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Protein

Deoxyguanosinetriphosphate triphosphohydrolase-like protein

Gene

RT0068

Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. dGTPase activity Source: InterPro
  2. magnesium ion binding Source: InterPro

GO - Biological processi

  1. GTP metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciRTYP257363:GJEQ-71-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Deoxyguanosinetriphosphate triphosphohydrolase-like proteinUniRule annotation
Gene namesi
Ordered Locus Names:RT0068
OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
Taxonomic identifieri257363 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000000604: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 384384Deoxyguanosinetriphosphate triphosphohydrolase-like proteinPRO_0000272409Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi257363.RT0068.

Structurei

3D structure databases

ProteinModelPortaliQ68XT8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dGTPase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0232.
HOGENOMiHOG000082148.
KOiK01129.
OMAiQDALNEC.
OrthoDBiEOG64XXMV.

Family and domain databases

Gene3Di1.10.3210.10. 2 hits.
HAMAPiMF_01212. dGTPase_type2.
InterProiIPR006261. dGTP_triP_hydro.
IPR023023. dGTP_triP_hydro_type2.
IPR003607. HD/PDEase_dom.
IPR006674. HD_domain.
IPR026875. PHydrolase_assoc_dom.
[Graphical view]
PfamiPF01966. HD. 1 hit.
PF13286. HD_assoc. 1 hit.
[Graphical view]
SMARTiSM00471. HDc. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01353. dGTP_triPase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q68XT8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLASYASDPL KSRGRLYKEI PTYYRNEFER DRDRIIHTNA FRRLQYKTQV
60 70 80 90 100
FINHEEGDHY RNRLTHSLEV ATVARSVANT LNLSSDLAET IALAHDLGHT
110 120 130 140 150
PFGHVGEKAL NECMKEYNGF SHNSQSLKIL TLLEKRYAAY NGVNLTWEVL
160 170 180 190 200
EGIVKHNGPI LGAINEYVAE YNKQNDLELN TYASAEAQIA SLADDISYIS
210 220 230 240 250
HDLEDSIIAK IIDFNNLAEL QYIDNYVFKL KSKFKDISPS CLIYEIVRKL
260 270 280 290 300
IHELITDLLL QTKENLKKEK ITNINEIRNL HYQIVDFTEK TNERINETKK
310 320 330 340 350
FLHKRVYESN KMIAISIKCT KIVQGLFKIY MDDINLLPTN WKILIDSNET
360 370 380
YSKARVIADY IAGMTDRFAI QEYNQLCAPK FNKI
Length:384
Mass (Da):44,516
Last modified:October 11, 2004 - v1
Checksum:iA6F239F9E5A58146
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017197 Genomic DNA. Translation: AAU03554.1.
RefSeqiYP_067036.1. NC_006142.1.

Genome annotation databases

EnsemblBacteriaiAAU03554; AAU03554; RT0068.
GeneIDi2958699.
KEGGirty:RT0068.
PATRICi17909294. VBIRicTyp34752_0068.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017197 Genomic DNA. Translation: AAU03554.1.
RefSeqiYP_067036.1. NC_006142.1.

3D structure databases

ProteinModelPortaliQ68XT8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi257363.RT0068.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAU03554; AAU03554; RT0068.
GeneIDi2958699.
KEGGirty:RT0068.
PATRICi17909294. VBIRicTyp34752_0068.

Phylogenomic databases

eggNOGiCOG0232.
HOGENOMiHOG000082148.
KOiK01129.
OMAiQDALNEC.
OrthoDBiEOG64XXMV.

Enzyme and pathway databases

BioCyciRTYP257363:GJEQ-71-MONOMER.

Family and domain databases

Gene3Di1.10.3210.10. 2 hits.
HAMAPiMF_01212. dGTPase_type2.
InterProiIPR006261. dGTP_triP_hydro.
IPR023023. dGTP_triP_hydro_type2.
IPR003607. HD/PDEase_dom.
IPR006674. HD_domain.
IPR026875. PHydrolase_assoc_dom.
[Graphical view]
PfamiPF01966. HD. 1 hit.
PF13286. HD_assoc. 1 hit.
[Graphical view]
SMARTiSM00471. HDc. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01353. dGTP_triPase. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-144 / Wilmington.

Entry informationi

Entry nameiDGTL1_RICTY
AccessioniPrimary (citable) accession number: Q68XT8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: October 11, 2004
Last modified: January 7, 2015
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia typhi
    Rickettsia typhi (strain Wilmington): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.