

GrameneiQ69L99.

Phylogenomic databases

eggNOGiCOG2132.
HOGENOMiHOG000241916.
InParanoidiQ69L99.
OMAiPAQTLCN.

Gene expression databases

ExpressionAtlasiQ69L99. baseline.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 4 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. "The genomes of Oryza sativa: a history of duplications."
    Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
    , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
    PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiLAC14_ORYSJ
AccessioniPrimary (citable) accession number: Q69L99
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: October 25, 2004
Last modified: June 24, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.