Reviewed, UniProtKB/Swiss-Prot Q68XP1 (DHSC_RICTY)

Names and origin

Protein names

Recommended name:
    Succinate dehydrogenase cytochrome b556 subunit
      Short name=Cytochrome b-556

Gene names

Name:	sdhC
Ordered Locus Names:	RT0115

Organism

Rickettsia typhi [Complete proteome] [HAMAP]

Taxonomic identifier

785 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length	124 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Mono-heme cytochrome of the succinate dehydrogenase complex.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle.
Subunit structure	Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and an hydrophobic anchor protein.
Subcellular location	Cell inner membrane; Multi-pass membrane protein.
Sequence similarities	Belongs to the cytochrome b560 family.

Ontologies

Keywords
Biological process	Electron transport Transport Tricarboxylic acid cycle
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane
Ligand	Heme Iron Metal-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW succinate dehydrogenase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 124	124	Succinate dehydrogenase cytochrome b556 subunit		PRO_0000281052
Regions
	Transmembrane	35 – 55	21	Potential
	Transmembrane	68 – 88	21	Potential
	Transmembrane	104 – 124	21	Potential
Sites
	Metal binding	83	1	Iron (heme axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q68XP1-1 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: D1E11171444609DB	FASTA	124	14,464
	10 20 30 40 50 60 MTKIKQEIYN KRPTSPHLTI YKPQISSTLS ILHRMTGVAL FFVVSILVWW LILSKYDNNY 70 80 90 100 110 120 LQLARCCIIK ICLVAFSYAW CYHLCNGIRH LFWDIGYGFS IRAVNITGWC VVVCSILLTM LLWV

References

[1]

"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae." McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. , Hong C., Yu X.-J., Walker D.H., Weinstock G.M. J. Bacteriol. 186:5842-5855(2004) [PubMed: 15317790] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017197 Genomic DNA. Translation: AAU03601.1.
RefSeq	YP_067083.1.
3D structure databases
HSSP	HSSP built from PDB template 1NEK based on UniProtKB P69054.
ModBase	Search...
Genome annotation databases
GeneID	2958798.
GenomeReviews	Gene locus RT0115 in contig AE017197_GR.
KEGG	rty:RT0115.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q68XP1.
OMA	HRATGVF
Enzyme and pathway databases
BioCyc	RTYP257363:RT0115-MON.
Family and domain databases
InterPro	IPR000701. Succ_DH_cyt_bsu. IPR018495. Succ_DH_cyt_bsu_CS. IPR014314. Succ_DH_cytb556. IPR014361. Succ_DH_cytb560. [Graphical view]
Pfam	PF01127. Sdh_cyt. 1 hit. [Graphical view]
PIRSF	PIRSF000178. SDH_cyt_b560. 1 hit.
TIGRFAMs	TIGR02970. succ_dehyd_cytB. 1 hit.
PROSITE	PS01000. SDH_CYT_1. 1 hit. PS01001. SDH_CYT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DHSC_RICTY

Accession

Primary (citable) accession number: Q68XP1

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 20, 2007
Last sequence update:	October 11, 2004
Last modified:	November 24, 2009
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)