Reviewed, UniProtKB/Swiss-Prot Q68XU3 (DCD_RICTY)

Names and origin

Protein names

Recommended name:
    Deoxycytidine triphosphate deaminase
      Short name=dCTP deaminase
    EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	RT0063

Organism

Rickettsia typhi [Complete proteome] [HAMAP]

Taxonomic identifier

785 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length	188 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP protein binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 188	188	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_0000274886

Sequences

	Sequence		Length	Mass (Da)
	Q68XU3-1 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: 034B81A961394DD2	FASTA	188	21,345
	10 20 30 40 50 60 MTIMSDKWIK DAVIKQSMIR PFAEKQVRVH NKEKIISYGL SSYGYDARVS NEFKIFTNIN 70 80 90 100 110 120 STTVDPKNFS EDNLVDREVD ECIIPPNSFA LGRTIEYFKI PRDVLVICVG KSTYARCGII 130 140 150 160 170 180 VNVTPLEPEW EGHVTLEFSN TTPLPAKIYA NEGACQFLFL KSDQICDTSY AERQGKYMKQ VGVTLPLT

References

[1]

"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae." McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. , Hong C., Yu X.-J., Walker D.H., Weinstock G.M. J. Bacteriol. 186:5842-5855(2004) [PubMed: 15317790] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017197 Genomic DNA. Translation: AAU03549.1.
RefSeq	YP_067031.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2959178.
GenomeReviews	Gene locus RT0063 in contig AE017197_GR.
KEGG	rty:RT0063.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q68XU3.
OMA	MEYFRIP
Enzyme and pathway databases
BioCyc	RTYP257363:RT0063-MON.
BRENDA	3.5.4.13. 281221.
Family and domain databases
HAMAP	MF_00146. [Tree]
InterPro	IPR011962. dCTP_deam. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_RICTY

Accession

Primary (citable) accession number: Q68XU3

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 6, 2007
Last sequence update:	October 11, 2004
Last modified:	November 24, 2009
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)