Q68XR3 (GCP_RICTY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	RT0093

Organism

Rickettsia typhi (strain ATCC VR-144 / Wilmington) [Complete proteome] [HAMAP]

Taxonomic identifier

257363 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length	387 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 387	387	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303525

Sequences

	Sequence		Length	Mass (Da)
	Q68XR3 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: E29017BB64063847	FASTA	387	42,546
	10 20 30 40 50 60 MKKILGIESS CDDTAISIIT ESRKILSNII IPQNTEHAVF GGVVPEIAAR SHLSNLDQAL 70 80 90 100 110 120 ENVLTKSNTE LTEISAIAAT SGPGLIGGVI VGSMFARSLS SALNKPFIAI NHLEGHALTV 130 140 150 160 170 180 RLTDNISYPY LLLLASGGHC QFVAVLGLGK YKILGSTIDD AIGETFDKVA KMLNLSFPGG 190 200 210 220 230 240 PEIEKRAKLG NPHKYKFPKP IINSGNCNMS FSGLKTAVRN LIMSLKEVND SVINDIAASF 250 260 270 280 290 300 QFTIGAILSS KMLNAIRLYQ QILNYYYENV DYTTNLNLKS FRQDEFNLNH LQDITRPKSR 310 320 330 340 350 360 IYLQNSFRSN LLNDTIVIAG GVAANKYLQE ILSNCTQTYG YRLIAPPMHL CTDNAAMIAY 370 380 AGLERYNNKL FSPLNFCPKA KWSLEDI

References

[1]

"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae." McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. , Hong C., Yu X.-J., Walker D.H., Weinstock G.M. J. Bacteriol. 186:5842-5855(2004) [PubMed: 15317790] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017197 Genomic DNA. Translation: AAU03579.1.
RefSeq	YP_067061.1. NC_006142.1.
3D structure databases
ProteinModelPortal	Q68XR3.
ModBase	Search...
Protein family/group databases
MEROPS	M22.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2959131.
GenomeReviews	Gene locus RT0093 in contig AE017197_GR.
KEGG	rty:RT0093.
PATRIC	17909354. VBIRicTyp34752_0098.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304663.
OMA	KDCNFSY.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	RTYP257363:RT0093-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. IPR022437. RPE3. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit. TIGR03775. RPE3. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_RICTY

Accession

Primary (citable) accession number: Q68XR3

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	October 11, 2004
Last modified:	January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program