Reviewed, UniProtKB/Swiss-Prot Q68XY2 (SECF_RICTY)

Names and origin

Protein names

Recommended name:
    Protein-export membrane protein secF

Gene names

Name:	secF
Ordered Locus Names:	RT0022

Organism

Rickettsia typhi [Complete proteome] [HAMAP]

Taxonomic identifier

785 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length	308 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Involved in protein export By similarity.
Subunit structure	Part of the prokaryotic protein translocation apparatus which comprise secA, secB, secD, secE, secF, secG and secY By similarity.
Subcellular location	Cell membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the secD/secF family. SecF subfamily.

Ontologies

Keywords
Biological process	Protein transport Translocation Transport
Cellular component	Cell membrane Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	intracellular protein transport Inferred from electronic annotation. Source: InterPro protein secretion by the type II secretion system Inferred from electronic annotation. Source: InterPro transmembrane transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW type II protein secretion system complex Inferred from electronic annotation. Source: InterPro
Molecular function	P-P-bond-hydrolysis-driven protein transmembrane transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 308	308	Protein-export membrane protein secF		PRO_0000272640
Regions
	Transmembrane	36 – 56	21	Potential
	Transmembrane	140 – 160	21	Potential
	Transmembrane	164 – 184	21	Potential
	Transmembrane	194 – 214	21	Potential
	Transmembrane	246 – 266	21	Potential
	Transmembrane	272 – 292	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q68XY2-1 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: 7E1FB0CC35708C73	FASTA	308	34,940
	10 20 30 40 50 60 MQIYPLRFVP NKINFDFMNF KKVSYSFSII LSLISLIWIG IYKFNFGIDF VGGIVIEVRL 70 80 90 100 110 120 DRAPDLPKMR AVLSALGIGE VVLQNFESEH DLSIRFGSSS EENLMKNIDI IKTSLRNNFP 130 140 150 160 170 180 YNFEYRKVDF VGPQVGRHLI EAGAMAMLFS FLAIMVYIGV RFEWYFGFGI LIALVHDVIL 190 200 210 220 230 240 ALGFMSITKL DFNLSTIAAV LTIIGYSVND SVVIYDRIRE NLRKYHKKNI TEIINLSINE 250 260 270 280 290 300 TLSRTILTVI TTLLANLALI LFGGKAIHSF SVLVFFGIIA GTYSSIFISA PILTIFANRK FNKKVIER

References

[1]

"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae." McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. , Hong C., Yu X.-J., Walker D.H., Weinstock G.M. J. Bacteriol. 186:5842-5855(2004) [PubMed: 15317790] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017197 Genomic DNA. Translation: AAU03510.1.
RefSeq	YP_066992.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2958489.
GenomeReviews	Gene locus RT0022 in contig AE017197_GR.
KEGG	rty:RT0022.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG465293.
OMA	ANLHDVI.
Enzyme and pathway databases
BioCyc	RTYP257363:RT0022-MON.
Family and domain databases
InterPro	IPR003335. SecD_SecF. IPR005665. SecF. [Graphical view]
Pfam	PF07549. Sec_GG. 1 hit. PF02355. SecD_SecF. 1 hit. [Graphical view]
PRINTS	PR01755. SECFTRNLCASE.
ProtoNet	Search...

Entry information

Entry name

SECF_RICTY

Accession

Primary (citable) accession number: Q68XY2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2007
Last sequence update:	October 11, 2004
Last modified:	December 15, 2009
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)