Reviewed, UniProtKB/Swiss-Prot Q68XU4 (SECB_RICTY)

Names and origin

Protein names

Recommended name:
    Protein-export protein secB

Gene names

Name:	secB
Ordered Locus Names:	RT0062

Organism

Rickettsia typhi [Complete proteome] [HAMAP]

Taxonomic identifier

785 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length	152 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor secA By similarity.
Subunit structure	Homotetramer, a dimer of dimers. One homotetramer interacts with 1 secA dimer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the secB family.

Ontologies

Keywords
Biological process	Protein transport Translocation Transport
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein folding Inferred from electronic annotation. Source: HAMAP protein tetramerization Inferred from electronic annotation. Source: InterPro protein transport Inferred from electronic annotation. Source: HAMAP transmembrane transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	unfolded protein binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 152	152	Protein-export protein secB HAMAP MF_00821		PRO_0000055411
Experimental info
	Sequence conflict	6	1	S → T in AAL82789. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q68XU4-1 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: CF6E45E2B145C5C3	FASTA	152	17,110
	10 20 30 40 50 60 MSTINSDTSE AMPHISVNAQ YIKDLSLENP SAPSSLAALD QRPQIDLSLD INITNLSDEN 70 80 90 100 110 120 FYEVELNIEA IARNEKYKLF QIELKYAGVF NLINIDSEQH PILLSVHCPA MIFPFARKII 130 140 150 ASCTQDAGFQ PLMIDPIDFG ALYHKKMSEH QN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Characterization of the Sec operon of the typhus group Rickettsia." On'gele E.A., Radulovic S., Azad A.F. Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae." McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. , Hong C., Yu X.-J., Walker D.H., Weinstock G.M. J. Bacteriol. 186:5842-5855(2004) [PubMed: 15317790] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AY078351 Genomic DNA. Translation: AAL82789.1. AE017197 Genomic DNA. Translation: AAU03548.1.
RefSeq	YP_067030.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2958688.
GenomeReviews	Gene locus RT0062 in contig AE017197_GR.
KEGG	rty:RT0062.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q68XU4.
OMA	GFPPLMI
Enzyme and pathway databases
BioCyc	RTYP257363:RT0062-MON.
Family and domain databases
HAMAP	MF_00821. [Tree]
InterPro	IPR003708. SecB. [Graphical view]
Gene3D	G3DSA:3.10.420.10. SecB. 1 hit.
Pfam	PF02556. SecB. 1 hit. [Graphical view]
PRINTS	PR01594. SECBCHAPRONE.
TIGRFAMs	TIGR00809. secB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SECB_RICTY

Accession

Primary (citable) accession number: Q68XU4
Secondary accession number(s): Q8RLP6

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	October 11, 2004
Last modified:	November 24, 2009
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)