Q68XX6 (Y028_RICTY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized lipoprotein RT0028

Gene names

Ordered Locus Names:

RT0028

Organism

Rickettsia typhi (strain ATCC VR-144 / Wilmington) [Complete proteome] [HAMAP]

Taxonomic identifier

257363 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length	1154 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Cell membrane; Multi-pass membrane protein Potential. Cell membrane; Lipid-anchor Potential.
Sequence similarities	Belongs to the trbL/virB6 family.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Signal Transmembrane Transmembrane helix
PTM	Lipoprotein Palmitate
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein secretion by the type IV secretion system Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 18	18	Potential
	Chain	19 – 1154	1136	Uncharacterized lipoprotein RT0028		PRO_0000269913
Regions
	Transmembrane	288 – 308	21	Helical; Potential
	Transmembrane	394 – 414	21	Helical; Potential
	Transmembrane	423 – 443	21	Helical; Potential
	Transmembrane	458 – 478	21	Helical; Potential
	Compositional bias	397 – 482	86	Ile-rich
Amino acid modifications
	Lipidation	19	1	N-palmitoyl cysteine Potential
	Lipidation	19	1	S-diacylglycerol cysteine Potential

Sequences

	Sequence		Length	Mass (Da)
	Q68XX6 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: 376EFF64D521D4A4	FASTA	1,154	132,601
	10 20 30 40 50 60 MKRNIFIKLL ISLLLLSSCT GDTCIDPDDF GFIKFNVSSR YNPEEITSRH EGDQVAPWRD 70 80 90 100 110 120 SAYKVNGYPL TIMVRPWNYI LGDKNTSGQL SAWCPWYGQK NNTTTLAPFC IKLQPCTFWD 130 140 150 160 170 180 NTRLDMCTPN PENRNDAMIS NPPCIMTDGV GLYFLIAAKN TDPNISPDSQ RKPQGITRHL 190 200 210 220 230 240 GELTSSVGYE FYSISSTGQL LKAGGINYQY NGEDKSKYAQ SPLYFKIIDK FYDDNSGQYR 250 260 270 280 290 300 LVIKSGVSDT RPDPLQFLTD LIKDVLFGKN GIIKKTYQQI VDTPGYRISV SAILTLYIMF 310 320 330 340 350 360 TGLSFLIGNI NLTHVELIIR IFKISIISIL LSSDKAWTFF HDYLFVFFID GVQQILQIIN 370 380 390 400 410 420 EAAATGPGSQ SLLGLLISTQ TLSKLFSLLF VDWLGFIYII LYLIALYFIF FLIFKATIIY 430 440 450 460 470 480 LTALITIGMM IIMGPIFICF MLFNITRSLF ENWLRQLISY ALQPIILFAG IAFISMIIRT 490 500 510 520 530 540 EIYSTLGFGV CKHDFPNLGP INEIFGSFLE DIDPSLSNSI FYWWFPVPMK GGINNFHKAK 550 560 570 580 590 600 ILVPNDHIVV DDSCKNNHDK CKHCAAYECI DERYIELPFL DLVKDSTRIN NFINGKFVQL 610 620 630 640 650 660 DGILLIFVSI YLLSKFNDTA ISTAQFIAGT SGNLTDIQKV NQQSYESVSQ QINRPLNYVA 670 680 690 700 710 720 KTISTPVTSR ISAGTAQANM FFAEKFENMM MRRLEKQALS SSANKVVQNE VKRKYGIDSK 730 740 750 760 770 780 DVNMNAIKDY EDGISRLLNN LPKGNELKVK ELSQMKFTQL RDKISANKYD VQDYTTLSTE 790 800 810 820 830 840 QKTELDKLLK DANLRVLASD ANFTKDYQEA YKHAHQEMSG RGIGLFGKNI GVLRSWQEME 850 860 870 880 890 900 HSINVKRKLK EEKRIGIGEK IYAGYTGIKR AALTTIVGKD LRDAYEGNLT SAEWHDFEYN 910 920 930 940 950 960 DPRLRTYSEK LKDDEKARER EKLRMHINKE TLAVQADILS PEYLVKLEKA GRKSDVEYYQ 970 980 990 1000 1010 1020 ELAQRQLIYD VHSKLFEEGE PVMMGDRFMR EKATDSQMRD MIDNAHKKYV ELIDVDRYTR 1030 1040 1050 1060 1070 1080 RQEYYDIIYE KAKENLEQTY KEVQDHFKRD NISIEEMPAL IAQKVKDTNA GSEIDKKITE 1090 1100 1110 1120 1130 1140 ELNNFNADVK NYEYSTAVLN KIEDRKQTIT DVVNVQIDKI NKYRENAKME QYVKPILNEG 1150 RKLRTLEDHF KNMK

References

[1]

"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae." McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. , Hong C., Yu X.-J., Walker D.H., Weinstock G.M. J. Bacteriol. 186:5842-5855(2004) [PubMed: 15317790] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017197 Genomic DNA. Translation: AAU03516.1.
RefSeq	YP_066998.1. NC_006142.1.
3D structure databases
ProteinModelPortal	Q68XX6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2958491.
GenomeReviews	Gene locus RT0028 in contig AE017197_GR.
KEGG	rty:RT0028.
PATRIC	17909206. VBIRicTyp34752_0026.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG664068.
OMA	ECIDERY.
ProtClustDB	CLSK870748.
Enzyme and pathway databases
BioCyc	RTYP257363:RT0028-MONOMER.
Family and domain databases
InterPro	IPR007688. Conjugal_tfr_TrbL/VirB6. [Graphical view]
KO	K03201.
Pfam	PF04610. TrbL. 1 hit. [Graphical view]
PROSITE	PS51257. PROKAR_LIPOPROTEIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y028_RICTY

Accession

Primary (citable) accession number: Q68XX6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 9, 2007
Last sequence update:	October 11, 2004
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program