Reviewed, UniProtKB/Swiss-Prot Q68XP0 (DHSD_RICTY)

Names and origin

Protein names

Recommended name:
    Succinate dehydrogenase hydrophobic membrane anchor subunit

Gene names

Name:	sdhD
Ordered Locus Names:	RT0116

Organism

Rickettsia typhi [Complete proteome] [HAMAP]

Taxonomic identifier

785 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length	125 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Predicted.

General annotation (Comments)

Function	Putative hydrophobic component of the succinate dehydrogenase complex. Could be required to anchor the catalytic components to the cytoplasmic membrane.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle.
Subunit structure	Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and an hydrophobic anchor protein.
Subcellular location	Cell inner membrane; Multi-pass membrane protein.

Ontologies

Keywords
Biological process	Electron transport Transport Tricarboxylic acid cycle
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane
Ligand	Heme Iron Metal-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW succinate dehydrogenase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 125	125	Succinate dehydrogenase hydrophobic membrane anchor subunit		PRO_0000280981
Regions
	Transmembrane	25 – 45	21	Potential
	Transmembrane	65 – 85	21	Potential
	Transmembrane	102 – 122	21	Potential
Sites
	Metal binding	80	1	Iron (heme axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q68XP0-1 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: E706A13E55B89704	FASTA	125	14,523
	10 20 30 40 50 60 MIYDFKAEII KSKSSSSSKS GAHHWLLQRV TGVVLALCSF WLIYFMFTNK NNDINIIMWE 70 80 90 100 110 120 FKKPFNIVIL LITVTISLYH SVLGMRVVIE DYINCHKLRN TLIIIVKLFC ILTIVAFIVA IFYSE

References

[1]

"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae." McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. , Hong C., Yu X.-J., Walker D.H., Weinstock G.M. J. Bacteriol. 186:5842-5855(2004) [PubMed: 15317790] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017197 Genomic DNA. Translation: AAU03602.1.
RefSeq	YP_067084.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2958800.
GenomeReviews	Gene locus RT0116 in contig AE017197_GR.
KEGG	rty:RT0116.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q68XP0.
OMA	INIIMWE
Enzyme and pathway databases
BioCyc	RTYP257363:RT0116-MON.
Family and domain databases
InterPro	IPR014312. Succ_DH_anchor. IPR000701. Succ_DH_cyt_bsu. [Graphical view]
Pfam	PF01127. Sdh_cyt. 1 hit. [Graphical view]
TIGRFAMs	TIGR02968. succ_dehyd_anc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DHSD_RICTY

Accession

Primary (citable) accession number: Q68XP0

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 20, 2007
Last sequence update:	October 11, 2004
Last modified:	November 3, 2009
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)