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Protein

DNA replication and repair protein RecF

Gene

recF

Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi33 – 408ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. single-stranded DNA binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA repair Source: UniProtKB-HAMAP
  2. DNA replication Source: UniProtKB-HAMAP
  3. SOS response Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA repair, DNA replication, SOS response

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciRTYP257363:GJEQ-108-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA replication and repair protein RecFUniRule annotation
Gene namesi
Name:recFUniRule annotation
Ordered Locus Names:RT0100
OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
Taxonomic identifieri257363 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000000604: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 360360DNA replication and repair protein RecFPRO_0000236139Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi257363.RT0100.

Structurei

3D structure databases

ProteinModelPortaliQ68XQ6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecF family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1195.
HOGENOMiHOG000269558.
KOiK03629.
OMAiQCSTGEQ.
OrthoDBiEOG6HTP3X.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00365. RecF.
InterProiIPR001238. DNA-binding_RecF.
IPR018078. DNA-binding_RecF_CS.
IPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
[Graphical view]
PfamiPF02463. SMC_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00611. recf. 1 hit.
PROSITEiPS00617. RECF_1. 1 hit.
PS00618. RECF_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q68XQ6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKNIFLHSLN LENYRNFKNL ELKIDNIPII LTGENGSGKT NILEAISLFY
60 70 80 90 100
PGRGLRSSKL TDICKTSEDY CRVKALLQSK LGIADFSTHI KRNSNRRITE
110 120 130 140 150
YNASKIANNE LSKFTSMVWL TPQMEGIFTS SSTDRRKFLD RIVYNFDTKH
160 170 180 190 200
AELLNKYEYY MHERNKILAE DIRDNNWLKI IEENMANISN IIANNRLKTI
210 220 230 240 250
RFMQQAIDEI ENEFPKADLS IDGIIEQKIL NVEEDIVSFI ITELYQTRSK
260 270 280 290 300
DKLLGRTSFG IHKSDFLVKH QKKNILAKFC STGEQKAILI AIILAEMNST
310 320 330 340 350
IKLTKITPIL LLDEIFVHLD DKRRQYLMDF FTALNIQLWV TATNLDGIEN
360
FANKAQLIKL
Length:360
Mass (Da):41,725
Last modified:October 11, 2004 - v1
Checksum:i6D8BA92151E64935
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017197 Genomic DNA. Translation: AAU03586.1.
RefSeqiYP_067068.1. NC_006142.1.

Genome annotation databases

EnsemblBacteriaiAAU03586; AAU03586; RT0100.
GeneIDi2958524.
KEGGirty:RT0100.
PATRICi17909372. VBIRicTyp34752_0107.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017197 Genomic DNA. Translation: AAU03586.1.
RefSeqiYP_067068.1. NC_006142.1.

3D structure databases

ProteinModelPortaliQ68XQ6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi257363.RT0100.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAU03586; AAU03586; RT0100.
GeneIDi2958524.
KEGGirty:RT0100.
PATRICi17909372. VBIRicTyp34752_0107.

Phylogenomic databases

eggNOGiCOG1195.
HOGENOMiHOG000269558.
KOiK03629.
OMAiQCSTGEQ.
OrthoDBiEOG6HTP3X.

Enzyme and pathway databases

BioCyciRTYP257363:GJEQ-108-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00365. RecF.
InterProiIPR001238. DNA-binding_RecF.
IPR018078. DNA-binding_RecF_CS.
IPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
[Graphical view]
PfamiPF02463. SMC_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00611. recf. 1 hit.
PROSITEiPS00617. RECF_1. 1 hit.
PS00618. RECF_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-144 / Wilmington.

Entry informationi

Entry nameiRECF_RICTY
AccessioniPrimary (citable) accession number: Q68XQ6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: October 11, 2004
Last modified: January 7, 2015
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia typhi
    Rickettsia typhi (strain Wilmington): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.