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Q68XZ3 (DUS_RICTY) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable tRNA-dihydrouridine synthase
EC=1.-.-.-
Gene names
Name:dus
Ordered Locus Names:RT0010
OrganismRickettsia typhi (strain ATCC VR-144 / Wilmington) [Complete proteome] [HAMAP]
Taxonomic identifier257363 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group ›

Protein attributes

Sequence length327 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs By similarity.

Cofactor

FAD By similarity.

Sequence similarities

Belongs to the dus family.

Ontologies

Keywords
   Biological processtRNA processing
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtRNA dihydrouridine synthesis

Inferred from electronic annotation. Source: GOC

   Molecular_functionflavin adenine dinucleotide binding

Inferred from electronic annotation. Source: InterPro

tRNA dihydrouridine synthase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 327327Probable tRNA-dihydrouridine synthase
PRO_0000280961

Sequences

Sequence LengthMass (Da)Tools
Q68XZ3 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: AB4DD899752814E5

FASTA32735,691
        10         20         30         40         50         60 
MIKIGNIELS SNVILAPMSN ITDLEFRKLV KRFGAGLVVS EMIASRAMIM KSRQSMQKCA 

        70         80         90        100        110        120 
IMHDDPTSAC VQLAGCEPDV IADAAKMNED MGAKIIDLNF GCPAKKVVGG YAGSALMRDE 

       130        140        150        160        170        180 
RLATKIFEAT VKAVKIPVTV KMRMGWDDNT KNAPTLAVIA ASSGVQMVTV HGRTRCQFYS 

       190        200        210        220        230        240 
GNANWDFIRV VKEAVKIPVI ANGDITNFAK AKEALQKSGA DGIMVGRGVY GKPWLISQIA 

       250        260        270        280        290        300 
YYLKTGKEKP APSIAEQLDI IIKHYDAIID YYGKSVGVPI ARKHIIWYSS GLPSSAEFRC 

       310        320 
AVNLMNDPIA VKEKIAEFYM SVMDANK

« Hide

References

[1]"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae."
McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. expand/collapse author list , Hong C., Yu X.-J., Walker D.H., Weinstock G.M.
J. Bacteriol. 186:5842-5855(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017197 Genomic DNA. Translation: AAU03499.1.
RefSeqYP_066981.1. NC_006142.1.

3D structure databases

ProteinModelPortalQ68XZ3.
ModBaseSearch...

Protein-protein interaction databases

STRING257363.RT0010.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAU03499; AAU03499; RT0010.
GeneID2958537.
KEGGrty:RT0010.
PATRIC17909170. VBIRicTyp34752_0009.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0042.
HOGENOMHOG000217855.
OMAPIARKHI.
ProtClustDBCLSK870702.

Enzyme and pathway databases

BioCycRTYP257363:GJEQ-10-MONOMER.

Family and domain databases

Gene3D1.10.1200.80. 1 hit.
3.20.20.70. 1 hit.
InterProIPR013785. Aldolase_TIM.
IPR024036. tRNA-dHydroUridine_Synthase_C.
IPR004652. tRNA_dU_NifR3.
IPR001269. tRNA_hU_synthase.
IPR018517. tRNA_hU_synthase_CS.
[Graphical view]
PANTHERPTHR11082. PTHR11082. 1 hit.
PfamPF01207. Dus. 1 hit.
[Graphical view]
PIRSFPIRSF006621. Dus. 1 hit.
TIGRFAMsTIGR00737. nifR3_yhdG. 1 hit.
PROSITEPS01136. UPF0034. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDUS_RICTY
AccessionPrimary (citable) accession number: Q68XZ3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: October 11, 2004
Last modified: May 1, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Rickettsia typhi

Rickettsia typhi (strain Wilmington): entries and gene names

SIMILARITY comments

Index of protein domains and families

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