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Q68XZ3

- DUS_RICTY

UniProt

Q68XZ3 - DUS_RICTY

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Protein

Probable tRNA-dihydrouridine synthase

Gene
dus, RT0010
Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs By similarity.

Cofactori

FAD By similarity.

GO - Molecular functioni

  1. flavin adenine dinucleotide binding Source: InterPro
  2. tRNA dihydrouridine synthase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

BioCyciRTYP257363:GJEQ-10-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable tRNA-dihydrouridine synthase (EC:1.-.-.-)
Gene namesi
Name:dus
Ordered Locus Names:RT0010
OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
Taxonomic identifieri257363 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000000604: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 327327Probable tRNA-dihydrouridine synthasePRO_0000280961Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi257363.RT0010.

Structurei

3D structure databases

ProteinModelPortaliQ68XZ3.

Family & Domainsi

Sequence similaritiesi

Belongs to the Dus family.

Phylogenomic databases

eggNOGiCOG0042.
HOGENOMiHOG000217855.
OMAiRYQKDKI.
OrthoDBiEOG6VHZFQ.

Family and domain databases

Gene3Di1.10.1200.80. 1 hit.
3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR024036. tRNA-dHydroUridine_Synthase_C.
IPR004652. tRNA_dU_NifR3.
IPR001269. tRNA_hU_synthase.
IPR018517. tRNA_hU_synthase_CS.
[Graphical view]
PANTHERiPTHR11082. PTHR11082. 1 hit.
PfamiPF01207. Dus. 1 hit.
[Graphical view]
PIRSFiPIRSF006621. Dus. 1 hit.
TIGRFAMsiTIGR00737. nifR3_yhdG. 1 hit.
PROSITEiPS01136. UPF0034. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q68XZ3-1 [UniParc]FASTAAdd to Basket

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MIKIGNIELS SNVILAPMSN ITDLEFRKLV KRFGAGLVVS EMIASRAMIM    50
KSRQSMQKCA IMHDDPTSAC VQLAGCEPDV IADAAKMNED MGAKIIDLNF 100
GCPAKKVVGG YAGSALMRDE RLATKIFEAT VKAVKIPVTV KMRMGWDDNT 150
KNAPTLAVIA ASSGVQMVTV HGRTRCQFYS GNANWDFIRV VKEAVKIPVI 200
ANGDITNFAK AKEALQKSGA DGIMVGRGVY GKPWLISQIA YYLKTGKEKP 250
APSIAEQLDI IIKHYDAIID YYGKSVGVPI ARKHIIWYSS GLPSSAEFRC 300
AVNLMNDPIA VKEKIAEFYM SVMDANK 327
Length:327
Mass (Da):35,691
Last modified:October 11, 2004 - v1
Checksum:iAB4DD899752814E5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017197 Genomic DNA. Translation: AAU03499.1.
RefSeqiYP_066981.1. NC_006142.1.

Genome annotation databases

EnsemblBacteriaiAAU03499; AAU03499; RT0010.
GeneIDi2958537.
KEGGirty:RT0010.
PATRICi17909170. VBIRicTyp34752_0009.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017197 Genomic DNA. Translation: AAU03499.1 .
RefSeqi YP_066981.1. NC_006142.1.

3D structure databases

ProteinModelPortali Q68XZ3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 257363.RT0010.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAU03499 ; AAU03499 ; RT0010 .
GeneIDi 2958537.
KEGGi rty:RT0010.
PATRICi 17909170. VBIRicTyp34752_0009.

Phylogenomic databases

eggNOGi COG0042.
HOGENOMi HOG000217855.
OMAi RYQKDKI.
OrthoDBi EOG6VHZFQ.

Enzyme and pathway databases

BioCyci RTYP257363:GJEQ-10-MONOMER.

Family and domain databases

Gene3Di 1.10.1200.80. 1 hit.
3.20.20.70. 1 hit.
InterProi IPR013785. Aldolase_TIM.
IPR024036. tRNA-dHydroUridine_Synthase_C.
IPR004652. tRNA_dU_NifR3.
IPR001269. tRNA_hU_synthase.
IPR018517. tRNA_hU_synthase_CS.
[Graphical view ]
PANTHERi PTHR11082. PTHR11082. 1 hit.
Pfami PF01207. Dus. 1 hit.
[Graphical view ]
PIRSFi PIRSF006621. Dus. 1 hit.
TIGRFAMsi TIGR00737. nifR3_yhdG. 1 hit.
PROSITEi PS01136. UPF0034. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-144 / Wilmington.

Entry informationi

Entry nameiDUS_RICTY
AccessioniPrimary (citable) accession number: Q68XZ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: October 11, 2004
Last modified: May 14, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia typhi
    Rickettsia typhi (strain Wilmington): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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