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Q68XZ5 (FABZ_RICTY) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase

Short name=(3R)-hydroxymyristoyl ACP dehydrase
EC=4.2.1.-
Gene names
Name:fabZ
Ordered Locus Names:RT0007
OrganismRickettsia typhi (strain ATCC VR-144 / Wilmington) [Complete proteome] [HAMAP]
Taxonomic identifier257363 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group

Protein attributes

Sequence length145 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in saturated fatty acids biosynthesis. HAMAP MF_00406

Subcellular location

Cytoplasm By similarity HAMAP MF_00406.

Sequence similarities

Belongs to the thioester dehydratase family. FabZ subfamily.

Ontologies

Keywords
   Biological processLipid A biosynthesis
Lipid synthesis
   Cellular componentCytoplasm
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processfatty acid biosynthetic process

Inferred from electronic annotation. Source: InterPro

lipid A biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionhydro-lyase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 145145(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase HAMAP MF_00406
PRO_0000091723

Sites

Active site491 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q68XZ5 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 846D631057D61E89

FASTA14516,442
        10         20         30         40         50         60 
MIIAITEIMD LIPHRYPFLL VDRVLKIDPN KSITGIKNVT VNEPQFTGHF PTRPVMPGVL 

        70         80         90        100        110        120 
MVESMAQLAA ILVAKSLDST KNKEVFLMSI ENTKFRRIVQ PGDTMHIHSV IDQQRANVWK 

       130        140 
FSSKVMVECE IAAESKFTAM IKDKM 

« Hide

References

[1]"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae."
McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. expand/collapse author list , Hong C., Yu X.-J., Walker D.H., Weinstock G.M.
J. Bacteriol. 186:5842-5855(2004) [PubMed: 15317790] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017197 Genomic DNA. Translation: AAU03497.1.
RefSeqYP_066979.1. NC_006142.1.

3D structure databases

ProteinModelPortalQ68XZ5.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2959199.
GenomeReviewsGene locus RT0007 in contig AE017197_GR.
KEGGrty:RT0007.
PATRIC17909164. VBIRicTyp34752_0007.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG433282.
OMAKKQVTPG.
ProtClustDBPRK00006.

Enzyme and pathway databases

BioCycRTYP257363:RT0007-MONOMER.

Family and domain databases

HAMAPMF_00406. FabZ.
[Tree]
InterProIPR013114. FabA_FabZ.
IPR010084. FabZ.
[Graphical view]
KOK02372.
PfamPF07977. FabA. 1 hit.
[Graphical view]
TIGRFAMsTIGR01750. FabZ. 1 hit.
ProtoNetSearch...

Entry information

Entry nameFABZ_RICTY
AccessionPrimary (citable) accession number: Q68XZ5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: October 11, 2004
Last modified: January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Rickettsia typhi

Rickettsia typhi (strain Wilmington): entries and gene names

SIMILARITY comments

Index of protein domains and families