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Q68XA0 (UCRI_RICTY) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ubiquinol-cytochrome c reductase iron-sulfur subunit

EC=1.10.2.2
Alternative name(s):
Rieske iron-sulfur protein
Short name=RISP
Gene names
Name:petA
Ordered Locus Names:RT0261
OrganismRickettsia typhi (strain ATCC VR-144 / Wilmington) [Complete proteome] [HAMAP]
Taxonomic identifier257363 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group

Protein attributes

Sequence length177 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.

Catalytic activity

Quinol + 2 ferricytochrome c = quinone + 2 ferrocytochrome c + 2 H+.

Cofactor

Binds 1 2Fe-2S cluster per subunit By similarity.

Subunit structure

The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

Subcellular location

Cell membrane; Single-pass membrane protein Potential.

Miscellaneous

The Rieske protein is a high potential 2Fe-2S protein.

Sequence similarities

Contains 1 Rieske domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 177177Ubiquinol-cytochrome c reductase iron-sulfur subunit
PRO_0000286644

Regions

Transmembrane18 – 3821Helical; Potential
Domain88 – 17588Rieske

Sites

Metal binding1201Iron-sulfur (2Fe-2S) By similarity
Metal binding1221Iron-sulfur (2Fe-2S); via pros nitrogen By similarity
Metal binding1391Iron-sulfur (2Fe-2S) By similarity
Metal binding1421Iron-sulfur (2Fe-2S); via pros nitrogen By similarity

Amino acid modifications

Disulfide bond125 ↔ 141 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q68XA0 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 3ADC9B2B6E69DB59

FASTA17719,191
        10         20         30         40         50         60 
MSDTEDNRNK QTTRRDFIVL TASSVAAVGA ACAFWPIIDS LNPSTDVLAL SSIEVDLSSI 

        70         80         90        100        110        120 
AIGQTVTVKW QGKPIFITNR TPDGIASARA VKMSELIDPE KDEVRVKAGH DNWLVTIGIC 

       130        140        150        160        170 
THLGCVPLSN QGEYNGWFCP CHGSQYDSSG RVRKGPASLN LVVPPYIFIS DTKIRIG 

« Hide

References

[1]"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae."
McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. expand/collapse author list , Hong C., Yu X.-J., Walker D.H., Weinstock G.M.
J. Bacteriol. 186:5842-5855(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017197 Genomic DNA. Translation: AAU03742.1.
RefSeqYP_067224.1. NC_006142.1.

3D structure databases

ProteinModelPortalQ68XA0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING257363.RT0261.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAU03742; AAU03742; RT0261.
GeneID2959250.
KEGGrty:RT0261.
PATRIC17909708. VBIRicTyp34752_0270.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0723.
HOGENOMHOG000255193.
KOK00411.
OMAFQGESKG.
OrthoDBEOG6RNQD9.
ProtClustDBCLSK870834.

Enzyme and pathway databases

BioCycRTYP257363:GJEQ-274-MONOMER.

Family and domain databases

Gene3D2.102.10.10. 1 hit.
InterProIPR017941. Rieske_2Fe-2S.
IPR014349. Rieske_Fe-S_prot.
IPR005805. Rieske_Fe-S_prot_C.
IPR006311. TAT_signal.
IPR019546. TAT_signal_bac_arc.
IPR019470. Ubiq_cytC_Rdtase_Fe-S_su_TAT.
IPR006317. Ubiquinol_cyt_c_Rdtase_Fe-S-su.
[Graphical view]
PANTHERPTHR10134. PTHR10134. 1 hit.
PfamPF00355. Rieske. 1 hit.
PF10399. UCR_Fe-S_N. 1 hit.
[Graphical view]
PRINTSPR00162. RIESKE.
SUPFAMSSF50022. SSF50022. 1 hit.
TIGRFAMsTIGR01416. Rieske_proteo. 1 hit.
TIGR01409. TAT_signal_seq. 1 hit.
PROSITEPS51296. RIESKE. 1 hit.
PS51318. TAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUCRI_RICTY
AccessionPrimary (citable) accession number: Q68XA0
Entry history
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: October 11, 2004
Last modified: April 16, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia typhi

Rickettsia typhi (strain Wilmington): entries and gene names