Reviewed, UniProtKB/Swiss-Prot Q68XS2 (LGT_RICTY)

Names and origin

Protein names

Recommended name:
    Prolipoprotein diacylglyceryl transferase
    EC=2.4.99.-

Gene names

Name:	lgt
Ordered Locus Names:	RT0084

Organism

Rickettsia typhi [Complete proteome] [HAMAP]

Taxonomic identifier

785 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length	259 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins By similarity.
Pathway	Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer). HAMAP MF_01147
Subcellular location	Cell inner membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the lgt family.

Ontologies

Keywords
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipoprotein biosynthetic process Inferred from electronic annotation. Source: HAMAP protein lipoylation Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: HAMAP
Molecular function	phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 259	259	Prolipoprotein diacylglyceryl transferase HAMAP MF_01147		PRO_0000172665
Regions
	Transmembrane	9 – 29	21	Potential
	Transmembrane	55 – 75	21	Potential
	Transmembrane	92 – 112	21	Potential
	Transmembrane	117 – 137	21	Potential
	Transmembrane	172 – 192	21	Potential
	Transmembrane	201 – 221	21	Potential
	Transmembrane	228 – 248	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q68XS2-1 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: F73D6401EFD8EE31	FASTA	259	29,438
	10 20 30 40 50 60 MILPNINPII FSIGPFSISW YSLSYVVGIL LGWFYATKII EKFKPEITKK HIEDFITYAI 70 80 90 100 110 120 IGIIVGGRLG YVLLYNPLKY FANPIEILKT YEGGMSFHGA TIGIIISAYL FCQKYKINFL 130 140 150 160 170 180 SLTDIITTVV PIGLFLGRIA NFINCELYGR ITNSSFGIIF PNSDLEPRHP SQLYEAFFEG 190 200 210 220 230 240 LILFCILAYA VFRHDTLKKQ GLNSGIYLIF YSLFRIIIEM FREPDIQIGF ILDSLTMGQI 250 LSAPMLLLGS YLICRLNSK

References

[1]

"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae." McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. , Hong C., Yu X.-J., Walker D.H., Weinstock G.M. J. Bacteriol. 186:5842-5855(2004) [PubMed: 15317790] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017197 Genomic DNA. Translation: AAU03570.1.
RefSeq	YP_067052.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2959240.
GenomeReviews	Gene locus RT0084 in contig AE017197_GR.
KEGG	rty:RT0084.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q68XS2.
OMA	NGELYGK
Enzyme and pathway databases
BioCyc	RTYP257363:RT0084-MON.
Family and domain databases
HAMAP	MF_01147. [Tree]
InterPro	IPR001640. Prolipoprot_diAcglycer_Trfase. [Graphical view]
Pfam	PF01790. LGT. 1 hit. [Graphical view]
TIGRFAMs	TIGR00544. lgt. 1 hit.
PROSITE	PS01311. LGT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

LGT_RICTY

Accession

Primary (citable) accession number: Q68XS2

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 26, 2005
Last sequence update:	October 11, 2004
Last modified:	November 3, 2009
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)