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Q68XX8 (ACKA_RICTY) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:RT0026
OrganismRickettsia typhi (strain ATCC VR-144 / Wilmington) [Complete proteome] [HAMAP]
Taxonomic identifier257363 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length385 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 385385Acetate kinase HAMAP MF_00020
PRO_0000107606

Sequences

Sequence LengthMass (Da)Tools
Q68XX8 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 6226C8A5676DA515

FASTA38543,381
        10         20         30         40         50         60 
MKDVILIANA GSSSLKISIF GIQNKKVKDK IYNIFLEKNN NKILFYINQK QESAISIKDN 

        70         80         90        100        110        120 
AIEMMINLFE EWWTKQSALN LIATGHRIVH GGKNFNKPVI VNEKIIKELR VLIPLSPLHQ 

       130        140        150        160        170        180 
PYNLQVLDLF FQKYKDISHI ICFDTSFHYT NPPITKAFGL PKQYYDKGIM RYGFHGLSYQ 

       190        200        210        220        230        240 
YVSSHFKEIT MEDLPTKTII AHLGSGSSLC AIKNGLSLTS SMGFSVLDGV MMATRTGNLD 

       250        260        270        280        290        300 
PGVVLYLINH EKMTMKEITE LLYKKSGLLG ISGESSDMRT LITNNSHDSK FAVELFVYRI 

       310        320        330        340        350        360 
VLEIGKLIAA LEGIDCIIFT AGIGQNSAVI REMISGKLSW LGIKIDYGKN QKNEHRISTK 

       370        380 
GSKVKVFVVP TNEELIIAEE VMKFL

« Hide

References

[1]"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae."
McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. expand/collapse author list , Hong C., Yu X.-J., Walker D.H., Weinstock G.M.
J. Bacteriol. 186:5842-5855(2004) [PubMed: 15317790] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017197 Genomic DNA. Translation: AAU03514.1.
RefSeqYP_066996.1. NC_006142.1.

3D structure databases

ProteinModelPortalQ68XX8.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2958568.
GenomeReviewsGene locus RT0026 in contig AE017197_GR.
KEGGrty:RT0026.
PATRIC17909202. VBIRicTyp34752_0024.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG285863.
OMASAVIREM.
ProtClustDBCLSK870749.

Enzyme and pathway databases

BioCycRTYP257363:RT0026-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_RICTY
AccessionPrimary (citable) accession number: Q68XX8
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: October 11, 2004
Last modified: January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Rickettsia typhi

Rickettsia typhi (strain Wilmington): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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