Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q68XS0

- SDHB_RICTY

UniProt

Q68XS0 - SDHB_RICTY

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Succinate dehydrogenase iron-sulfur subunit

Gene

sdhB

Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Succinate + a quinone = fumarate + a quinol.

Cofactori

Protein has several cofactor binding sites:

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi80 – 801Iron-sulfur 1 (2Fe-2S)By similarity
Metal bindingi85 – 851Iron-sulfur 1 (2Fe-2S)By similarity
Metal bindingi100 – 1001Iron-sulfur 1 (2Fe-2S)By similarity
Metal bindingi171 – 1711Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi174 – 1741Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi177 – 1771Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi181 – 1811Iron-sulfur 3 (3Fe-4S)By similarity
Binding sitei186 – 1861Ubiquinone; shared with SdhD subunitBy similarity
Metal bindingi228 – 2281Iron-sulfur 3 (3Fe-4S)By similarity
Metal bindingi234 – 2341Iron-sulfur 3 (3Fe-4S)By similarity
Metal bindingi238 – 2381Iron-sulfur 2 (4Fe-4S)By similarity

GO - Molecular functioni

  1. 2 iron, 2 sulfur cluster binding Source: UniProtKB-KW
  2. 3 iron, 4 sulfur cluster binding Source: UniProtKB-KW
  3. 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
  4. electron carrier activity Source: InterPro
  5. metal ion binding Source: UniProtKB-KW
  6. succinate dehydrogenase (ubiquinone) activity Source: UniProtKB-EC

GO - Biological processi

  1. tricarboxylic acid cycle Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Transport, Tricarboxylic acid cycle

Keywords - Ligandi

2Fe-2S, 3Fe-4S, 4Fe-4S, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyciRTYP257363:GJEQ-91-MONOMER.
UniPathwayiUPA00223; UER01005.

Names & Taxonomyi

Protein namesi
Recommended name:
Succinate dehydrogenase iron-sulfur subunit (EC:1.3.5.1)
Gene namesi
Name:sdhB
Ordered Locus Names:RT0086
OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
Taxonomic identifieri257363 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000000604: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 261261Succinate dehydrogenase iron-sulfur subunitPRO_0000280984Add
BLAST

Interactioni

Subunit structurei

Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

Protein-protein interaction databases

STRINGi257363.RT0086.

Structurei

3D structure databases

ProteinModelPortaliQ68XS0.
SMRiQ68XS0. Positions 28-256.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini28 – 119922Fe-2S ferredoxin-typePROSITE-ProRule annotationAdd
BLAST
Domaini161 – 191314Fe-4S ferredoxin-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 2Fe-2S ferredoxin-type domain.PROSITE-ProRule annotation
Contains 1 4Fe-4S ferredoxin-type domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0479.
HOGENOMiHOG000160590.
KOiK00240.
OMAiSEPHWES.
OrthoDBiEOG6CK7MG.

Family and domain databases

Gene3Di3.10.20.30. 1 hit.
InterProiIPR001041. 2Fe-2S_ferredoxin-type.
IPR006058. 2Fe2S_fd_BS.
IPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR012675. Beta-grasp_dom.
IPR009051. Helical_ferredxn.
IPR004489. Succ_DH/fum_Rdtase_Fe-S.
IPR025192. Succ_DH/fum_Rdtase_N.
[Graphical view]
PfamiPF13085. Fer2_3. 1 hit.
PF13183. Fer4_8. 1 hit.
[Graphical view]
SUPFAMiSSF46548. SSF46548. 1 hit.
SSF54292. SSF54292. 1 hit.
TIGRFAMsiTIGR00384. dhsB. 1 hit.
PROSITEiPS00197. 2FE2S_FER_1. 1 hit.
PS51085. 2FE2S_FER_2. 1 hit.
PS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q68XS0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVELRLPSNS VVKKGRVHKA QQEMLKPRKV QVYRYDPDLN KNPTIDSFEI
60 70 80 90 100
DLSKTGPMVL DALIKIKNEI DSTLTFRRSC REGICGSCAM NIDGTNTLAC
110 120 130 140 150
IKPIEDISGD IKIYPLPHMK VVKDLVPDMS HFYTQYESIE PWLKNDNPAP
160 170 180 190 200
SNSERLQSIQ DREKLDGLYE CILCACCSTS CPSYWWNSDK YLGPAILLQA
210 220 230 240 250
YRWIADSRDD NTGARLEALE DPFKLYRCHT IMNCTKTCPK GLNPAKAIGR
260
VKSLIAERHG V
Length:261
Mass (Da):29,601
Last modified:October 11, 2004 - v1
Checksum:iF9CBCE4066008131
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017197 Genomic DNA. Translation: AAU03572.1.
RefSeqiYP_067054.1. NC_006142.1.

Genome annotation databases

EnsemblBacteriaiAAU03572; AAU03572; RT0086.
GeneIDi2959191.
KEGGirty:RT0086.
PATRICi17909340. VBIRicTyp34752_0091.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017197 Genomic DNA. Translation: AAU03572.1 .
RefSeqi YP_067054.1. NC_006142.1.

3D structure databases

ProteinModelPortali Q68XS0.
SMRi Q68XS0. Positions 28-256.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 257363.RT0086.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAU03572 ; AAU03572 ; RT0086 .
GeneIDi 2959191.
KEGGi rty:RT0086.
PATRICi 17909340. VBIRicTyp34752_0091.

Phylogenomic databases

eggNOGi COG0479.
HOGENOMi HOG000160590.
KOi K00240.
OMAi SEPHWES.
OrthoDBi EOG6CK7MG.

Enzyme and pathway databases

UniPathwayi UPA00223 ; UER01005 .
BioCyci RTYP257363:GJEQ-91-MONOMER.

Family and domain databases

Gene3Di 3.10.20.30. 1 hit.
InterProi IPR001041. 2Fe-2S_ferredoxin-type.
IPR006058. 2Fe2S_fd_BS.
IPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR012675. Beta-grasp_dom.
IPR009051. Helical_ferredxn.
IPR004489. Succ_DH/fum_Rdtase_Fe-S.
IPR025192. Succ_DH/fum_Rdtase_N.
[Graphical view ]
Pfami PF13085. Fer2_3. 1 hit.
PF13183. Fer4_8. 1 hit.
[Graphical view ]
SUPFAMi SSF46548. SSF46548. 1 hit.
SSF54292. SSF54292. 1 hit.
TIGRFAMsi TIGR00384. dhsB. 1 hit.
PROSITEi PS00197. 2FE2S_FER_1. 1 hit.
PS51085. 2FE2S_FER_2. 1 hit.
PS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-144 / Wilmington.

Entry informationi

Entry nameiSDHB_RICTY
AccessioniPrimary (citable) accession number: Q68XS0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: October 11, 2004
Last modified: November 26, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Rickettsia typhi
    Rickettsia typhi (strain Wilmington): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3