Reviewed, UniProtKB/Swiss-Prot Q68XQ6 (RECF_RICTY)

Names and origin

Protein names

Recommended name:
    DNA replication and repair protein recF

Gene names

Name:	recF
Ordered Locus Names:	RT0100

Organism

Rickettsia typhi [Complete proteome] [HAMAP]

Taxonomic identifier

785 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length	360 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	The recF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the recF family.

Ontologies

Keywords
Biological process	DNA damage DNA repair DNA replication SOS response
Cellular component	Cytoplasm
Ligand	ATP-binding DNA-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: HAMAP SOS response Inferred from electronic annotation. Source: HAMAP
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP single-stranded DNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 360	360	DNA replication and repair protein recF HAMAP MF_00365		PRO_0000236139
Regions
	Nucleotide binding	33 – 40	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q68XQ6-1 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: 6D8BA92151E64935	FASTA	360	41,725
	10 20 30 40 50 60 MKNIFLHSLN LENYRNFKNL ELKIDNIPII LTGENGSGKT NILEAISLFY PGRGLRSSKL 70 80 90 100 110 120 TDICKTSEDY CRVKALLQSK LGIADFSTHI KRNSNRRITE YNASKIANNE LSKFTSMVWL 130 140 150 160 170 180 TPQMEGIFTS SSTDRRKFLD RIVYNFDTKH AELLNKYEYY MHERNKILAE DIRDNNWLKI 190 200 210 220 230 240 IEENMANISN IIANNRLKTI RFMQQAIDEI ENEFPKADLS IDGIIEQKIL NVEEDIVSFI 250 260 270 280 290 300 ITELYQTRSK DKLLGRTSFG IHKSDFLVKH QKKNILAKFC STGEQKAILI AIILAEMNST 310 320 330 340 350 360 IKLTKITPIL LLDEIFVHLD DKRRQYLMDF FTALNIQLWV TATNLDGIEN FANKAQLIKL

References

[1]

"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae." McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. , Hong C., Yu X.-J., Walker D.H., Weinstock G.M. J. Bacteriol. 186:5842-5855(2004) [PubMed: 15317790] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017197 Genomic DNA. Translation: AAU03586.1.
RefSeq	YP_067068.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2958524.
GenomeReviews	Gene locus RT0100 in contig AE017197_GR.
KEGG	rty:RT0100.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG645124.
OMA	DDIMSHL.
Enzyme and pathway databases
BioCyc	RTYP257363:RT0100-MON.
Family and domain databases
HAMAP	MF_00365. [Tree]
InterPro	IPR001238. DNA-binding_RecF. IPR018078. DNA-binding_RecF_CS. IPR003395. RecF/RecN/SMC_N. [Graphical view]
Pfam	PF02463. SMC_N. 1 hit. [Graphical view]
PROSITE	PS00617. RECF_1. 1 hit. PS00618. RECF_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RECF_RICTY

Accession

Primary (citable) accession number: Q68XQ6

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 16, 2006
Last sequence update:	October 11, 2004
Last modified:	December 15, 2009
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)