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Q68Y08 (HTPG_RICTY) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chaperone protein HtpG
Alternative name(s):
Heat shock protein HtpG
High temperature protein G
Gene names
Name:htpG
Ordered Locus Names:RT0828
OrganismRickettsia typhi (strain ATCC VR-144 / Wilmington) [Complete proteome] [HAMAP]
Taxonomic identifier257363 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group

Protein attributes

Sequence length621 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Molecular chaperone. Has ATPase activity By similarity. HAMAP-Rule MF_00505

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00505

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00505.

Sequence similarities

Belongs to the heat shock protein 90 family.

Ontologies

Keywords
   Biological processStress response
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionChaperone
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processprotein folding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

response to stress

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 621621Chaperone protein HtpG HAMAP-Rule MF_00505
PRO_0000224228

Regions

Region1 – 328328A; substrate-binding By similarity
Region329 – 544216B By similarity
Region545 – 62177C By similarity

Sequences

Sequence LengthMass (Da)Tools
Q68Y08 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: FC334AD04A502ECB

FASTA62170,937
        10         20         30         40         50         60 
MTQEKKKFDA EVGKILNLMI HSLYSNKEIF MRELISNASD ACDKLRYLSQ SNSELISGDS 

        70         80         90        100        110        120 
NFKIIVKVDK DNEQIIIRDN GIGMNKEDLI ENLGTIARSG TANFLKNLSG DSKKDNMLIG 

       130        140        150        160        170        180 
QFGVGFYSSF MVADKVTVTS RKAGENKVYT WESDGLGEYI VADSEQEFAR GTEIVLYIKK 

       190        200        210        220        230        240 
AETTFLDHFR LKHIVKSYSD HIAVPIYFCD EASNNEIQLN SASALWTRPK SEITEEQYKE 

       250        260        270        280        290        300 
FYKSLSYSVD DPWVTLHNKN EGAIEFTNLL FIPSSKTFDL FHPDRKRRVK LYIKRVFISD 

       310        320        330        340        350        360 
ENIDLIPSYL RFLRGVVDSE DLPLNISRES LQHNNVLEKI KNAITKRVLG ELRKKKEELP 

       370        380        390        400        410        420 
EEYNKFWTNF GGALKEGLCE ATTDHEKLLE VCIFRSALHN KMISIDEYIA NFKEGQNTIY 

       430        440        450        460        470        480 
YLSGDNPDKL LSSPQIEGLL NKNIDVLLFT DTVDDFWVNV NSEYKGYAIK SATRSDIDVE 

       490        500        510        520        530        540 
HTTSRPQDKN TDSKKSDDEY KLLTDYFKEI LGELVKEVKI SKKLTLSPAC LAVSDTAMDI 

       550        560        570        580        590        600 
RMERFLIEQK QIASASAKNL ELNPKNKIIE KIFNDLKANN KNNEELVNLI FDQACILEGE 

       610        620 
PIADTGAFSK RLNDILQKAI L 

« Hide

References

[1]"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae."
McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. expand/collapse author list , Hong C., Yu X.-J., Walker D.H., Weinstock G.M.
J. Bacteriol. 186:5842-5855(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017197 Genomic DNA. Translation: AAU04282.1.
RefSeqYP_067764.1. NC_006142.1.

3D structure databases

ProteinModelPortalQ68Y08.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING257363.RT0828.

Proteomic databases

PRIDEQ68Y08.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAU04282; AAU04282; RT0828.
GeneID2959007.
KEGGrty:RT0828.
PATRIC17910908. VBIRicTyp34752_0845.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0326.
HOGENOMHOG000031989.
KOK04079.
OMALTDSPAC.
OrthoDBEOG65TRNM.
ProtClustDBPRK05218.

Enzyme and pathway databases

BioCycRTYP257363:GJEQ-868-MONOMER.

Family and domain databases

Gene3D3.30.565.10. 1 hit.
HAMAPMF_00505. HSP90.
InterProIPR003594. HATPase_ATP-bd.
IPR019805. Heat_shock_protein_90_CS.
IPR001404. Hsp90_fam.
IPR020575. Hsp90_N.
IPR027058. HtpG.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
PANTHERPTHR11528. PTHR11528. 1 hit.
PTHR11528:SF39. PTHR11528:SF39. 1 hit.
PfamPF00183. HSP90. 1 hit.
[Graphical view]
PIRSFPIRSF002583. Hsp90. 1 hit.
PRINTSPR00775. HEATSHOCK90.
SMARTSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMSSF54211. SSF54211. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEPS00298. HSP90. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHTPG_RICTY
AccessionPrimary (citable) accession number: Q68Y08
Entry history
Integrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: October 11, 2004
Last modified: February 19, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia typhi

Rickettsia typhi (strain Wilmington): entries and gene names