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Q68XY2 (SECF_RICTY) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein translocase subunit SecF
Gene names
Name:secF
Ordered Locus Names:RT0022
OrganismRickettsia typhi (strain ATCC VR-144 / Wilmington) [Complete proteome] [HAMAP]
Taxonomic identifier257363 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group

Protein attributes

Sequence length308 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA By similarity. HAMAP-Rule MF_01464

Subunit structure

Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC By similarity.

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01464.

Sequence similarities

Belongs to the SecD/SecF family. SecF subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 308308Protein translocase subunit SecF HAMAP-Rule MF_01464
PRO_0000272640

Regions

Transmembrane23 – 4220Helical; Potential
Transmembrane140 – 16021Helical; Potential
Transmembrane164 – 18421Helical; Potential
Transmembrane194 – 21421Helical; Potential
Transmembrane246 – 26621Helical; Potential
Transmembrane272 – 29221Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q68XY2 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 7E1FB0CC35708C73

FASTA30834,940
        10         20         30         40         50         60 
MQIYPLRFVP NKINFDFMNF KKVSYSFSII LSLISLIWIG IYKFNFGIDF VGGIVIEVRL 

        70         80         90        100        110        120 
DRAPDLPKMR AVLSALGIGE VVLQNFESEH DLSIRFGSSS EENLMKNIDI IKTSLRNNFP 

       130        140        150        160        170        180 
YNFEYRKVDF VGPQVGRHLI EAGAMAMLFS FLAIMVYIGV RFEWYFGFGI LIALVHDVIL 

       190        200        210        220        230        240 
ALGFMSITKL DFNLSTIAAV LTIIGYSVND SVVIYDRIRE NLRKYHKKNI TEIINLSINE 

       250        260        270        280        290        300 
TLSRTILTVI TTLLANLALI LFGGKAIHSF SVLVFFGIIA GTYSSIFISA PILTIFANRK 


FNKKVIER 

« Hide

References

[1]"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae."
McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. expand/collapse author list , Hong C., Yu X.-J., Walker D.H., Weinstock G.M.
J. Bacteriol. 186:5842-5855(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017197 Genomic DNA. Translation: AAU03510.1.
RefSeqYP_066992.1. NC_006142.1.

3D structure databases

ProteinModelPortalQ68XY2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING257363.RT0022.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAU03510; AAU03510; RT0022.
GeneID2958489.
KEGGrty:RT0022.
PATRIC17909194. VBIRicTyp34752_0020.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0341.
HOGENOMHOG000245916.
KOK03074.
OMAEEMLIKF.
OrthoDBEOG676Z5R.

Enzyme and pathway databases

BioCycRTYP257363:GJEQ-23-MONOMER.

Family and domain databases

HAMAPMF_01464_B. SecF_B.
InterProIPR022813. SecD/SecF_arch_bac.
IPR022645. SecD/SecF_bac.
IPR022646. SecD/SecF_CS.
IPR005665. SecF_bac.
[Graphical view]
PfamPF07549. Sec_GG. 1 hit.
PF02355. SecD_SecF. 1 hit.
[Graphical view]
PRINTSPR01755. SECFTRNLCASE.
TIGRFAMsTIGR00916. 2A0604s01. 1 hit.
TIGR00966. 3a0501s07. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSECF_RICTY
AccessionPrimary (citable) accession number: Q68XY2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: October 11, 2004
Last modified: May 14, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia typhi

Rickettsia typhi (strain Wilmington): entries and gene names