Reviewed, UniProtKB/Swiss-Prot Q68XV6 (EFTS_RICTY)

Names and origin

Protein names

Recommended name:
    Elongation factor Ts
      Short name=EF-Ts

Gene names

Name:	tsf
Ordered Locus Names:	RT0049

Organism

Rickettsia typhi [Complete proteome] [HAMAP]

Taxonomic identifier

785 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length	309 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. HAMAP MF_00050
Subcellular location	Cytoplasm.
Sequence similarities	Belongs to the EF-Ts family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Elongation factor
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translational elongation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	translation elongation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 309	309	Elongation factor Ts HAMAP MF_00050		PRO_0000161187
Regions
	Region	82 – 85	4	Involved in Mg(2+) ion dislocation from EF-Tu By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q68XV6-1 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: A27EA2017E9FD4B9	FASTA	309	34,047
	10 20 30 40 50 60 MSEINISAAA VKELREKTGA GMMDCKKALI ETSGNFEEAI DFLRKKGLAA AVKKFGRIAS 70 80 90 100 110 120 EGLTAIKING LTSVVIEVNS ETDFVARNEQ FQNLVKDIVN LAIIAQNIDA LKISKMQSGK 130 140 150 160 170 180 SVEEEIIENI ATIGENLTLR RMDILEISNG AIGSYVHNEV VPHLGKISVL VGLESNAKDK 190 200 210 220 230 240 AKLAALAKQI AVHVAGNNPQ SIDTLSLDQA LVERERKVFF EKSKEEGKPD HIIEKMVEGR 250 260 270 280 290 300 IRKFFSEVVL LQQNFLFEPK LTVAEVIKNA EQELGAEIKI TKFIRYALGE GIEHEEKNFA DEVASITKC

References

[1]

"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae." McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. , Hong C., Yu X.-J., Walker D.H., Weinstock G.M. J. Bacteriol. 186:5842-5855(2004) [PubMed: 15317790] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017197 Genomic DNA. Translation: AAU03536.1.
RefSeq	YP_067018.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2958791.
GenomeReviews	Gene locus RT0049 in contig AE017197_GR.
KEGG	rty:RT0049.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q68XV6.
OMA	YLHGTRI
Enzyme and pathway databases
BioCyc	RTYP257363:RT0049-MON.
Family and domain databases
HAMAP	MF_00050. [Tree]
InterPro	IPR001816. Transl_elong_EFTs/EF1B. IPR014039. Transl_elong_EFTs/EF1B_dimer. IPR018101. Transl_elong_Ts_CS. IPR009060. UBA-like. IPR000449. UBA/transl_elong_EF1B_N. [Graphical view]
Gene3D	G3DSA:3.30.479.20. Transl_elong_EFTs/EF1B_dimer. 2 hits.
PANTHER	PTHR11741. Transl_elong_EFTs/EF1B. 1 hit.
Pfam	PF00889. EF_TS. 1 hit. PF00627. UBA. 1 hit. [Graphical view]
TIGRFAMs	TIGR00116. tsf. 1 hit.
PROSITE	PS01126. EF_TS_1. 1 hit. PS01127. EF_TS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EFTS_RICTY

Accession

Primary (citable) accession number: Q68XV6

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 2005
Last sequence update:	October 11, 2004
Last modified:	November 24, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)