Reviewed,
UniProtKB/Swiss-Prot Q68XV7 (KDTA_RICTY)
Last modified
December 15, 2009.
Version 35.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: 3-deoxy-D-manno-octulosonic-acid transferase EC=2.4.-.- Alternative name(s): KDO transferase | ||||||
| Gene names |
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| Organism | Rickettsia typhi [Complete proteome] [HAMAP] | ||||||
| Taxonomic identifier | 785 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group |
Protein attributes
| Sequence length | 462 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA) By similarity. |
| Pathway | Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. |
| Subcellular location | Cell inner membrane; Single-pass membrane protein Potential. |
| Sequence similarities | Belongs to the glycosyltransferase 1 family. Contains 1 RPE1 insert domain. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Lipopolysaccharide biosynthesis |
| Cellular component | Cell inner membrane Cell membrane Membrane |
| Domain | Signal-anchor Transmembrane |
| Molecular function | Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | lipopolysaccharide biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membraneInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | sugar binding Inferred from electronic annotation. Source: InterPro transferase activityInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae." McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. Weinstock G.M.J. Bacteriol. 186:5842-5855(2004) [PubMed: 15317790] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-144 / Wilmington. |
Cross-references
Sequence databases | |
|---|---|
| AE017197 Genomic DNA. Translation: AAU03535.1. | |
| RefSeq | YP_067017.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 2958750. |
| GenomeReviews | Gene locus RT0048 in contig AE017197_GR. |
| KEGG | rty:RT0048. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | HBG664037. |
| OMA | VQHCYLP. |
Enzyme and pathway databases | |
| BioCyc | RTYP257363:RT0048-MON. |
Family and domain databases | |
| InterPro | IPR007507. Glycos_transf_N. [Graphical view] |
| Pfam | PF04413. Glycos_transf_N. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | KDTA_RICTY | ||||||||
| Accession | Primary (citable) accession number: Q68XV7 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| Rickettsia typhi Rickettsia typhi (strain Wilmington): entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with


